Not yet recruitingNCT06864559Updated Mar 7, 2025

Comparison of Three Types of Sutures in Oral Surgery. Study of Bacterial Colonization, Tissue Reaction and Clinical Characteristics: Randomized Clinical Study

An interventional study of To Compare 3 different suture materials used in oral surgery in Wound Healing Complication, Oral Surgery and Third Molar Extraction, sponsored by Universidad de Granada. Not yet recruiting. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-03-07.

Sponsored by Universidad de Granada · Not applicable, Interventional, and Treatment

From the registry’s dates

Primary completion was expected by Sep 2025, 1 year 1 month ago, but the record still lists the study as not yet recruiting.

Phase: Not applicable
Study type: Interventional
Enrollment: 24
Allocation: Randomized
Ages: 18 Years and older
Sex: All

Study summary

Considering the wide variety of surgical sutures currently marketed in the field of Dentistry, it was decided to conduct a study comparing the microbial adhesion and antibacterial activity of three different types of sutures used in Oral Surgery (Silk, non-absorbable polyamide monofilament and non-absorbable expanded polytetrafluoroethylene).

Read the detailed description

The general or primary objective is:

To compare 3 non-absorbable suture materials used in oral surgery: silk, polyamide monofilament and expanded polytetrafluoroethylene.

The specific or secondary objectives are:

To evaluate how each type of suture influences wound healing and the patient's postoperative period.
To study bacterial colonization in each type of suture.
To determine the tissue reaction and clinical characteristics of each suture.

Conditions studied

Wound Healing Complication
Oral Surgery
Third Molar Extraction
Oral Infection

In context

Lead sponsor

Universidad de Granada is the lead sponsor of 241 studies on the registry; 41 are open to participants now.

Counted across the registry records on this site, refreshed daily.

Who can participate

Ages eligible: 18 Years and older
Sexes eligible: All
Accepts healthy volunteers: No

Inclusion criteria

Patients with indication for extraction of a third lower molar retained in an unfavorable position that requires a bayonet incision in the surgical procedure.
Age: patients aged 18 years or older.
ASA I patients (Classification of the American Society of Anesthesiology, 1979): healthy patients who tolerate stress well, without systemic pathology, no anxiety and in whom a therapeutic modification is not necessary.

Exclusion criteria

Exclusion Criteria:

Pregnant or breastfeeding women.
Smoking patients.

Study design

Phase: Not applicable
Primary purpose: Treatment
Allocation: Randomized
Intervention model: Single group
Masking: None (open label)
Enrollment: 24 participants (estimated)

Study arms

Other
Suture 1: Silk.
Silk suture.
Other: To Compare 3 different suture materials used in oral surgery
Other
Suture 2: Non-absorbable polyamide monofilament.
Non-absorbable polyamide monofilament.
Other: To Compare 3 different suture materials used in oral surgery
Other
Suture 3: Non-resorbable expanded polytetrafluoroethylene.
Non-resorbable expanded polytetrafluoroethylene.
Other: To Compare 3 different suture materials used in oral surgery

Interventions

OtherTo Compare 3 different suture materials used in oral surgery
To compare bacterial colonization, tissue reaction and clinical characteristics such as wound healing and patient postoperative outcomes in 3 different suture materials used in oral surgery.
Also known as: 2028/CEIH/2021

What researchers measure

Primary outcomes

Bacterial colonization
Microbiological analysis: CFU and qPCR bacterial count.
Time frame: 7 days.
Level of inflammation
The degree of soft tissue inflammation was assessed using Visual Analogue Scale (VAS).
Time frame: 7 days.

Study locations

No study locations are listed for this record.

Updates

Tracking since Sep 25, 2026

No changes since tracking began. The registry record was last updated on Mar 7, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗

Registry details

Key details

Study ID: NCT06864559
Lead sponsor: Universidad de Granada
Responsible party: Jose Manuel Alarcón Cordovilla (DDS (University of Granada), MSc (Oral Surgery), Universidad de Granada) — Principal investigator
First posted: Mar 7, 2025
Start date: Mar 1, 2025 (estimated)
Primary completion: Sep 1, 2025 (estimated)
Completion: Dec 1, 2025 (estimated)
Last update: Mar 7, 2025

Oversight

FDA-regulated drug: No
FDA-regulated device: No

View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Mar 2025. You cannot join it, but the record below documents what was studied.

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