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RecruitingNCT06841419Updated May 13, 2025

Reliability and Versatility of Pedicled Anterolateral Thigh Flap in Reconstruction of Soft Tissue Defects

An interventional study of surgical reconstruction of a soft tissue defects by a pedicled flap in Post Traumatic Soft Tissue Defects That Could be Reached by Pedicled Anterolateral Thigh Flap, Post Tumor Excision Soft Tissue Defects and Post Debridement Soft Tissue Defects, sponsored by Sohag University. Recruiting at 1 site in Egypt. Per ClinicalTrials.gov, last updated 2025-05-13.

Sponsored by Sohag University · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Primary completion was expected by Oct 2025, 1 year ago, but the record still lists the study as recruiting.
  • Started Feb 2025; still recruiting 1 year 8 months later.
Phase
Not applicable
Study type
Interventional
Enrollment
20
Allocation
Not applicable
Sex
All
01

Study summary

a prospective case series study for evaluation of the reliability and versatility of pedicled anterolateral thigh flap in the reconstruction of soft tissue defects as regards flap survival and complications, donor site morbidity and aesthetic outcome.

02

Conditions studied

  • Post Traumatic Soft Tissue Defects That Could be Reached by Pedicled Anterolateral Thigh Flap
  • Post Tumor Excision Soft Tissue Defects
  • Post Debridement Soft Tissue Defects
03

In context

Lead sponsor

Sohag University is the lead sponsor of 1,220 studies on the registry; 629 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • All patients with clean hip, thighs or lower abdomen defects either traumatic or non_traumatic that cannot be closed primarily.

Exclusion criteria

Exclusion Criteria:

  • Patients with possible compromise of vascular pedicle due to previous trauma or surgery.
  • Patient refusal
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
20 participants (estimated)

Study arms

  • Experimental
    a group of patients with hip, thighs, knees and lower abdomen regions soft tissue defects

    treating patients of the group mentioned by reconstructing their tissue defects by pedicled anterolateral thigh flap.

    Procedure: surgical reconstruction of a soft tissue defects by a pedicled flap

Interventions

  • Proceduresurgical reconstruction of a soft tissue defects by a pedicled flap

    harvesting of a fasciocutaneous flap from the anterolateral aspect of thigh based on a perforators from the descending branch of lateral femoral circumflex artery to reconstruct a neighboring soft tissue defect.

06

What researchers measure

Primary outcomes

  1. Flap Survival Rate

    The percentage of flaps that survive completely without necrosis or partial loss. Complications will be graded (e.g., total flap loss, partial necrosis, or marginal necrosis). Unit: Percentage. Measurement Tool: ruler/(Mesure).

    Time frame: "From enrollment to the end of treatment at 8 weeks"

Secondary outcomes

  1. Range of Motion in Reconstructed Area

    Assessment of the range of motion in the reconstructed area. Unit: Degrees. Measurement Tool: Goniometer.

    Time frame: "From enrollment to the end of treatment at 8 weeks"

  2. Strength in Reconstructed Area

    Evaluation of muscle strength in the reconstructed area. Unit: Newton (N). Measurement Tool: Dynamometer.

    Time frame: "From enrollment to the end of treatment at 8 weeks"

07

Study locations

1 of 1 sites recruiting
  • Sohag university Hospitals
    Sohag, 82511, Egypt
    Recruiting
08

References and documents

Individual participant data

Plan to share: Undecided

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 13, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT06841419
Lead sponsor
Sohag University
Responsible party
Abdelnasser Mohamed Ahmed (Resident in Plastic Surgery Department Suhag university, Sohag University) — Principal investigator
First posted
Feb 24, 2025
Start date
Feb 15, 2025
Primary completion
Oct 2025 (estimated)
Completion
Dec 2025 (estimated)
Last update
May 13, 2025

Study contacts

Abdelnaser Mohamed Ahmed, resident in Plastic surgery
Contact
dr.nasser5656@gmail.com
+20 01550435303

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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