An interventional study of Baduanjin exercise training (BET) in Chronic COVID-19 Syndrome, sponsored by Cairo University. Recruiting at 1 site in Egypt. Open to participants aged 18 Years to 50 Years. Per ClinicalTrials.gov, last updated 2025-02-17.
Sponsored by Cairo University · Not applicable, Interventional, and Treatment
Post-COVID recovery is associated with reduced functional fitness/capacity, low quality of life, and physical disabilities in those who survived after contracting the disease. The unpleasant symptoms of chronic post-viral/post-COVID syndrome (chronic fatigue perception, variant nonspecific myalgia, bad mood or depression, and insomnia or sleep disturbances) usually magnify the symptoms of already existing previously diagnosed concurrent untreatable chronic disorders , including the idiopathic chronic fatigue (ICF).(Leszczak et al., 2024)
Baduanjin exercise training (BET) is one of the Chinese traditional Health-Qigong exercises that not only integrate slow coordinating postures/positions, breathing techniques, musculoskeletal stretching movements/positions, and meditative mind but also plays a strong role concerning health benefits (e.g. musculoskeletal pain-reducing, sleep disturbance-enhancing effects, and fatigue-reducing effects) (Zou et al., 2018).
forty idiopathic chronic fatigue (ICF) patients will be randomly assigned into two equal groups (n=20)
7,640 studies on the registry are indexed under COVID-19; 488 are open to participants now.
This study's planned enrollment of 40 is below the median of 100 across 4,099 interventional studies indexed under COVID-19.
Browse COVID-19 studies →Cairo University is the lead sponsor of 4,780 studies on the registry; 1,427 are open to participants now.
Of its 36 completed or terminated interventional studies of FDA-regulated products, 5 (14%) have results posted.
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40 patients will be recruited in the study.
At least three of the following symptoms:
Generalized muscle weakness Difficulty sleeping Frequent headaches A painful throat Muscle tenderness throughout the body Migratory joint pain Swollen lymph nodes in the neck or armpits Fatigue lasting more than a day after typical activities
Exclusion Criteria:
Each BET session consisted of a 10-minute warm-up and a 10-minute cool-down period \[Xia et al., 2023\]. These were followed by a 40-minute BET segment, which typically involved eight distinct body postures. These postures are based on the "Health Qigong Baduanjin Standard," as outlined in Zhao et al. \[2019\] and Koh \[1982\]. The eight postures are: (1) Support the Heaven, (2) Draw a Bow to Each Side, (3) Hold Up a Single Hand, (4) Practice Looking Back, (5) Shake the Hand and Wag the Tail, (6) Touch the Feet with Both Hands, (7) Climbing with Both Hands, and (8) Relax the Back, as explained in Zeng et al. \[2020\]
Other: Baduanjin exercise training (BET)
this group will receive no intervention
Baduanjin Exercise Training (BET) is a traditional Chinese exercise focused on improving physical health, flexibility, balance, and mental well-being. It involves a 10-minute warm-up, a 40-minute core session practicing eight distinct postures, and a 10-minute cool-down. The postures, based on the Baduanjin form, target different body parts and promote strength, flexibility, and circulation. The exercises are synchronized with deep breathing to enhance relaxation and stress reduction. BET is especially beneficial for joint health, mobility, and mental clarity, making it suitable for individuals of all ages and fitness levels
Pulmonary function: By Spirometry Device:
• Pulmonary function: By Spirometry Device: it measure ventilatory functions. forced vital capacity (FVC)
Time frame: By Spirometry Device: forced vital capacity will be measured at baseline, and it will be measured after twelve weeks again
Pulmonary function: By Spirometry Device:
Pulmonary function: By Spirometry Device: it measure ventilatory functions forced expiratory volume in one second (FEV1)
Time frame: By Spirometry Device forced expiratory volume in one second (FEV1) will be measured at baseline, and it will be measured after twelve weeks again
Measuring functional capacity: By Six-minute walk test (6MWT)
Measuring functional capacity: By Six-minute walk test (6MWT): is a self paced submaximal field exercise test , It will be performed according to the standard procedure is administered in a 30 meter hallway. (Launois et al., 2012 and ATS statement2002)
Time frame: Measuring functional capacity: By Six-minute walk test (6MWT)::will be measured at baseline, and it will be measured again after twelve weeks
Modified Borg dyspnea scale (MBDS)
Modified Borg dyspnea scale (MBDS) is patient self-reported measures of one's difficulty in breathing upon exertion
Time frame: Modified Borg dyspnea scale (MBDS) will be measured at baseline, and it will be measured again after twelve weeks
Strength of lower limb muscles By a thirty-second sit-to-stand test
thirty-second sit-to-stand test was designed for testing leg strength and endurance it is the number of repetitions of sit-to-stand action executed in thirty seconds
Time frame: thirty-second sit-to-stand test will be measured at baseline, and it will be measured again after twelve weeks
Endurance of upper limb muscles: by the maximal repetitions of push-ups (MRPU).
Endurance of upper limb muscles: by the maximal repetitions of push-ups (MRPU) is commonly used to assess upper body strength, muscular endurance, and overall fitness levels.
Time frame: the maximal repetitions of push-ups (MRPU). will be measured at baseline, and it will be measured again after twelve weeks
Cardiorespiratory fitness:by the index of Ruffier test (IRT).
Cardiorespiratory fitness: by the index of Ruffier test (IRT). is a simple, non-invasive method used to assess the recovery capacity of the heart after exercise and can be used to monitor fitness improvements over time.
Time frame: Cardiorespiratory fitness:by the index of Ruffier test (IRT). will be measured at baseline, and it will be measured again after twelve weeks
Quality of life: by the short form 36 questionnaire (SF)
Quality of life: by the short form 36 questionnaire (SF) is a set of generic, coherent, and easily administered quality-of-life measures. These measures rely upon patient self-reporting and have been widely used
Time frame: Quality of life: by the short form 36 questionnaire (SF) will be measured at baseline, and it will be measured again after twelve weeks
sleep quality by Pittsburgh sleep quality index (PSQI):
sleep quality by Pittsburgh sleep quality index (PSQI): This is a 19 item widely used self-report questionnaire designed to assess sleep quality and disturbances
Time frame: sleep quality by Pittsburgh sleep quality index (PSQI):will be measured at baseline, and it will be measured again after twelve weeks
Beck Depression Inventory (BDI):
Beck Depression Inventory (BDI):widely used self-report questionnaire designed to assess the presence and severity of depressive symptoms
Time frame: Beck Depression Inventory (BDI):will be measured at baseline, and it will be measured again after twelve weeks
fatigue assessment by Buzhongyiqi-Tang questionnaire (BZTQ):
Buzhongyiqi-Tang questionnaire (BZTQ): Fatigue syndrome's severity can be rated via this validated 16-item questionnaire (every item was rated 7-Likert scale responses starting from zero to seven).
Time frame: Buzhongyiqi-Tang questionnaire (BZTQ)::will be measured at baseline, and it will be measured again after twelve weeks
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