An interventional study of Intratechal Morphine and Transversalis Fascia Plane Block in Abdominal Hysterectomy, sponsored by Ataturk Training and Research Hospital. Recruiting at 1 site in Turkey. Open to female participants aged 18 Years to 65 Years. Per ClinicalTrials.gov, last updated 2025-02-19.
Sponsored by Ataturk Training and Research Hospital · Not applicable, Interventional, and Other
Hysterectomy is one of the most commonly performed surgical procedures after cesarean section in many countries worldwide, especially among women of reproductive age. Postoperative pain is typically managed with oral and parenteral narcotics. Patient-controlled analgesia (PCA) is an effective pain management method that provides advantages such as faster pain relief, better dosage control, and elimination of the need for timer adjustments. Facilitating the recovery process and optimizing postoperative pain management are crucial components of perioperative care. To minimize systemic opioid requirements and opioid-related side effects, multimodal analgesia combining local anesthesia, peripheral, and non-opioid analgesics has become increasingly popular.
Exclusion Criteria:
Other: Intratechal Morphine
Other: Transversalis Fascia Plane Block
Prior to induction, the patient will be positioned seated, and morphine will be slowly injected intrathecally at a dose of 5 μg/kg, adjusted to the L4-L5 or L3-L4 intervertebral space using a 27G pencil point spinal needle. The injection will be administered over approximately 10 seconds
Prior to induction, patients will be positioned supine, and bilateral transversus abdominis plane (TAP) block will be performed with the aid of ultrasound. As the blocking agent, 20 cc of 0.25% bupivacaine will be used bilaterally.
Postoperatve Opioid Consumption
The primary aim of this study is to compare the analgesic efficacy of intrathecal morphine and bilateral transversalis fascia plane block in patients undergoing elective abdominal hysterectomy, in terms of morphine consumption during the first 24 hours postoperatively
Time frame: postoperatively 24 hours
Postoperative Pain Scores at movement and rest
evaluation of pain scores during movement and rest within 24 hours postoperatively using Visual Analogue Scale
Time frame: postoperatively 24 hours
Quality of recovery 24 hours after the surgery assessed using QoR-40 questionnaire
Evaluation of quality of recovery 24 hours after the surgery assessed using QoR-40 questionnaire
Time frame: postoperative 24 hour
Advers Event
incidence of side effects (nause, vomiting, urinary retention) for 24 hours
Time frame: postoperative 24 hour
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Ataturk Training and Research Hospital