ClinicalTrials.gg
CompletedNCT06810115Updated Feb 5, 2025

Respiatory Viral Infections in Patients With Multiple Myeloma

An observational study in Multiple Mieloma and Respiratory Viral Infections, sponsored by University Medical Centre Ljubljana. Completed. Per ClinicalTrials.gov, last updated 2025-02-05.

Sponsored by University Medical Centre Ljubljana · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
219
Sex
All
01

Study summary

Respiratory viruses are known to be a major cause of morbodity in multiple myeloma patients but prospective long-term sudies are lacking. We analysed 219 multiple myeloma patients that had 554 nasopharingeal swabs with 58 documented viral episodes. Respiratory viruses studied were rhinovirus, enterovirus, parainflienza, respirator, syncytial virus, metapneumovirus, coronavirus, bocavirus, influenza A, influenza B. Clinical data were extracted from a prospectively entered database, medical records were reviewed. We have prospectively studiend patients until May 2019 when we gathered survival data. Lastly because of Covid-19 pandemic when almost no other viral infections were isolated, we analysed clinical course of respiratory infections in patients with multiple myeloma after the pandemic.

02

Conditions studied

  • Multiple Mieloma
  • Respiratory Viral Infections

Keywords

  • Respiratory viral infections
03

In context

Lead sponsor

University Medical Centre Ljubljana is the lead sponsor of 294 studies on the registry; 72 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Patient with multiple myeloma on observation/receiving treatment at outpatient clinuc

Eligibility criteria

Inclusion Criteria:

  • Patients with multiple myeloma

Exclusion Criteria:Other hematological malignancies

-

05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
219 participants (actual)
Patient registry
No
Biospecimen retention
Samples with dna

Groups and cohorts

  • Patient with multiple myeloma

    Other: Viral PCR test

Interventions

  • OtherViral PCR test

    Viral PCR test regardles of symptoms

06

What researchers measure

Primary outcomes

  1. Number of respiratory viral infections in patirnts with multiple myeloma

    Time frame: 1 year

07

Study locations

No study locations are listed for this record.

08

References and documents

Publications

  • Blimark C, Holmberg E, Mellqvist UH, Landgren O, Bjorkholm M, Hultcrantz M, Kjellander C, Turesson I, Kristinsson SY. Multiple myeloma and infections: a population-based study on 9253 multiple myeloma patients. Haematologica. 2015 Jan;100(1):107-13. doi: 10.3324/haematol.2014.107714. Epub 2014 Oct 24. PubMed 25344526 ↗

Individual participant data

Plan to share: Undecided

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Ran from Oct 2015 to primary completion in May 2019, 43 months.

How these figures are worked out, and which studies are left out of them.

Registered
Jan 30, 2025
First posted
Feb 5, 2025
StartActual
Oct 1, 2015
Primary completionActual
May 1, 2019
CompletionActual
Oct 1, 2024
Last update
Feb 5, 2025
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Feb 5, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT06810115
Responsible party
Polona Novak (Polona Novak, MD, University Medical Centre Ljubljana) — Principal investigator
First posted
Feb 5, 2025
Start date
Oct 1, 2015
Primary completion
May 1, 2019
Completion
Oct 1, 2024
Last update
Feb 5, 2025

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Mar 2015. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion