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CompletedNCT06801301Updated Jan 30, 2025

Comparing Effects of Whole Body Vibration and Resisted Training on Quadriceps Strength After Lower Limb Burns

An interventional study of whole body vibration and Resistance Exercise in Lower Limb Burn and Muscle Weakness Condition, sponsored by Cairo University. Completed at 1 site in Egypt. Open to participants aged 25 Years to 40 Years. Per ClinicalTrials.gov, last updated 2025-01-30.

Sponsored by Cairo University · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 1 year 8 months after the study started (first participant enrolled May 2023, registered Jan 2025).
Phase
Not applicable
Study type
Interventional
Enrollment
60
Allocation
Randomized
Ages
25 Years to 40 Years
Sex
All
01

Study summary

Evaluate the therapeutic effect of Whole body vibration and Resistance training on strength of quadriceps post lower limb burn

Read the detailed description

Study Design:

This randomized controlled trial will include 60 patients suffering from partial thickness burns. The patients will be randomly divided into two equal groups, with each group consisting of 30 patients.

Study Explanation:

A verbal explanation about the importance of the study, its procedures, main aims, and conceptual approach will be provided to every patient.

Study Procedures:

The procedures of this study will be divided into two main categories: evaluation procedures and treatment procedures.

Evaluation Procedures:

Evaluation will be conducted using isokinetic dynamometry for all patients both before and after the study.

Treatment Procedures:

First Group: Patients in the first group will receive whole body vibration therapy.

Second Group: Patients in the second group will undergo resisted exercises.

02

Conditions studied

  • Lower Limb Burn
  • Muscle Weakness Condition

Keywords

  • Burn
  • Whole Body Vibration
  • Resisted Exercise
  • Isokinetic
03

In context

Muscle Weakness

601 studies on the registry are indexed under Muscle Weakness; 99 are open to participants now.

This study's enrollment of 60 is above the median of 46 across 444 interventional studies indexed under Muscle Weakness.

Browse Muscle Weakness studies →

Lead sponsor

Cairo University is the lead sponsor of 4,780 studies on the registry; 1,427 are open to participants now.

Of its 36 completed or terminated interventional studies of FDA-regulated products, 5 (14%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
25 Years to 40 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

The subject selection will be according to the following criteria:

  • Age range between 25-40 years.
  • Male and female patients will participate in the study.
  • All patients have burn of 30% to 40%.
  • All patients have burn at lower limb
  • All patients have second degree burn
  • All patients have no chronic diseases.
  • All patients enrolled to the study will have their informed consent

Exclusion criteria

Exclusion Criteria:

The potential participants will be excluded if they meet one of the following criteria:

  • Prosthesis;
  • Any neurological, musculoskeletal,or other chronic disease
  • Participation in an outside resistance training programs
  • Recent fracture or bone injury
  • Any medication that could affect strength adaptations and adversely affect the results of the study
  • Previous brain injury
  • Any disease affecting balance, vestibular or visual disorders
  • History of epilepsy.
  • Cardiac diseases.
  • Burn of sole of foot.
  • Exposed foot tendons.
  • Severe osteopathy.
  • Marked anemia (Ht\<25%).
  • Serious peripheral vessel disease
  • Acute medical problem at study onset.
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
60 participants (actual)

Study arms

  • Experimental
    group A

    whole body vibration group

    Device: whole body vibration

  • Active comparator
    group B

    resistance exercises

    Other: Resistance Exercise

Interventions

  • Devicewhole body vibration

    Standing in different static positions or exercising on a vibrating platform.The mechanical stimuli of vibration transmitted to the body and stimulate muscle spindles which activate the alpha motor neurons and initiates muscle contractions comparable to the ''tonic vibration reflex. The effect of WBV on the neuromuscular properties of skeletal muscles and spinal mechanisms is demonstrated by a decreased electromechanical delay.

  • OtherResistance Exercise

    Resistance training as a mode of exercise to promote several health benefits, including improvements in the muscle mass and strength of healthy adults.Resistance training, where muscles are required to contract against an opposing load, has been shown to be a beneficial form of rehabilitation in clinical populations prone to muscle wasting, providing stimuli to increase protein synthesis and muscle mass.

06

What researchers measure

Primary outcomes

  1. Increase in quadriceps muscle strength, assessed by an isokinetic dynamometer, which measures the peak torque of the quadriceps.

    Time frame: 8 weeks

07

Study locations

1 site
  • Faculty of physical therapy cairo university
    Cairo, 12613, Egypt
08

References and documents

Individual participant data

Plan to share: Yes

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 30, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT06801301
Lead sponsor
Cairo University
Responsible party
Salah mohamed shafiek abuelfadl (Physiotherapy Specialist, Cairo University) — Principal investigator
First posted
Jan 30, 2025
Start date
May 1, 2023
Primary completion
Jul 1, 2024
Completion
Aug 1, 2024
Last update
Jan 30, 2025

Study contacts

Eman Mohamed Othman, doctoral degree
study director · Cairo University
Khadra Mohamed Ali, Doctoral degree
study chair · Cairo University
Ashraf El Sebaie Mohamed, doctoral
study director · Cairo University

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Jan 2025. You cannot join it, but the record below documents what was studied.

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