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Not yet recruitingNCT06761794Updated Jan 7, 2025

Normogram of Umbilical Artery and Fetal Middle Cerebral Artery Doppler Indices in Upper Egyptian Women

An observational study in Doppler in Normal Pregnancy, sponsored by Assiut University. Not yet recruiting. Open to female participants. Per ClinicalTrials.gov, last updated 2025-01-07.

Sponsored by Assiut University · Observational

From the registry’s dates

  • Primary completion was expected by Jan 2026, 9 months ago, but the record still lists the study as not yet recruiting.
Study type
Observational
Model
Cohort
Time perspective
Cross-sectional
Enrollment
520
Sex
Female
01

Study summary

settle umbilical and fetal middle cerebral arteries Doppler indices( pulsatility index and resistive index) in normal pregnancy to generate a local reference range and calculate cerebroplacental ratio.

02

Conditions studied

  • Doppler in Normal Pregnancy
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In context

Lead sponsor

Assiut University is the lead sponsor of 4,901 studies on the registry; 2,098 are open to participants now.

Of its 13 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
Female
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Pregnant women with gestational age 15-40 wk, singleton fetus with no anomalies, free of medical and obstetric complications.

Inclusion criteria

  1. Singleton pregnancy between 15 and 40 weeks gestational age.
  2. Sure of her date (well-known LMP or confirmed date by an early ultrasound).
  3. Normal fetal anatomy.
  4. No history of medical disorders.

Exclusion criteria

Exclusion Criteria:

  1. Multiple pregnancy
  2. Fetal anomalies.
  3. Associated medical disorders.
  4. Obstetric complications.
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Study design

Observational model
Cohort
Time perspective
Cross-sectional
Enrollment
520 participants (estimated)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. pulsatility index of umbilical artery.

    Time frame: Through study completion, an average of 1 year

  2. Resistive index of umbilical artery

    Time frame: Through study completion, an average of 1 year

  3. pulsatility index of fetal middle cerebral artery.

    Time frame: Through study completion, an average of 1 year

  4. Resistive index of fetal middle cerebral artery

    Time frame: Through study completion, an average of 1 year

Secondary outcomes

  1. settle cerebroplacental ratio local reference range.

    Time frame: Through study completion, an average of 1 year

07

Study locations

No study locations are listed for this record.

08

References and documents

Publications

  • Acharya G, Wilsgaard T, Berntsen GK, Maltau JM, Kiserud T. Reference ranges for serial measurements of umbilical artery Doppler indices in the second half of pregnancy. Am J Obstet Gynecol. 2005 Mar;192(3):937-44. doi: 10.1016/j.ajog.2004.09.019. PubMed 15746695 ↗
  • Mari G. Middle cerebral artery peak systolic velocity for the diagnosis of fetal anemia: the untold story. Ultrasound Obstet Gynecol. 2005 Apr;25(4):323-30. doi: 10.1002/uog.1882. No abstract available. PubMed 15789353 ↗
  • Ebbing C, Rasmussen S, Kiserud T. Middle cerebral artery blood flow velocities and pulsatility index and the cerebroplacental pulsatility ratio: longitudinal reference ranges and terms for serial measurements. Ultrasound Obstet Gynecol. 2007 Sep;30(3):287-96. doi: 10.1002/uog.4088. PubMed 17721916 ↗
  • Maulik D, Mundy D, Heitmann E, Maulik D. Umbilical artery Doppler in the assessment of fetal growth restriction. Clin Perinatol. 2011 Mar;38(1):65-82, vi. doi: 10.1016/j.clp.2010.12.004. PubMed 21353090 ↗
  • Tarzamni MK, Nezami N, Gatreh-Samani F, Vahedinia S, Tarzamni M. Doppler waveform indices of fetal middle cerebral artery in normal 20 to 40 weeks pregnancies. Arch Iran Med. 2009 Jan;12(1):29-34. PubMed 19111026 ↗
  • Dubiel M, Breborowicz GH, Marsal K, Gudmundsson S. Fetal adrenal and middle cerebral artery Doppler velocimetry in high-risk pregnancy. Ultrasound Obstet Gynecol. 2000 Oct;16(5):414-8. doi: 10.1046/j.1469-0705.2000.00278.x. PubMed 11169324 ↗
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 7, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT06761794
Lead sponsor
Assiut University
Responsible party
Salma Kamel Morsi Bakhit (Principal investigator, Assiut University) — Principal investigator
First posted
Jan 7, 2025
Start date
Jan 2025 (estimated)
Primary completion
Jan 2026 (estimated)
Completion
Apr 2026 (estimated)
Last update
Jan 7, 2025

Study contacts

Salma Kamel Bakhit, Graduate
Contact
salma0122858@gmail.com
0201094242196

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Dec 2024. You cannot join it, but the record below documents what was studied.

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