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Not yet recruitingNCT06754397Updated Dec 31, 2024

Diagnostic Accuracy of Magnetic Resonance Cholangiopancreatography in Patients With Obstructive Jaundice

An observational study in Obstructive Jaundice, sponsored by Sohag University. Not yet recruiting. Open to participants aged 15 Years to 89 Years. Per ClinicalTrials.gov, last updated 2024-12-31.

Sponsored by Sohag University · Observational

Study type
Observational
Model
Case-only
Time perspective
Prospective
Enrollment
50
Ages
15 Years to 89 Years
Sex
All
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Study summary

Evaluate the diagnostic accuracy of Magnetic Resonance Cholangiopancreatography (MRCP) compared with Ultrasound and Computed Tomography (CT) in patients with obstructive jaundice taking findings of ERCP/ PTC and histopathology as gold standard.

Read the detailed description

MRCP as a diagnostic role to determine the presence and severity of biliary and pancreatic ductal dilatation. It can also detect the length of the stricture as well as the exact cause and location of the obstructing lesion in comparison to other modalities.

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Conditions studied

  • Obstructive Jaundice
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Who can participate

Ages eligible
15 Years to 89 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Adult male and female patients clinically diagnosed obstructive jaundice are included in the study with positive laboratory tests.

Inclusion criteria

Adult male and female patients clinically diagnosed obstructive jaundice are included in the study with positive laboratory tests.

Exclusion criteria

Exclusion Criteria:

Patients with non-obstructive (prehepatic/hepatic) cause of jaundice. Patients having contraindications to perform MRI (Patients with any electrically, magnetically or mechanically activated implants, pacemaker, cochlear implants or any metallic orthopedic implants and claustrophobic patients).

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Study design

Observational model
Case-only
Time perspective
Prospective
Enrollment
50 participants (estimated)
Patient registry
No

Groups and cohorts

  • Patients diagnosed with obstructive jaundice

    MRCP as a role that is used as a non-invasive diagnostic tool for visualizing the pancreaticobiliary tree without the use of contrast media

    Diagnostic Test: Magnetic Resonance Cholangiopancreatography

Interventions

  • Diagnostic testMagnetic Resonance Cholangiopancreatography

    Three most important sequences included axial T2 weighted scan from liver to ampullary region followed by T2 weighted 3D FSE sequence acquired in coronal oblique plane using respiratory triggering by tying bellows over abdomen. After this breath hold HASTE sequence is acquired in coronal plane. Maximum intensity projection (MIP) and thick slab images are also used for interpretation. US, CECT and MRCP scans are interpreted by radiologists blinded to other imaging findings

    Also known as: Ultrasound, Computed tomography

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What researchers measure

Primary outcomes

  1. Diagnostic accuracy of Magnetic Resonance Cholangiopancreatography in patients with obstructive jaundice according to the findings

    Magnetic Resonance Cholangiopancreatography findings in patients with obstructive jaundice comparing to findings of ERCP/ PTC and histopathology .

    Time frame: Within twelve months

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Study locations

No study locations are listed for this record.

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References and documents

Individual participant data

Plan to share: Undecided

No publications or documents are linked to this record.

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Registry details

Key details

Study ID
NCT06754397
Lead sponsor
Sohag University
Responsible party
Demiana Mohsen Soliman (Radiological resident, Sohag University) — Principal investigator
First posted
Dec 31, 2024
Start date
Jan 2025 (estimated)
Primary completion
Dec 2025 (estimated)
Completion
Dec 2025 (estimated)
Last update
Dec 31, 2024

Study contacts

Demiana M Soliman, Resident
Contact
r.demiana.mohsen@gmail.com
01211992362
Hisham A Amin, A. professor
Contact
+20 115 115 2564
Magdy M Amin, Professor
study director · Medical research ethics committee - Sohag university

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Dec 2024. You cannot join it, but the record below documents what was studied.

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