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Not yet recruitingNCT06713356Updated Dec 3, 2024

US Vs MRI in Diagnosis of TMJ Internal Derangement

An observational study in TMJ Internal Derangement, sponsored by Assiut University. Not yet recruiting. Per ClinicalTrials.gov, last updated 2024-12-03.

Sponsored by Assiut University · Observational

From the registry’s dates

  • Primary completion was expected by Dec 2025, 10 months ago, but the record still lists the study as not yet recruiting.
Study type
Observational
Model
Other
Time perspective
Cross-sectional
Enrollment
39
Sex
All
01

Study summary

Compare the accuracy of ultrasonography and magnetic resonance imaging in the diagnosis of temporomandibular joint internal derangements.

Read the detailed description

Temporomandibular disorders (TMDs) are conditions that affect the temporomandibular joint (TMJ), often leading to pain and dysfunction. The most common cause of TMJ problems is internal derangements.

The term "internal derangements" refers to conditions with the articular disc displaced from its original position on the mandibular condyle.

Disc displacement may occur anteriorly, anterolaterally, laterally, anteromedially, medially, or posteriorly, but the latter is very rare.

Anterior disc displacement (ADD) is the most common ID condition and is usually divided into two categories: with reduction and without reduction. Each category has special features during closed and opened mouth positions. Therefore, the examination should include both positions.

Clinical examination alone isn't enough to diagnose TMJ problems, therefore additional imaging tests are often needed.

Magnetic resonance imaging (MRI) is the gold standard modality, however because of its limited availability, long scan time, and high cost, it is difficult to use MRI as a screening technique.

Ultrasound (US) has been recommended as an alternate diagnostic imaging modality for TMJ problems as it is less costly, non-invasive and capable of providing real-time imaging, presents an alternative diagnostic tool. Thus, the articular disc may be seen as the patient is opening and closing their mouth

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Conditions studied

  • TMJ Internal Derangement

Keywords

  • MRI
  • US
  • TMJ
  • internal derangement
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In context

Lead sponsor

Assiut University is the lead sponsor of 4,901 studies on the registry; 2,098 are open to participants now.

Of its 13 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Sampling method
Probability sample

Study population

Patients showing signs of TMJ internal derangements

Inclusion criteria

  • Patients showing signs of TMJ internal derangements

Exclusion criteria

Exclusion Criteria:

  • contraindications for MRI such as claustrophobia, heart pacemaker and metallic foreign body carriers.
  • patients in which the misaligned images or distortions due to motion artifacts made the interpretation of the MRI unreliable.
  • Previously operated TMJ.
05

Study design

Observational model
Other
Time perspective
Cross-sectional
Enrollment
39 participants (estimated)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. Comparison between US and MRI in diagnosis of TMJ disc displacement.

    Compare the accuracy of assessment of disc positioning by ultrasonography and magnetic resonance imaging in patients with TMJ disorders .

    Time frame: Baseline

07

Study locations

No study locations are listed for this record.

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References and documents

Publications

  • Emshoff R, Kriwanek S, Koller M, et al. Diagnostic accuracy of ultrasound in the assessment of the temporomandibular joint: a comparison with MRI. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics. 2022; 96(6):750-756.
  • Salamah T, Harefa GN. Diagnostic value and clinical significance of high-resolution ultrasonography compared to magnetic resonance imaging in diagnosing temporomandibular joint dislocation: a systematic review. Medical Journal of Indonesia. 2024 Mar; 33(1): 29-34.
  • Refaat MM, Yousef MI, Torky AA, Sarow ML. Ultrasonography compared to magnetic resonance imaging for the diagnosis of the temporomandibular joint disc displacement: Benha Journal of Applied Sciences. 2021 Nov; 6(6): 133-43.
  • Li C, Zhou J, Shi Y, Ye Z, Zhang C, Hou R, Li Z, You M. Diagnostic efficacy of quantitative ultrasonography for anterior disc displacement of the temporomandibular joint. Quant Imaging Med Surg. 2023 Oct 1;13(10):6446-6455. doi: 10.21037/qims-23-401. Epub 2023 Aug 3. PubMed 37869327 ↗
  • Minervini G, Nucci L, Lanza A, Femiano F, Contaldo M, Grassia V. Temporomandibular disc displacement with reduction treated with anterior repositioning splint: a 2-year clinical and magnetic resonance imaging (MRI) follow-up. J Biol Regul Homeost Agents. 2020 Jan-Feb;34(1 Suppl. 1):151-160. DENTAL SUPPLEMENT. PubMed 32064850 ↗
  • Talmaceanu D, Lenghel LM, Bolog N, Buduru S, Leucuta D, Rotar H. High-resolution ultrasound imaging compared to magnetic resonance imaging for temporomandibular joint disorders: An in vivo study. Eur J Radiol. 2020 Nov;132:109291. doi: 10.1016/j.ejrad.2020.109291. Epub 2020 Sep 17. PubMed 32980724 ↗
  • Moturi K. Internal derangements of temporomandibular joint. Temporomandibular Joint Disorders: Principles and Current Practice. 2021;: 189-207.
  • Palmer J, Durham J. Temporomandibular disorders. BJA Educ. 2021 Feb;21(2):44-50. doi: 10.1016/j.bjae.2020.11.001. Epub 2020 Dec 24. No abstract available. PubMed 33889429 ↗

Individual participant data

Plan to share: Undecided

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Dec 3, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT06713356
Lead sponsor
Assiut University
Responsible party
Norhan Anwar Kamal El Dein Hussien (Resident Doctor, Assiut University) — Principal investigator
First posted
Dec 3, 2024
Start date
Dec 2024 (estimated)
Primary completion
Dec 2025 (estimated)
Completion
Jan 2026 (estimated)
Last update
Dec 3, 2024

Study contacts

Norhan A. Kamal El-Din
Contact
norhan02468@gmail.com
01152982068
Sami A. Sayed
study director · Professor doctor
Omran K. Qenawy
study director · Assistant professor doctor

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Nov 2024. You cannot join it, but the record below documents what was studied.

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