Investigation of the Possibility of Determining Cerebrovascular Disease Based on Hemodynamic Information of Localized Brain Regions

1. For Hemorrhagic Stroke Patients :

   • Adults aged between 19 and 80 years.
   • Diagnosed with hemorrhagic stroke through clinical observation and neuroimaging.
   • First-time hemorrhagic stroke patients.
   • Hemorrhagic stroke onset between 2 weeks and 12 months prior to screening.
   • Hemorrhagic lesion located in the cortex or subcortex.
   • Not taking medications that could affect brain hemodynamics, such as - antihypertensives, anticoagulants, antiplatelets, or antidepressants.
   • Able to read and understand the informed consent form and participate in questionnaires with sufficient language proficiency.
   • Voluntarily agree to participate in the study and provide written consent, with the ability to complete the study duration.

2. For Ischemic Stroke Patients :

   • Adults aged between 19 and 80 years.
   • Diagnosed with ischemic stroke through clinical observation and neuroimaging.
   • First-time ischemic stroke patients.
   • Ischemic stroke onset between 2 weeks and 12 months prior to screening.
   • Ischemic lesion located in the cortex or subcortex.
   • Not taking medications that could affect brain hemodynamics, such as antihypertensives, anticoagulants, antiplatelets, or antidepressants.
   • Able to read and understand the informed consent form and participate in questionnaires with sufficient language proficiency.
   • Voluntarily agree to participate in the study and provide written consent, with the ability to complete the study duration.

3. For Healthy Adults :

   • Adults aged between 19 and 80 years.
   • No history of stroke or transient ischemic attack (TIA).
   • No stroke risk factors such as hypertension, diabetes, or hyperlipidemia.
   • No chronic diseases (e.g., cardiovascular disease, chronic kidney disease, chronic lung disease).
   • No psychiatric conditions (e.g., depression, schizophrenia).
   • Not taking medications that could affect brain hemodynamics, such as antihypertensives, anticoagulants, antiplatelets, or antidepressants.
   • Able to read and understand the informed consent form and participate in questionnaires with sufficient language proficiency.
   • Voluntarily agree to participate in the study and provide written consent, with the ability to complete the study duration.

Exclusion Criteria :

• History of head trauma in the past 6 months.
• Ongoing severe chronic diseases (e.g., heart failure, chronic kidney disease, chronic lung disease).
• Severe psychiatric disorders such as schizophrenia, major depression, or bipolar disorder.
• Use of medications that could influence brain hemodynamics (e.g., antihypertensives, anticoagulants, antiplatelets, or antidepressants).
• Participation in a study and use of experimental drugs within the past 30 days.
• Pregnant or breastfeeding women.
• Major surgery in the past 6 months.
• Acute infections or inflammatory diseases.
• Cognitive impairment or dementia.
• Neurological disorders.
• Inability to understand the study procedures or unwillingness to provide voluntary consent.
• Any other clinical concerns deemed inappropriate for participation by the principal investigator or study team.