An observational study in Nutritional Assessment, Physical Activity and Health, sponsored by Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement. Recruiting at 2 sites in France. Open to participants aged 55 Years to 75 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-03-27.
Sponsored by Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement · Observational
To better understand how diet influences health during aging, the French National Research Institute for Agriculture, Food and the Environment (INRAE) is working with the Gérontopôle Auvergne-Rhône-Alpes on a project called Part'AGE. Part'AGE is a participatory research project where researchers want to recruit 1,000 people aged between 55 and 75 years, men and women, living in Auvergne-Rhône-Alpes in urban or rural areas. The goal is to study eating habits and state of health. To do this, researchers will examine many factors that can influence them, such as physical activity, overall health, consumption patterns or territories. Researchers will collect detailed information to classify participants into different groups (food typologies) based on their eating habits and state of health. With this distribution, the goal is to be able to give each group personalized nutritional advice to age in better health.
To participate in the study, the participants will need to collect a few drops of blood from the end of the finger, a urine sample, and do some tests (mobility, oral health). It will also be necessary to fill out questionnaires on eating habits, physical activity, and other aspects that may influence health. The benefices for to participants will be to contribute to nutrition research and to receive personalized feedback and advices on eating habits.
The main objective of the study is to characterize the food consumption profile of a population of people aged 55 to 75, men and women, living in the Auvergne-Rhône-Alpes region, either in an urban or rural environment. The aim is to classify volunteers into dietary typologies associated with more or less successful aging. Thus, the investigators will classify volunteers into five dietary typologies:
For each of these dietary typologies, the investigators will explore the diversity of: cardio-metabolic capacities; diet; mobility; health status (oral health, intestinal health, stress, fatigue, anxiety, sleep, addictions); the psychological-socio-economic dimension; biological parameters obtained after the collection of biological samples.
This study will be entirely carried out by correspondence, without the volunteers needing to travel. Wide communication on the study will first be carried out in Auvergne-Rhône-Alpes. A phone number and an email address of the research team will be left for people wishing more information. Volunteers will directly contact the administrative agent in charge of selection in order to leave their contact details. The administrative agent will respond or contact the participants in return to present the study in its entirety, tell them about their rights, and check their eligibility. If they are eligible and interested, volunteers will be sent the information form and a connection guide by email or by post and an appointment will be scheduled for a dematerialized inclusion visit with a study investigator. The inclusion visit will be carried out remotely, from a secure platform. Upon receipt of consent, the investigators will assign an identification number to the volunteer and will trigger the sending by post of a phenotyping BOX to their home containing all the material necessary to carry out the study, accompanied by an explanatory note. The volunteers will connect to a secure platform to complete 29 questionnaires, will carry out functional tests and anthropometric measurements and will collect their biological samples (blood drops and urine). Volunteers will send their biological samples to the INRAE laboratory within 2 days of their collection.
In return, volunteers will have the opportunity to:
Participants will be recruited from the Auvergne-Rhône-Alpes region, taking care to recruit both urban and rural people.
Exclusion Criteria:
Participatory research: participants will carry out surveys, functional tests and urine and blood sampling completely independently
Classification of our study population into 5 dietary typologies associated with more or less successful aging
1. Typology "at risk of malnutrition": volunteers who do not cover their daily protein-energy needs, i.e. having daily protein-energy intakes estimated by food consumption data lower than the needs estimated by the Mifflin and St Jeor equation (based on anthropometric and physical activity measurements). 2. "Balanced diet without cardio-metabolic risk" typology: volunteers covering their daily protein-energy needs, with an aHEI (Alternative Healthy Eating Index) score greater than 80 and with a waist circumference less than or equal to 94 cm for men and 80 cm for women. 3. "Diet to improve without cardio-metabolic risk" typology: volunteers covering their daily protein-energy needs, with an aHEI score less than or equal to 80 and with a waist circumference less than or equal to 94 cm for men and 80 cm for women. 4. "Balanced diet with cardio-metabolic risk" typology: volunteers covering their daily protein-energy needs, with an aHEI score greater than 80 and with a waist circumference
Time frame: From enrollment to the end of the surveys at 30 days
Blood parameters and waist-to-hip ratio
Assessment of glucose, C-peptide, triglycerides, cholesterol, amino acids, prealbumin and CRP levels in fingertip blood collected at home, and waist-to-hip ratio.
Time frame: From enrollment to the end of the surveys at 30 day
Assessment of dietary habits and choices
Assessment of dietary habits and choices by: polyphenol-targeted food frequency questionnaire, appetite questionnaire (Council on Nutrition Appetite Questionnaire, CNAQ), questionnaire on food expectations and choices, on culinary practices, supply, and nutritional perceptions. Assessment of diet quality with various scores (DQI, PNNS-GS, DII) and post-hoc analyses.
Time frame: From enrollment to the end of the surveys at 30 day
Assessment of physical capacities and physical activity
Assessment of physical capacities and physical activity with the chair rise test, calf circumference measurement and two questionnaires (IPAQ, and RPAQ/ONAPS) aimed at assessing physical activity and sedentary lifestyle.
Time frame: From enrollment to the end of the surveys at 30 day
Assessment of several dimensions of health
Assessment of several dimensions of health: 1) oral health (masticatory performance, number of posterior functional units, GOHAI questionnaire on quality of life related to oral health, EAT-10 questionnaire on dysphagia/swallowing, XI questionnaire on dry mouth and the CIF questionnaire on oral dysfunctions); 2) intestinal health (intestinal transit questionnaire and intestinal comfort questionnaire (IGQ); 3) various aspects of quality of life (stress, fatigue, anxiety, sleep, addictions, etc.).
Time frame: From enrollment to the end of the surveys at 30 day
Assessment of psycho-socio-economic status
Assessment of psycho-socio-economic status: questionnaire on precariousness (EPICES score), loneliness (De Jong Gierveld scale), desired healthy aging, quality of life (CAPS-19 scale), well-being profile, satisfaction and frustration of basic psychological needs. Assessment of personality traits and budget dedicated to food purchases.
Time frame: From enrollment to the end of the surveys at 30 day
Collection of blood and urine samples.
Collection of blood and urine samples.
Time frame: From enrollment to the end of the surveys at 30 day
Plan to share: No — As soon as possible, results will be published. Upon requests, sharing of data could be considered on a case-by-case basis.
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Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement