An observational study in CABP2-related Auditory Synaptopathy and Hearing Impairment, sponsored by University Medical Center Goettingen. Recruiting at 1 site in Germany. Per ClinicalTrials.gov, last updated 2026-01-27.
Sponsored by University Medical Center Goettingen · Observational
This registry is designed to collect comprehensive information about the molecular genetic diagnoses and clinical information of individuals with CABP2-associated hearing impairment to support a natural history study.
A patient registry, in both German and English languages, has been established for patients with hereditary hearing impairment due to variants in CABP2. The study is conducted in accordance with the current version of the Declaration of Helsinki. The study protocol and database structure have been approved by the Ethics Committee of the University Medical Center Goettingen.
1,092 studies on the registry are indexed under Hearing Loss; 235 are open to participants now.
This study's planned enrollment of 100 is above the median of 87 across 270 observational studies indexed under Hearing Loss.
Browse Hearing Loss studies →University Medical Center Goettingen is the lead sponsor of 61 studies on the registry; 27 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Individuals with hearing impairment who have a molecular genetic diagnosis involving CABP2
Exclusion Criteria:
Individuals with hearing impairment who have a molecular genetic diagnosis involving CABP2
Diagnostic Test: Molecular genetic testing and audiometry
Genetic testing and audiometry are the interventions of interest
Pure-tone audiometry
Pure tone audiometry is a behavioral hearing test used to measure an individual's hearing threshold levels
Time frame: 1 year, year 1, according to participant consent
Speech audiometry
Speech audiometry is a test or series of tests to determine a patient's ability to discriminate speech sounds and hearing speech or speech in noise
Time frame: 1 year, year 1, according to participant consent
Otoacoustic emission thresholds
Otoacoustic emission thresholds serve as indicators of integrity and function of the outer hair cells in the cochlea
Time frame: 1 year, year 1, according to participant consent
Auditory brainstem response
Auditory brainstem response tests the functional status of the auditory neural pathway
Time frame: 1 year, year 1, according to participant consent
Documents are hosted by the registry — open the source record to download them.
Plan to share: No — Pseudonymized data will be published in publications
Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.
Contact study teamGet an email when the registry record changes — status, dates, results — or when someone posts here.
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Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
University Medical Center Goettingen