CClinicalTrials.gg
Not yet recruitingNCT06632210Updated Jan 2, 2026

Psychological Effects of H Pylori Associated Gastritis

An observational study in H Pylori, sponsored by Assiut University. Not yet recruiting. Per ClinicalTrials.gov, last updated 2026-01-02.

Sponsored by Assiut University · Observational

Study type
Observational
Model
Other
Time perspective
Cross-sectional
Enrollment
130
Sex
All
01

Study summary

The goals of this study

  1. Explore association between psychological factors and Hpylori associated gastritis.
  2. Assess prevalence and severity of psychology symptoms among patients with H pylori associated gastritis and their effects on their life.
  3. Examine relation between demographic and clinical variables .
  4. Effect of eradication of H pylori on psychological status of patients.
Read the detailed description

One of the most prevalant chronic bacterial illness affecting people is it H.plyori infection. it affects at least 50% of people worldwide . it is a human gastrointestinal infection which is believed to be blammed for a number of gastric illness from chronic gastritis up to gastric cancer.

numerous literature data suggest there is strong relation of anxiety disorders, stress or depression to somatic symptoms and this relation can undergo potentialization in case of appearance of pathogenic factors like helicobacter pylori infection , this relation can confirmed with many scientific reports , with the common use of antidepressants and anxiety relieving drugs in duodenal ulcer disease therapy.

The close relationship of gastrointestinal function with brain function and the mental status is known as (gut brain axis).

it has been reported that emotional factors induce changes in gastric physiology that physiological stress induces personality dependant gastric acid secretion changes and avariety of alterations in gastric motility.

. the effect of numerous stress factors which injury mucosa of stomach and modify immunity of the patient so that the patient become more sensitive to be infected with H. Pylori and infection become more aggressive and lead to manifestation of gastritis , duodenitis and gastric ulcer disease.

mental stress is considered a major pathogenic factor for peptic ulcers and it is associated with increasing prevalence of gastric ulcersin patients is with or without H.pyloriinfection.

another study revealed that depression is associated with food related symptoms as nausea and vomiting ,similarly it was showing that gastric information lead to an anxiety and depression like behaviors via neuroendocrine pathways in female not male.

so the investigetors conducted this observational study to determine the most common physiological effect is of H.pylori associated gastritis in patients attending Assiut university hospitals and How to deal with it to improve quality of life.

02

Conditions studied

  • H Pylori
03

In context

Lead sponsor

Assiut University is the lead sponsor of 4,901 studies on the registry; 2,098 are open to participants now.

Of its 13 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

  • all patients with H.Pylori associated gastritis that diagnosed by endoscopy.
  • patients diagnosed by detection of H.Pylori Ag in stool

Inclusion criteria

  1. all patients with H.Pylori associated gastritis that diagnosed by endoscopy.
  2. patients diagnosed by detection of H.Pylori Ag in stool

Exclusion criteria

Exclusion Criteria:

  1. patients did not take antibiotics within last 2 weeks
  2. patients did not take PPI within last 1 month
  3. patients not with acute massive GITbleeding.
  4. patients without eradication of H.Pylor
05

Study design

Observational model
Other
Time perspective
Cross-sectional
Enrollment
130 participants (estimated)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. The aim of this observational study is to Explore correlation between psychological factors and H.Pylori associated gastritis .

    The aim of this observational study is to Explore correlation between psychological factors and H.Pylori associated gastritis .

    Time frame: 2024

07

Study locations

No study locations are listed for this record.

08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 2, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT06632210
Lead sponsor
Assiut University
Responsible party
Ashraf khalifa Darweesh Desokey (Principal investigator, Assiut University) — Principal investigator
First posted
Oct 9, 2024
Start date
Mar 22, 2026 (estimated)
Primary completion
Sep 22, 2026 (estimated)
Completion
Dec 22, 2026 (estimated)
Last update
Jan 2, 2026

Study contacts

Ashraf khalifa Darweesh Desokey Al deep, Master
Contact
ashrafkhalifaaldeep@gmail.com
01018479784
Nabila fayeg Amen, Professor
study director · Assiut University
Mohammed Abozaid Ali, Doctor
study director · Assiut University

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Dec 2025. You cannot join it, but the record below documents what was studied.

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