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CompletedNCT06613828Updated May 1, 2025

Efficacy of Five Strategies To Improve Stroke Awareness in the Spanish-Speaking Population

An interventional study of Mnemonic-Based Educational Training for Stroke Symptom Recognition in Stroke Acute, sponsored by Instituto Mexicano del Seguro Social. Completed at 1 site in Mexico. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-05-01.

Sponsored by Instituto Mexicano del Seguro Social · Not applicable, Interventional, and Screening

From the registry’s dates

  • Registered 5 months after the study started (first participant enrolled Apr 2024, registered Sep 2024).
Phase
Not applicable
Study type
Interventional
Enrollment
435
Allocation
Randomized
Ages
18 Years and older
Sex
All
01

Study summary

The goal of this experimental study is to evaluate the efficacy of five educational strategies for recognizing early symptoms of cerebrovascular disease (CVD) in the general adult population. The main questions it aims to answer are:

  • How effective are the strategies RAPIDO, CORRE, DALE, CAMALEON, and ICTUS 911 in improving the recognition of early CVD symptoms?

Researchers will compare these strategies to determine which one leads to the highest increase in symptom recognition. Participants will receive a brief educational session on one of the five strategies and will:

  • Complete a pre- and post-intervention survey (Stroke Awareness Questionnaire, SAQ).
  • Receive short training on CVD symptoms and the urgency of contacting emergency services.

The primary outcome is the improvement in SAQ scores, and the secondary outcome is the proportion of participants achieving adequate knowledge of CVD symptoms.

02

Conditions studied

  • Stroke Acute

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Keywords

  • Stroke Symptom Recognition
  • Mnemonic-based education
  • stroke awareness
  • Spanish-speaking population
  • Public health intervention
03

In context

Stroke

7,286 studies on the registry are indexed under Stroke; 2,007 are open to participants now.

This study's enrollment of 435 is above the median of 50 across 5,369 interventional studies indexed under Stroke.

Browse Stroke studies →

Lead sponsor

Instituto Mexicano del Seguro Social is the lead sponsor of 124 studies on the registry; 21 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • Age: Participants must be 18 years or older.
  • Consent: Participants must provide informed consent to participate in the study.
  • General Population: Participants from the general public, regardless of their health insurance status or previous medical history (except as specified in exclusion criteria).
  • Language: Participants must be fluent in Spanish, as the educational interventions are based on Spanish-language mnemonic strategies.

Exclusion criteria

Exclusion Criteria:

  • History of Stroke: Participants with a previous diagnosis of cerebrovascular disease (stroke) will be excluded.
  • Cognitive Impairment: Participants who are unable to understand or complete the Stroke Awareness Questionnaire (SAQ) due to cognitive or communication impairments will not be eligible.
  • Incomplete Evaluation: Participants who are unable to complete both the pre- and post-intervention assessments will be excluded from the study.

Elimination Criteria:

  • Lack of Follow-Up: Participants who fail to attend the second evaluation (7 days post-intervention) will be excluded from the final analysis.
  • Withdrawal of Consent: Participants who choose to withdraw from the study at any time will be eliminated from further participation.
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Study design

Phase
Not applicable
Primary purpose
Screening
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
435 participants (actual)

Study arms

  • Experimental
    RAPIDO Strategy Arm

    Participants in this arm receive educational training based on the RAPIDO strategy, an acronym developed to raise awareness of stroke symptoms among the Spanish-speaking community. This strategy is modeled after the English FAST mnemonic and focuses on the rapid identification of stroke symptoms.

    Behavioral: Mnemonic-Based Educational Training for Stroke Symptom Recognition

  • Experimental
    CORRE Strategy Arm

    Participants in this arm are trained using the CORRE strategy, created by a Colombian neurologist. It mirrors the structure of other mnemonic-based interventions and emphasizes the importance of quickly recognizing and acting upon early stroke symptoms.

    Behavioral: Mnemonic-Based Educational Training for Stroke Symptom Recognition

  • Experimental
    DALE Strategy Arm

    Participants in this arm are educated using the DALE strategy, developed in 2012 by researchers at the University of Guadalajara. Similar to the RAPIDO strategy, DALE adapts the FAST mnemonic for the Spanish-speaking population, promoting quick recognition and response to cerebrovascular symptoms.

    Behavioral: Mnemonic-Based Educational Training for Stroke Symptom Recognition

  • Experimental
    CAMALEON Strategy Arm

    In this arm, participants receive training based on the CAMALEON strategy, a mnemonic created in Costa Rica with the support of the pharmaceutical industry. The approach is designed to facilitate the recognition of early stroke symptoms by adapting the FAST mnemonic to Spanish.

    Behavioral: Mnemonic-Based Educational Training for Stroke Symptom Recognition

  • Experimental
    ICTUS 911 Strategy Arm

    Participants in this arm are educated using the ICTUS 911 strategy, which differs from the other four in that it is not directly based on a literal translation of FAST. Instead, it focuses on recognizing stroke symptoms and immediately calling emergency services (911) upon suspicion of a stroke.

    Behavioral: Mnemonic-Based Educational Training for Stroke Symptom Recognition

Interventions

  • BehavioralMnemonic-Based Educational Training for Stroke Symptom Recognition

    This is a Culturally Adapted Mnemonic-Based Educational Strategies for Rapid Stroke Symptom Recognition in the Spanish-Speaking Population. It uses five distinct mnemonic strategies (RAPIDO, CORRE, DALE, CAMALEON, ICTUS 911), each specifically tailored for a Spanish-speaking audience. Aims to improve the recognition of early cerebrovascular disease symptoms, differentiating it from other clinical studies that might focus on different health conditions or target populations. Emphasizes its focus on rapid action by educating participants about stroke symptoms and the importance of contacting emergency services (911).

06

What researchers measure

Primary outcomes

  1. Change in Stroke Awareness Questionnaire (SAQ) Score

    This measure will assess the change in participants\' knowledge of stroke symptoms before and after receiving the educational intervention. The SAQ evaluates awareness of stroke symptoms, risk factors, and appropriate responses to suspected stroke events.

    Time frame: Pre-intervention and 7 days post-intervention.

Secondary outcomes

  1. Proportion of Participants with Adequate Knowledge of Stroke Symptoms

    This outcome measures the proportion of participants who achieve a predetermined \"adequate knowledge\" score on the SAQ, defined as correctly identifying at least 3 stroke symptoms and understanding the need to contact emergency services (911) within 3 hours of symptom onset.

    Time frame: 7 days post-intervention.

07

Study locations

1 site
  • Hospital General de Zona #2
    Aguascalientes, 20190, Mexico
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 1, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT06613828
Lead sponsor
Instituto Mexicano del Seguro Social
Responsible party
Juan Manuel Marquez Romero (Principal Investigator, Instituto Mexicano del Seguro Social) — Principal investigator
First posted
Sep 26, 2024
Start date
Apr 1, 2024
Primary completion
Oct 20, 2024
Completion
Nov 7, 2024
Last update
May 1, 2025

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Apr 2025. You cannot join it, but the record below documents what was studied.

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