An interventional study of Aktiia Bracelet and Healthstats BPro Evo in Blood Pressure, sponsored by Queen Mary University of London. Completed at 1 site in United Kingdom. Open to participants aged 21 Years to 85 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-12-01.
Sponsored by Queen Mary University of London · Not applicable, Interventional, and Other
Wrist worn devices can help record Blood Pressure (BP) throughout the day. As such devices are becoming increasingly affordable, they could help improve awareness, early diagnosis, and treatment of high and uncontrolled BP.
The goal of Continuum BP is to evaluate how BP readings from two different types of wrist-worn cuffless devices available on the market (Aktiia and Healthstats BPro Evo) compare with BP taken using an ambulatory BP monitor which records readings over 24h using a standard upper arm cuff. This interventional study will recruit balanced numbers of male and female participants within different age group, who will sequentially wear the Aktiia Bracelet and the Heathstats BPro Evo for a period of 24h, alongside the cuffed ambulatory BP monitor.
If wrist worn devices are found to measure BP reliably, future research will assess if artificial intelligence can use continuous BP readings from these devices to learn patterns and changes in BP; and develop digital twin models to guide better, more precise BP management for individuals.
Queen Mary University of London is the lead sponsor of 250 studies on the registry; 59 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Participants will wear the Aktiia Bracelet for 24h alongside a cuffed ambulatory BP monitor. Both devices will be recording BP at pre programmed intervals.
Device: Aktiia Bracelet · Device: Spacelabs OnTrak Ambulatory Blood Pressure monitor
Participants will wear the Healthstats BPro Evo smart watch for 24h alongside a cuffed ambulatory BP monitor. Both devices will be recording BP at pre programmed interval
Device: Healthstats BPro Evo · Device: Spacelabs OnTrak Ambulatory Blood Pressure monitor
Wrist worn bracelet with an optical sensor that measures pulse wave characteristics at the wrist.
Wrist worn watch that uses applanation tonometry to measure pulse wave characteristics at the wrist.
Cuffed ambulatory BP monitor that will measure upper arm BP using oscillometry.
Mean Daytime BP Difference
Difference in average Systolic and Diastolic BP measured using ambulatory BP monitor and each device over daytime.
Time frame: Up to 24 hours from device application, using readings from 7am to 11pm.
Mean 24 hours BP Difference
Difference in average Systolic and Diastolic BP measured using ambulatory BP monitor and each device over 24 hours.
Time frame: Up to 24 hours from device application.
Mean Nighttime BP Difference
Difference in average Systolic and Diastolic BP measured using ambulatory BP monitor and each device over night-time.
Time frame: Up to 24 hours from device application, using readings from 11pm to 7am.
Difference in Blood Pressure Variability
Difference in BP variability during daytime and night-time BP recorded by ambulatory BP monitor and each device.
Time frame: Up to 24 hours from device application, using readings from 7am to 11pm to indicate daytime and 11pm to 7am to indicate night-time.
Acceptability of wearing cuffless BP devices using a (simple non-validated) Likert-type device wearability questionnaire.
Measure(s) of acceptability of wearing cuffless BP monitors (compared with wearing ambulatory BP monitor) will include comfort, ability to carry on daily activities, interference with sleep and willingness to use device for long term. These will be reported using descriptive methods for each device, likely as proportions according to the following response options: strongly disagree, disagree, neither agree nor disagree, agree and strongly agree.
Time frame: Up to 24 hours from device application
Plan to share: No — Anonymized data may be provided after publication of findings on reasonable request as per unit's policy.
This study is completed, as verified in Nov 2025. You cannot join it, but the record below documents what was studied.
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Queen Mary University of London