An observational study in Bariatric Surgery and Erectile Dysfunction, sponsored by Jagiellonian University. Completed at 1 site in Poland. Open to male participants aged 18 Years to 65 Years. Per ClinicalTrials.gov, last updated 2024-07-30.
Sponsored by Jagiellonian University · Observational
The prevalence of obesity has risen dramatically worldwide. Beyond its metabolic implications, obesity profoundly impacts sexual health, particularly in males, with erectile dysfunction emerging as a prevalent and distressing comorbidity. Studies show that bariatric surgery alleviates erectile dysfunction. Patients suffering from obesity have lower testosterone levels, which increase after weight-loss surgery. This study aims to investigate the relationship between erectile dysfunction improvement, weight loss and hormonal changes after surgery.
In recent decades, the prevalence of obesity has risen dramatically worldwide, presenting significant public health concerns. Beyond its metabolic implications, obesity profoundly impacts sexual health, particularly in males, with erectile dysfunction (ED) emerging as a prevalent and distressing comorbidity. Obesity exacerbates the risk of ED through complex interplays of physiological and psychological mechanisms. Physiologically, excess adiposity leads to chronic inflammation, endothelial dysfunction, and hormonal imbalances, all of which contribute to impaired vascular health and reduced testosterone levels, key factors in erectile function. Psychologically, body image dissatisfaction and decreased self-esteem associated with obesity can exacerbate sexual performance anxiety and further contribute to ED. Bariatric surgery is an established treatment method for long-term weight loss which also alleviates symptoms of diabetes, hypertension, and other weight-related comorbidities.
683 studies on the registry are indexed under Erectile Dysfunction; 117 are open to participants now.
This study's enrollment of 135 is close to the median of 130 across 115 observational studies indexed under Erectile Dysfunction.
Browse Erectile Dysfunction studies →Jagiellonian University is the lead sponsor of 156 studies on the registry; 34 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Male patients undergoing weight loss surgery at high volume bariatric centre. Male patiens who are sexually active
Exclusion Criteria:
Male patients undergoing bariatric surgery
Procedure: Sleeve gastrectomy
Each patient undergoes bariatric surgery. Each patient is diagnosed before surgery for erectile dysfunction. Similar tests are done 1 year after
The International Index of Erectile Function score
6 questions from IIEF official questionnare. Each question is score 1-5. Erectile dysfunction (ED) assessed using a validated tool Patient who scored \<25 points were considered for further analysis. Each patient was categorized into severity: 25-30 no ED, 19-24 mild ED, 13-18 mild to moderate ED, 7-12 moderate ED, 0-6 severe ED. After follow-up, patients with prior ED (\<25 IIEF) were assigned to three groups: 1 - no improvement, 2 - symptom alleviation (change in severity category), 3 - ED remission
Time frame: immediately before surgery and one year after
Weight loss results
weight loss (WL) in kg
Time frame: one year after surgery
percentage of excess weight loss (%EWL)
Weight loss results
Time frame: one year after surgery
percentage of total weight loss (%TWL)
Weight loss results
Time frame: one year after surgery
Testoreone (nmol/l)
Laboratory test using blood samples
Time frame: immediately before surgery and one year after
Sex hormone binding (nmol/l)
Laboratory test using blood samples
Time frame: immediately before surgery and one year after
Estradiol (pmol/l)
Laboratory test using blood samples
Time frame: immediately before surgery and one year after
luteinizing hormone (mIU/ml)
Laboratory test using blood samples
Time frame: immediately before surgery and one year after
Plan to share: No
This study is completed, as verified in Jul 2024. You cannot join it, but the record below documents what was studied.
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Jagiellonian University