An interventional study of full-spectrum light exposure and specific spectrum absence light exposure in Full Spectrum, sponsored by Zhongshan Ophthalmic Center, Sun Yat-sen University. Not yet recruiting. Open to participants aged 7 Years to 45 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2024-07-15.
Sponsored by Zhongshan Ophthalmic Center, Sun Yat-sen University · Not applicable, Interventional, and Prevention
Previous studies have shown that the spectrum of light influences myopia. LED lights with a partially absent light spectrum increase the risk of myopia progression compared to LEDs with a full spectrum, potentially mediated by the excitability of the parasympathetic nervous system. This study intends to compare pupil size and area, as well as parameters regulated by the autonomic nervous system (such as skin bioelectrical activity and heart rate), between LEDs with a full visible spectrum and LEDs with a partially absent spectrum around 470nm and 730nm. We aim to elucidate the physiological mechanism underlying the effect of light spectrum on pupil changes and myopia.
Zhongshan Ophthalmic Center, Sun Yat-sen University is the lead sponsor of 159 studies on the registry; 77 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Age 7-45 years 2. Able to wear multi-channel physiological measurement devices and cooperate with experimental procedures.
Exclusion Criteria:
History of diseases affecting autonomic nervous system function, such as depression and anxiety.
Subjects were asked to stay in a resting state for 5 minutes in a dark room, then turn on the full-spectrum light and adapt to the light environment for 5 minutes, and then take measurements for 5 minutes. After wash-out in the dark room for 5 minutes, change the light to ordinary LED lamp and repeat the above test steps for measurement.
Other: full-spectrum light exposure
Subjects were asked to stay in a resting state for 5 minutes in a dark room, then turn on the ordinary LED lamp and adapt to the light environment for 5 minutes, and then take measurements for 5 minutes. After wash-out in the dark room for 5 minutes, change the light to full-spectrum light and repeat the above test steps for measurement.
Other: specific spectrum absence light exposure
Subjects will stay in a room with full spectrum light for 5 minutes. After 5 minutes wash-out period, altenate to the other arm.
Subjects will stay in a room with ordinary LED light for 5 minutes. After 5 minutes wash-out period, altenate to the other arm.
pupil size
The pupil diameter is measured in real-time using the Eyelink Portable Duo eye tracker.
Time frame: 5 minutes
Skin conductance response
Rapidly changing and short-duration skin surface potentials measured in real-time using the Biopac MP160 multi-channel physiological recorder.
Time frame: 5 minutes
Respiratory movement
The amplitude of respiratory movements measured in real-time using the Biopac MP160 multi-channel physiological recorder.
Time frame: 5 minutes
Pulse pressure waveform
The amplitude of respiratory movements measured in real-time using the Biopac MP160 multi-channel physiological recorder.
Time frame: 5 minutes
Spherical equivalent refraction
Measured with autorefractor and defined as the sum of spherical power and half of the cylinder power.
Time frame: 5 minutes
Uncorrected visual acuity
Visual acuity without refractive correction.
Time frame: 5 minutes
Axial length
Uncorrected visual acuity: Visual acuity without refractive correction.
Time frame: 5 minutes
Corneal curvature
Anterior corneal curvature measured by the Pentacam corneal topographer
Time frame: 5 minutes
No study locations are listed for this record.
This study is not yet recruiting, as verified in Jul 2024. You cannot join it, but the record below documents what was studied.
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Zhongshan Ophthalmic Center, Sun Yat-sen University