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Not yet recruitingNCT06477497Updated Jun 27, 2024

The Application of Comprehensive Prevention and Treatment Strategy of Placenta Accreta Spectrum Disorders

An observational study in Placenta Accreta Spectrum, sponsored by Peking Union Medical College Hospital. Not yet recruiting. Open to female participants, including healthy volunteers. Per ClinicalTrials.gov, last updated 2024-06-27.

Sponsored by Peking Union Medical College Hospital · Observational

From the registry’s dates

  • Primary completion was expected by Nov 2025, 11 months ago, but the record still lists the study as not yet recruiting.
Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
33
Sex
Female
01

Study summary

Placenta accreta spectrum (PAS) disorders are pathological attachment of the placenta to myometrium, where trophoblastic cells invade the uterine placental interface. PAS can lead to severe postpartum hemorrhage or even maternal death. Prenatal diagnosis of PAS is essential for optimal obstetric management to improve the pregnancy outcomes. However, in some low resource regions in China, less than 20% PAS are detected before delivery.

To explore the feasibility and universality of the bundled prevention and treatment strategy for placenta accreta spectrum disorders in different levels of medical institutions, and to investigate its effectiveness in improving the specialized disease management capabilities of medical institutions at all levels. We will conduct a regional, cluster-randomized trial to assess a multicomponent PAS management strategy to improve the prepartum detection rate of PAS.

02

Conditions studied

  • Placenta Accreta Spectrum

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Keywords

  • placenta accreta spectrum disorders
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In context

Placenta Accreta

150 studies on the registry are indexed under Placenta Accreta; 40 are open to participants now.

This study's planned enrollment of 33 is below the median of 87 across 78 observational studies indexed under Placenta Accreta.

Browse Placenta Accreta studies →

Lead sponsor

Peking Union Medical College Hospital is the lead sponsor of 1,155 studies on the registry; 475 are open to participants now.

Of its 5 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
Female
Accepts healthy volunteers
Yes
Sampling method
Probability sample

Study population

Pregnant women with placenta accreta spectrum disorders

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Pregnant women who have regular prenatal examination at the research hospitals
  • Pregnant women diagnosed with PAS before or after delivery

Exclusion criteria

Exclusion Criteria:

  • Pregnant women who have never been diagnosed with placental implantation disease throughout the pregnancy
  • Pregnant women who were lost to follow-up during the study period
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Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
33 participants (estimated)
Patient registry
No

Groups and cohorts

  • study group

    Theoretical training, technical supporting and standardized referral process

  • control group

    usual care

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What researchers measure

Primary outcomes

  1. antepartum diagnosis rate of PAS

    Time frame: through study completion, an average of 1.5 year

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Study locations

No study locations are listed for this record.

08

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Start is estimated for Jul 2024; primary completion for Nov 2025, 16 months later.

Of 34 observational studies under Placenta Accreta, half reached primary completion within 18 months of starting (the median), counting those still running; a quarter within 12 and three quarters within 35. This study's planned 16 months is below that.

How these figures are worked out, and which studies are left out of them.

Registered
Jun 4, 2024
First posted
Jun 27, 2024
StartEst.
Jul 1, 2024
Primary completionEst.
Nov 30, 2025
CompletionEst.
Nov 30, 2025
Last update
Jun 27, 2024
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Jun 27, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT06477497
Collaborators
National Key Research and Development Program of China
Responsible party
Sponsor
First posted
Jun 27, 2024
Start date
Jul 1, 2024 (estimated)
Primary completion
Nov 30, 2025 (estimated)
Completion
Nov 30, 2025 (estimated)
Last update
Jun 27, 2024

Study contacts

Jinsong Gao
Contact
gaojingsong@pumch.cn
0861069156225

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Jun 2024. You cannot join it, but the record below documents what was studied.

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Discussion

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