CClinicalTrials.gg
CompletedNCT06397716AIACUpdated Apr 23, 2026

Public Health Initiative on Alcohol Flushing

An interventional study of ALDH2 Genotyping in Alcohol Toxicity, sponsored by Stanford University. Completed at 1 site in United States. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-04-23.

Sponsored by Stanford University · Not applicable, Interventional, and Prevention

Phase
Not applicable
Study type
Interventional
Enrollment
70
Allocation
Randomized
Ages
18 Years and older
Sex
All
01

Study summary

The overall aim of the study is to raise awareness of alcohol flushing and its health risks to the general population.

The primary objective is to see if spreading awareness of the health risks of alcohol flushing and understanding personalized genotype information will lead to changes in alcohol consumption behavior.

02

Conditions studied

  • Alcohol Toxicity

Keywords

  • Alcohol Flushing
03

In context

Lead sponsor

Stanford University is the lead sponsor of 2,117 studies on the registry; 425 are open to participants now.

Of its 259 completed or terminated interventional studies of FDA-regulated products, 197 (76%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • Adult age over 18
  • Native English speaker

Exclusion criteria

Exclusion Criteria:

  • None
05

Study design

Phase
Not applicable
Primary purpose
Prevention
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
70 participants (actual)

Study arms

  • Experimental
    Genotype Revealed

    Subjects with ALDH2 mutation will be notified of positive genotype results after testing completed.

    Genetic: ALDH2 Genotyping

  • Placebo comparator
    Gentoype Not-Revealed

    Subjects with ALDH2 mutation will not be notified of positive genotype results until after study completed.

    Genetic: ALDH2 Genotyping

Interventions

  • GeneticALDH2 Genotyping

    Cheek swab for PCR testing of ALDH2 genotype.

06

What researchers measure

Primary outcomes

  1. Alcohol Flushing Awareness

    Alcohol flushing reaction awareness questionnaire, scale from 0 to 4, higher score is better outcome

    Time frame: Baseline, 1 month, 3 month

  2. Alcohol Consumption Habits 1

    Number of days alcohol was consumed in past 30 days

    Time frame: Baseline, 1 month, 3 month

  3. Alcohol Consumption Habits 2

    Number of days 2 or more drinks of alcohol was consumed in past 30 days

    Time frame: Baseline, 1 month, 3 month

  4. Alcohol Consumption Habits 3

    Average number of alcohol consumed on days alcohol was consumed

    Time frame: Baseline, 1 month, 3 month

  5. Alcohol Consumption Habits 4

    Largest number of drinks of alcohol consumed in one sitting

    Time frame: Baseline, 1 month, 3 month

07

Study locations

1 site
  • Stanford University
    Palo Alto, California 94304, United States
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Apr 23, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT06397716
Lead sponsor
Stanford University
Collaborators
Stanford Center for Asian Health Research and Education
Responsible party
Kevin Chang (Clinical Assistant Professor of Medicine, Stanford University) — Principal investigator
First posted
May 3, 2024
Start date
Apr 25, 2024
Primary completion
Apr 25, 2024
Completion
Apr 25, 2024
Last update
Apr 23, 2026

Study contacts

Kevin Chang, MD
principal investigator · Stanford University

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Apr 2026. You cannot join it, but the record below documents what was studied.

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