An Early Phase 1 interventional study of Testosterone injection and Testosterone gel in Healthy, sponsored by Sports Medicine Research and Testing Laboratory. Completed at 1 site in United States. Open to male participants aged 18 Years to 60 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2024-12-03.
Sponsored by Sports Medicine Research and Testing Laboratory · Early Phase 1, Interventional, and Other
Testosterone abuse is extremely prevalent in athletes globally and especially in the United States professional sporting leagues
Because human bodies make testosterone naturally, it can be difficult to determine whether the testosterone in your body is natural or if it came from administering testosterone. Currently, testosterone abuse by athletes is detected by anti-doping laboratories in urine samples and use can also be inferred by testing blood samples. As a pharmaceutical preparation, testosterone is available to administer to your body in different ways. However, due to lack of controlled data on the various preparations of testosterone administrations related to the anti-doping field, this study id designed to look at five different testosterone preparations delivered three different ways and how they compare to each other in terms of anti-doping detection and how long they will be in circulation in your body.
Sports Medicine Research and Testing Laboratory is the lead sponsor of 3 studies on the registry; none are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
The participant will receive a single injection of one of three types of testosterone in phase one. In phase two the participant will receive two weeks of either a daily skin cream or a twice-daily pill to swallow.
Drug: Testosterone injection · Drug: Testosterone gel
The participant will receive a single injection of one of three types of testosterone in phase one. In phase two the participant will receive two weeks of either a daily skin cream or a twice-daily pill to swallow.
Drug: Testosterone injection · Drug: Testosterone Oral
A single injection of testosterone
Also known as: testosterone cipionate, enanthate,or propionate
A daily dose of testosterone gel
Also known as: testosterone transdermal
A twice-daily pill of testosterone pill to swallow
Also known as: testosterone undecanoate
Detection windows of testosterone administered via injection, oral and skin cream.
Changes in urinary testosterone/epitestosterone ratio after administration of testosterone in injection, oral and cream
Time frame: 12 weeks
Changes in serum concentration of testosterone
Changes in serum concentrations of testosterone in injection, oral and cream administration of testosterone
Time frame: 12 weeks
Changes in serum concentration of androstenedione
Changes in serum concentrations of androstenedione in injection, oral and cream administration of testosterone
Time frame: 12 weeks
Changes in serum concentration of luteinizing hormone
Changes in serum concentrations of luteinizing hormone after injection, oral and cream administration of testosterone
Time frame: 12 weeks
Direct detection of testosterone esters
Direct detection of testosterone esters
Time frame: 12 weeks
Plan to share: No
No publications or documents are linked to this record.
This study is completed, as verified in Nov 2024. You cannot join it, but the record below documents what was studied.
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Sports Medicine Research and Testing Laboratory