An observational study in Anesthesia Brain Monitor, Sufentanil and Target Controlled Infusion, sponsored by University of Padova. Completed at 1 site in Italy. Open to female participants aged 18 Years to 90 Years. Per ClinicalTrials.gov, last updated 2024-10-24.
Sponsored by University of Padova · Observational
Sufentanil Target Controlled infusion (TCI, Gepts model) effects on Neuromonitoring during Total Intravenous Anesthesia (TIVA) with Propofol TCI (Eleveld model) has not been investigate yet.
Authors aim to investigate its effect on Patient State index (PSi), the power spectrum EEG, the Analgesia Nociception Index (ANI) nad pupillometry values during maintenance durin TIVA-TCI with Propofol and Sufentanil.
Sufentanil Target Controlled infusion (TCI, Gepts model) effects on Neuromonitoring during Total Intravenous Anesthesia (TIVA) with Propofol TCI (Eleveld model) has not been investigate yet.
Authors aim to investigate its effect on Patient State index (PSi), the power spectrum EEG, the Analgesia Nociception Index (ANI) and pupillometry values during maintenance during TIVA-TCI with Propofol and Sufentanil.
University of Padova is the lead sponsor of 210 studies on the registry; 42 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Women undergoing brast cancer surgery with general anesthesia with Propofol and SufentanilTCI will be recruited
Exclusion Criteria:
Effects of Sufentanil on Patient State index (PSi) during stable Propofol general anesthesia
Evaluate if sufentanil variations during general anesthesia has an impact on the PSi values
Time frame: PSi values and Sufentanil Target Controlled Infusion (TCI) concentrations will be monitored during all the time of surgery
Effects of Sufentanil on Electroencephalogram (EEG) power spectrum during stable Propofol general anesthesia
Evaluate if sufentanil variations during general anesthesia has an impact on the EEG power spectrum
Time frame: EEG power spectrum and Sufentanil Target Controlled Infusion (TCI) concentrations will be monitored during all the time of surgery
Effects of Sufentanil on Analgesia Nociception Index (ANI) during stable Propofol general anesthesia
Evaluate if sufentanil variations during general anesthesia has an impact on the ANI values
Time frame: ANI values and Sufentanil Target Controlled Infusion (TCI) concentrations will be monitored during all the time of surgery
Analgesia Nociception Index (ANI) values and postoperative pain
Evaluate if different ANI values at the same Sufentanil concentrations has an impact on postoperative pain
Time frame: Numeric Rating Scale (NRS) will be evaluated after the end of surgery and 24 hours after the end of surgery and compared to ANI values after 24 hours
Patient State Index (PSi) values and postoperative delirium
Evaluate if different PSi values at the same Sufentanil concentrations has an impact on postoperative pain
Time frame: Confusion assessment method (CAM) test for delirium will be performed after the end of surgery and compared to PSi values after 24 hours
Analgesia Nociception Index (ANi) values and postoperative nausea and vomiting
Evaluate if different ANi values at the same Sufentanil concentrations has an impact on postoperative nausea and vomiting.
Time frame: Nausea and vomiting occurrence will be detected hours atend of surgery and compared to ANI values after 24 hours
Plan to share: Undecided
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University of Padova