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CompletedNCT06349707VirCoV+Updated Feb 18, 2025

Multiplex PCR for Severe Respiratory Infections During the COVID-19 Pandemic

An observational study in Viral Pneumonia, sponsored by Central Hospital, Nancy, France. Completed at 1 site in France. Per ClinicalTrials.gov, last updated 2025-02-18.

Sponsored by Central Hospital, Nancy, France · Observational

Study type
Observational
Model
Ecologic or community
Time perspective
Retrospective
Enrollment
18
Sex
All
01

Study summary

The hypothesis was that a retrospective investigation of the molecular virological tests in a University hospital could be informative, with the aim to identify non-COVID-19 respiratory viruses during the circulation of SARS-CoV-2, according to systematic population data for public health knowledge.

Read the detailed description

The hypothesis was that a retrospective investigation of the molecular virological tests in a University hospital could be informative, with the aim to identify non-COVID-19 respiratory viruses during the circulation of SARS-CoV-2, according to systematic population data for public health knowledge:

  • the main goal was to perform a retrospective investigation of the molecular virological tests in a University hospital, in order to identify non-COVID-19 respiratory viruses from the beginning of 2021 to mid-2022 during the circulation of SARS-CoV-2, for public health knowledge;
  • the secondary aim was to retrospectively analyze, for a small subgroup of patients from an intensive care unit, the files of patients with positive molecular virological tests for non-COVID-19 respiratory viruses from the beginning of 2021 to mid-2022, reporting the following standard-of-care data: (i) the identification of the viruses, (ii) bioclinical features, (iii) medical impact of virological results in real life.
02

Conditions studied

  • Viral Pneumonia

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Keywords

  • respiratory virus
03

In context

Pneumonia, Viral

146 studies on the registry are indexed under Pneumonia, Viral; 11 are open to participants now.

This study's enrollment of 18 is below the median of 210 across 54 observational studies indexed under Pneumonia, Viral.

Browse Pneumonia, Viral studies →

Lead sponsor

Central Hospital, Nancy, France is the lead sponsor of 797 studies on the registry; 188 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

18 Intensive Care Unit (ICU)-patients, from the whole population of patients who were hospitalized for respiratory infections from early 2021 to mid-2022 in Nancy University hospital, France:

  • from the results of the multiplex FilmArrays PCR tests carried out during the 18 months of the study;
  • for the ICU files, 18 patients positive for virus by the FilmArray Pneumonia test: ICU patients (or representatives) informed of the data collection that can be used for research (ICCA db)

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • For adult patients, or minors 'via' parents, able to give consent - 18 intensive care patients

Exclusion criteria

Exclusion Criteria:

  • Non-inclusion in case of refusal
05

Study design

Observational model
Ecologic or community
Time perspective
Retrospective
Enrollment
18 participants (actual)
Patient registry
No

Groups and cohorts

  • 18 ICU-patients group

    18 ICU (Intensive Care Unit)-patients group, from the whole population of patients (1,614) who were hospitalized for respiratory infections from early 2021 to mid-2022 in Nancy University hospital, France.

    Other: other: Observational

Interventions

  • Otherother: Observational

    For 18 ICU patients, retrospective collection of routine bioclinical database (ICCA db)

06

What researchers measure

Primary outcomes

  1. Occurrence of positive viral PCR assays (not COVID-19) from hospitalizations for respiratory infections.

    Number of patients with positive virological molecular tests (multiplex respiratory panels) from the beginning of 2021 to mid-2022, with the nature of the viruses detected and the chronology of occurrence of positive tests.

    Time frame: 18 months, retrospectively

Secondary outcomes

  1. Real-life features of patients in Intensive care (from the whole population - Outcome 1) with positive viral PCR during infectious pneumonia.

    For the group of patients in Intensive Care: * (i) number of positive molecular virological tests detecting respiratory viruses by FilmArray Pneumonia test * (ii) associated bioclinical data * (iii) medical impact of virological results in real life - progression of the infection and duration of thehospitalization.

    Time frame: 18 months, retrospectively

07

Study locations

1 site
  • Schvoerer
    Vandœuvre-lès-Nancy, 54511, France
08

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Ran from Apr 2024 to primary completion in May 2024, 1 month.

How these figures are worked out, and which studies are left out of them.

Registered
Apr 4, 2024
First posted
Apr 5, 2024
StartActual
Apr 1, 2024
Primary completionActual
May 1, 2024
CompletionActual
Jun 1, 2024
Last update
Feb 18, 2025
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Feb 18, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT06349707
Responsible party
Sponsor
First posted
Apr 5, 2024
Start date
Apr 1, 2024
Primary completion
May 1, 2024
Completion
Jun 1, 2024
Last update
Feb 18, 2025

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Apr 2024. You cannot join it, but the record below documents what was studied.

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