An interventional study of Acupressure Therapy and Educational Intervention in Hematopoietic and Lymphatic System Neoplasm and Malignant Solid Neoplasm, sponsored by Mayo Clinic. Completed at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-10-29.
Sponsored by Mayo Clinic · Not applicable, Interventional, and Supportive care
This clinical trial evaluates whether acupressure is helpful to reduce anxiety related to chemotherapy. Anxiety is experienced by many patients with cancer. Anxiety can be related to chemotherapy and may contribute to other symptoms, such as nausea and poor quality of life. Some patients diagnosed with cancer express interest in non-medicinal ways to manage symptoms. Acupressure is a noninvasive intervention that can be used for many different symptoms. Acupressure is well tolerated with minimal reports of adverse reactions, making it a good choice for patients with cancer. This study may help researchers learn whether acupressure is useful for managing anxiety in patients undergoing chemotherapy.
PRIMARY OBJECTIVES:
I. Evaluate the feasibility of a nurse- and patient-applied acupressure intervention for patients with anxiety associated with active cancer-directed therapy.
II. Patient-reported changes in acute anxiety associated with both the nurse and self-led acupressure interventions will be ascertained.
OUTLINE:
Patients undergo acupressure over 15-120 seconds at a time for up to 15 minutes. After completion of the session, patients may optionally receive an education session on using acupressure at home.
After completion of study intervention, patients who opted to receive education about using acupressure at home are followed up at 1 week.
Mayo Clinic is the lead sponsor of 3,218 studies on the registry; 670 are open to participants now.
Of its 445 completed or terminated interventional studies of FDA-regulated products, 313 (70%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Patients undergo acupressure over 15-120 seconds at a time for up to 15 minutes. After completion of the session, patients may optionally receive an education session on using acupressure at home.
Procedure: Acupressure Therapy · Other: Educational Intervention · Other: Electronic Health Record Review · Other: Questionnaire Administration
Undergo acupressure
Also known as: Acupressure, Ischemic Compression
Receive education session about using acupressure at home
Also known as: Education for Intervention, Intervention by Education, Intervention through Education, Intervention, Educational
Ancillary studies
Ancillary studies
Number of patients approached about undergoing acupressure intervention (Feasibility)
Assessed by the number of patients approached about undergoing acupressure intervention.
Time frame: Up to 1 year
Number of patients interested in the initial acupressure intervention in the chemotherapy unit (Feasibility)
Assessed by the number of patients who express interest in the initial acupressure intervention in the chemotherapy unit.
Time frame: Up to 1 year
Number of patients interested in the home acupressure intervention (Feasibility)
Assessed by the number of patients who express interest in the home acupressure intervention.
Time frame: Up to 1 year
Time taken for each nurse-led acupressure intervention in the chemotherapy unit (Feasibility)
Assess by the time recorded for ach nurse-led acupressure intervention in the chemotherapy unit.
Time frame: Up to 1 year
Patient-reported changes in acute anxiety
Assessed with a brief anxiety questionnaire that inquires about the three different domains of anxiety: cognitive symptoms, emotional symptoms, and physical symptoms. Seven questions are answered using 11-point (0-10) scales with different values assigned to the scale per question (e.g. 0=no anxiety/10=worst possible anxiety or 0=strongly disagree/10=strongly agree).
Time frame: At baseline, after a one-time nurse-administered acupressure session, and after one week of self-administered acupressure sessions
This study is completed, as verified in Oct 2025. You cannot join it, but the record below documents what was studied.
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