An interventional study of Drug: ciprofol injection in Anesthesia, sponsored by Le Yu. Recruiting at 1 site in China. Open to participants aged 55 Years to 75 Years. Per ClinicalTrials.gov, last updated 2024-03-15.
Sponsored by Le Yu · Not applicable, Interventional, and Other
Ciprofol, a novel intravenous general anesthetic with a chemical structure akin to propofol, boasts significantly enhanced potency. It offers a rapid onset, reduced incidence of injection pain, and minor impact on the cardiovascular system. However, clinical research regarding ciprofol's use for anesthesia induction in cardiac surgery remains limited.
Le Yu is the lead sponsor of 3 studies on the registry; 3 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Drug: Drug: ciprofol injection
Drug: Drug: ciprofol injection
Patients in ciprofol group 0.3 mg/kg ciprofol for induction of anesthesia
Mean arterial pressure
an average blood pressure in an individual during a single cardiac cycle
Time frame: 1 second before induction of anesthesia (T1)
Mean arterial pressure
an average blood pressure in an individual during a single cardiac cycle
Time frame: 1 second before tracheal intubation (T2)
Mean arterial pressure
an average blood pressure in an individual during a single cardiac cycle
Time frame: 1 minute after tracheal intubation (T3)
Mean arterial pressure
an average blood pressure in an individual during a single cardiac cycle
Time frame: 5 minutes after tracheal intubation (T4)
Heart beats
the number of times each minute that heart beats
Time frame: 1 second before induction of anesthesia (T1)
Heart beats
the number of times each minute that heart beats
Time frame: 1 second before tracheal intubation (T2)
Heart beats
the number of times each minute that heart beats
Time frame: 1 minute after tracheal intubation (T3)
Heart beats
the number of times each minute that heart beats
Time frame: 5 minutes after tracheal intubation (T4)
Oxygenation index
a calculation used in intensive care medicine to measure the fraction of inspired oxygen (FiO2) and its usage within the body.
Time frame: 1 second before induction of anesthesia (T1)
Oxygenation index
a calculation used in intensive care medicine to measure the fraction of inspired oxygen (FiO2) and its usage within the body.
Time frame: 10 minutes after tracheal intubation (T5)
Injection pain
Pain at the injection site when injecting the drug（Evaluation with Visual Analogue Scale）
Time frame: During procedure (When injecting the drug, ask the subject if the injection site is painful)
Plan to share: Undecided
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