An observational study in Idiopathic Short Stature, sponsored by BioMarin Pharmaceutical. Recruiting at 38 sites in United States. Open to participants aged 2 Years to 16 Years. Per ClinicalTrials.gov, last updated 2026-06-23.
Sponsored by BioMarin Pharmaceutical · Observational
Study 111-903 will generate baseline growth data in children with ISS by collecting growth measurements and other variables of interest.
BioMarin Pharmaceutical is the lead sponsor of 112 studies on the registry; 13 are open to participants now.
Of its 17 completed or terminated interventional studies of FDA-regulated products, 12 (71%) have results posted.
Counted across the registry records on this site, refreshed daily.
The study population will include up to 600 pediatric individuals with Idiopathic Short Stature.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
A drug or device being studied in a clinical trial.
It may be new, or already approved and being studied for another use, dose or form. Criteria often leave out people who took part in another study of one within a recent period, commonly 30 days or five half-lives.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Investigational drug or device
A drug or device being studied in a clinical trial.
It may be new, or already approved and being studied for another use, dose or form. Criteria often leave out people who took part in another study of one within a recent period, commonly 30 days or five half-lives.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Change in annualized growth velocity (AGV)
Time frame: Every 6 months through end of study, up to 15 years
Change in Height Z-score
Time frame: Every 6 months through end of study, up to 15 years
Change in Standing Height
Time frame: Every 6 months through end of study, up to 15 years
Change in BMI
Time frame: Every 6 months through end of study, up to 15 years
Change in BMI Z-score
Time frame: Every 6 months through end of study, up to 15 years
Frequency of event rates of medical events of interest
Time frame: Every 6 months through end of study, up to 15 years
Frequency of Serious Medical Events
Time frame: Every 6 months through end of study, up to 15 years
Association between specific variants and growth velocity
Time frame: Every 6 months through end of study, up to 15 years
Association between other health outcomes directly related to short stature
Time frame: Every 6 months through end of study, up to 15 years
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Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.
Contact study teamGet an email when the registry record changes — status, dates, results — or when someone posts here.
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