An observational study in Heart Failure With Preserved Ejection Fraction, sponsored by Istituto Auxologico Italiano. Recruiting at 1 site in Italy. Per ClinicalTrials.gov, last updated 2025-08-03.
Sponsored by Istituto Auxologico Italiano · Observational
Diagnosing heart failure with preserved ejection fraction (HFpEF) in patients complaining exertional breathlessness can be challenging: diagnostic algorithms and scores have low sensitivity, and ageing-associated comorbidities can complicate the interpretation of symptoms. Thus, exercise right heart catheterization (RHC) or invasive cardiopulmonary exercise test (iCPET) have been advocated as gold-standard methods for HFpEF diagnosis. However, exercise RHC and iCPET are still not widely standardized methods, with results mainly coming from US cohorts (that may differ from Italian cohorts), and other provocative tests (e.g. non-invasive CPET, passive leg raising) may offer complementary diagnostic information.
Istituto Auxologico Italiano is the lead sponsor of 196 studies on the registry; 78 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Consecutive patients referred to the Dyspnea and Pulmonary Hypertension Center for suspicion of HF, PH or unexplained dyspnea
Exclusion Criteria:
exercise test
Mortality
Incidence of mortality
Time frame: 5 years
Hospitalization for heart failure
Incidence of hospitalization for heart failure
Time frame: 5 years
Atrial fibrillation
Incidence of atrial fibrillation
Time frame: 5 years
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Istituto Auxologico Italiano