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RecruitingNCT06291389Updated Jan 6, 2026

Intraoperative Peak Airway Pressure Changes on Postoperative Pulmonary Function After Muscle Plication

An observational study in Abdominal Compartment Syndrome, sponsored by Al-Azhar University. Recruiting at 1 site in Egypt. Open to participants aged 20 Years to 50 Years. Per ClinicalTrials.gov, last updated 2026-01-06.

Sponsored by Al-Azhar University · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
120
Ages
20 Years to 50 Years
Sex
All
01

Study summary

An abdominal panniculus excision procedure is known as an abdominoplasty (panniculectomy). Musculofascial plication is a crucial aspect of abdominoplasty, especially for patients with significant divarication of the recti muscles. This study aimed to evaluate the effect of intraoperative changes in peak airway pressure (PAP) after muscle plication on postoperative pulmonary function.

Read the detailed description

Musculofascial plication is a crucial aspect of abdominoplasty, especially for patients with significant divarication of the recti muscles. This surgical procedure involves the removal of surplus skin and fat around the abdomen, known as panneculectomy, and the anterior abdominal wall muscles' laxity being tightened. This study aimed to elucidate the effect of intraoperative changes in PAP after muscle plication on postoperative pulmonary function.

02

Conditions studied

  • Abdominal Compartment Syndrome
03

Who can participate

Ages eligible
20 Years to 50 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

age ranged between 20 and 50 years old,- American Society of Anesthesiologists (ASA) physical status classification I and came for abdominoplasty operation

Inclusion criteria

  • age ranged between 20 and 50 years old,
  • American Society of Anesthesiologists (ASA) physical status classification I
  • came for abdominoplasty operation

Exclusion criteria

Exclusion Criteria:

  • anemia or hemoglobin levels below 11g/dl
  • bleeding problems
  • cardiovascular disorders
  • restrictive and obstructive respiratory disease
  • abdominoplasty without plication.
04

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
120 participants (estimated)
Patient registry
No
05

What researchers measure

Primary outcomes

  1. Intraoperative peak airway pressure (PAP)

    Intraoperative peak airway pressure (PAP) will be observed Pre-plication, Post- plication in supine position and Post- plication in semi-sitting position

    Time frame: 4 hours

Secondary outcomes

  1. Duration of oxygen therapy

    The duration of oxygen therapy will be recorded

    Time frame: 1 week

  2. Post operative Tidal Volume (Vt) (Measured by spirometer)

    The post operative Tidal Volume (Vt) will be measured by spirometer and will be recorded

    Time frame: 24 hours postoperatively

  3. Post operative Respiratory Rate (RR)

    The Post operative Respiratory Rate (RR) will be recorded

    Time frame: 24 hours postoperatively

  4. Hospital stay.

    The Duration of hospital stay will be recorded

    Time frame: 1 week

06

Study locations

1 of 1 sites recruiting
  • Neveen Kohaf
    Tanta, Egypt 11865, Egypt
    • Haney Bauiomy · Principal investigator
    • Ahmed Abosakaya · Principal investigator
    Recruiting
07

References and documents

Individual participant data

Plan to share: Yes — Data will be shared upon resealable request from principle investigator

Supporting information: Study protocol, Sap

No publications or documents are linked to this record.

08

Registry details

Key details

Study ID
NCT06291389
Lead sponsor
Al-Azhar University
Collaborators
Benha University
Responsible party
Neveen Abd El Maksoad Kohaf (Lecturer of Clinical Pharmacy, Al-Azhar University) — Principal investigator
First posted
Mar 4, 2024
Start date
Mar 10, 2024
Primary completion
Dec 15, 2026 (estimated)
Completion
Dec 15, 2026 (estimated)
Last update
Jan 6, 2026

Study contacts

Neveen Kohaf, Ph.D
Contact
nevenabdo@azhar.edu.eg
+201060383012
Neveen Kohaf, ph.d
principal investigator · Al-Azhar University

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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