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RecruitingNCT06190288AdvantAGEUpdated Feb 2, 2024

AdvantAGE: Implementation and Evaluation of an Interprofessional Tranistional Care Model for Frail Older Adults

An interventional study of Transitional care model in Transitional Care, Multimorbidity and Geriatric Care, sponsored by Thekla Brunkert. Recruiting at 1 site in Switzerland. Open to participants aged 65 Years and older. Per ClinicalTrials.gov, last updated 2024-02-02.

Sponsored by Thekla Brunkert · Not applicable, Interventional, and Health services research

From the registry’s dates

  • Primary completion was expected by Jun 2026, 3 months ago, but the record still lists the study as recruiting.
  • Started Jan 2024; still recruiting 2 years 9 months later.
Phase
Not applicable
Study type
Interventional
Enrollment
250
Allocation
Not applicable
Ages
65 Years and older
Sex
All
01

Study summary

This clinical trial at the University Department of Geriatric Medicine FELIX Platter in Basel, Switzerland, is designed to evaluate a new transitional care model aimed at helping frail older adults after they get discharged from the hospital. The AdvantAGE study aims to explore the following questions:

  • Does the new care model help reduce the number of patients who need to return to the hospital within 90 days?
  • How effective is the implementation of this care model?

Participants in the trial will be followed by advanced practice nurses for up to 90 days after hospital discharge. The patients and their caregivers will receive support in coordinating care, managing medications, and learning to manage the patient's health conditions on their own. Additionally, they will have the opportunity to engage in discussions about advanced care planning.

02

Conditions studied

  • Transitional Care
  • Multimorbidity
  • Geriatric Care

Keywords

  • Transitional Care, Frailty, Rehospitalisation, Geratric Care
03

In context

Lead sponsor

This is the only study on the registry with Thekla Brunkert as lead sponsor.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
65 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Currently admitted to the acute or rehabilitation ward of University Department of Geriatric Medicine
  • Reside in Basel-Stadt
  • Possess the ability to speak and comprehend the German language
  • Scheduled to be discharged to their home
  • 65 years or older
  • Identified by a clinician as having a high risk of deterioration due to frailty

Additionally, participants must meet at least one of the following criteria:

  • diagnosed with a complex chronic disease requiring support in self-management and disease management, or
  • facing socially challenging situations such as living alone without a supportive network or lacking a GP, or
  • admitted for an acute illness with a brief hospital stay (e.g., infection, cardiac decompensation) and need support in self- and disease management, and continuity of the therapy plan, including close monitoring.

Exclusion criteria

Exclusion Criteria:

  • residing in a nursing home or being newly admitted to one
  • lacking informal caregivers and exhibiting severe cognitive impairment (MMS ≤23)
  • scoring \<50 on the motoric domain of the Functional Independence Measure (FIM)
  • having a psychiatric disorder that significantly impacts their ability to manage daily life at time of the discharge
05

Study design

Phase
Not applicable
Primary purpose
Health services research
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
250 participants (estimated)

Study arms

  • Experimental
    Intervention group

    The intervention includes five core elements provided by a multiprofessional team: (1) continuous support for patients and caregivers; (2) care coordination with primary care providers;(3) visits at patients' homes; (4) medication- and self-management with patients and caregivers; and (5) proactive advanced care planning. Patients will receive specialized support including home visits up to 90 days after hospital discharge.

    Other: Transitional care model

Interventions

  • OtherTransitional care model

    A newly developed care model to support frail older adults during their transition from hospital to home.

    Also known as: AdvantAGE

06

What researchers measure

Primary outcomes

  1. 90-days rehospitalization rate

    Number of unplanned hospital admissions of any kind happening within 90 days after discharge

    Time frame: 90 days post-discharge

Secondary outcomes

  1. 30-days rehospitalization rate

    Number of unplanned hospital admission of any kind happening within 30 days after discharge

    Time frame: 30 days post-discharge

  2. Time to readmission

    Number of days between hospital discharge and unplanned hospital admission

    Time frame: Up to 90 days post-discharge

  3. Number of emergency room visits

    Number of emergency room visits (with or without hospital admission) within 90 days after discharge

    Time frame: 90 days post-discharge

  4. Time to emergency room visit

    Number of days between hospital discharge and emergency room visit

    Time frame: Up to 90 days post-discharge

  5. Patient's health-related quality of life

    The EuroQoL-5D-5L is used to assess the health-related quality of life in patients at three time points. Prior to hospital discharge, 7 days and 90 days after hospital discharge or if the patient completed the intervention

    Time frame: Up to 90 days post-discharge

  6. Patient satisfaction questionnaire

    Satisfaction regarding intervention participation

    Time frame: up to 90 days post-discharge

07

Study locations

1 of 1 sites recruiting
  • Universitäre Altersmedizin FELIX PLATTER
    Basel, 4055, Switzerland
    Recruiting
08

References and documents

Individual participant data

Plan to share: No

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Feb 2, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT06190288
Lead sponsor
Thekla Brunkert
Collaborators
Health Department of the Canton of Basel-Stadt
Responsible party
Thekla Brunkert (Principle Investigator, University Department of Geriatric Medicine FELIX PLATTER) — Sponsor-investigator
First posted
Jan 5, 2024
Start date
Jan 8, 2024
Primary completion
Jun 30, 2026 (estimated)
Completion
Jun 30, 2026 (estimated)
Last update
Feb 2, 2024

Study contacts

Mario Ernst
Contact
mario.ernst@felixplatter.ch
+41 61 326 44 81
Isabel Pfundstein
Contact
isabel.pfundstein@felixplatter.ch
+41 61 326 44 81
Thekla Brunkert, PhD
principal investigator · Universitäre Altersmedizin FELIX PLATTER

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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