CClinicalTrials.gg
Not yet recruitingNCT06174935Updated Dec 18, 2023

Low Dose Atropine for Symptomatic Vitreous Floaters

A Phase 2 interventional study of 0.01% atropine ophthalmic drop in Vitreous Floaters, sponsored by Jeanette Du. Not yet recruiting at 1 site in United States. Open to participants aged 19 Years and older. Per ClinicalTrials.gov, last updated 2023-12-18.

Sponsored by Jeanette Du · Phase 2, Interventional, and Treatment

From the registry’s dates

  • Primary completion was expected by Jun 2024, 2 years 4 months ago, but the record still lists the study as not yet recruiting.
Phase
Phase 2
Study type
Interventional
Enrollment
200
Allocation
Not applicable
Ages
19 Years and older
Sex
All
01

Study summary

The objective of this study is to identify a potential pharmacologic option by assessing whether 0.01% atropine may be effective for treating bothersome floaters as measured by scores on a modified NEI VFQ-25.

02

Conditions studied

  • Vitreous Floaters

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03

In context

Eye Diseases

740 studies on the registry are indexed under Eye Diseases; 117 are open to participants now.

This study's planned enrollment of 200 is above the median of 68 across 547 interventional studies indexed under Eye Diseases.

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Lead sponsor

This is the only study on the registry with Jeanette Du as lead sponsor.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
19 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Adult patients within Prism Vision Group with ICD diagnosis of acute posterior vitreous detachment and none of the ocular comorbidities listed as exclusion criteria will be screened as potential study participants.

Exclusion criteria

Exclusion Criteria:

  • Patients with vitreous hemorrhage, other significant media opacity or vitreoretinal pathology, or history of pars plana vitrectomy will be excluded.
05

Study design

Phase
Phase 2
Primary purpose
Treatment
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
200 participants (estimated)

Study arms

  • Experimental
    Atropine 0.01%

    Patients will apply 1 drop daily of atropine 0.01%

    Drug: 0.01% atropine ophthalmic drop

Interventions

  • Drug0.01% atropine ophthalmic drop

    0.01% atropine ophthalmic drop will be applied daily to the affected eye

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What researchers measure

Primary outcomes

  1. Symptom improvement assessed by questionnaire

    NEI VFQ-25 = National Eye Institute Visual Function Questionnaire

    Time frame: Up to 2 months

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Study locations

1 site
  • Retina Group of Washington
    Reston, Virginia 20190, United States
    • Jeanette Du, MD · Contact · jdu@rgw.com · 844-749-3627
    • Jeanette Du, MD · Sub investigator
    • Mohsin Ali, MD · Principal investigator
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Dec 18, 2023, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT06174935
Lead sponsor
Jeanette Du
Responsible party
Jeanette Du (Physician, Prism Vision Group) — Sponsor-investigator
First posted
Dec 18, 2023
Start date
Jan 1, 2024 (estimated)
Primary completion
Jun 1, 2024 (estimated)
Completion
Jun 1, 2024 (estimated)
Last update
Dec 18, 2023

Study contacts

Jeanette Du, MD
Contact
JDu@rgw.com
844-749-3627

Oversight

FDA-regulated drug
Yes
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Dec 2023. You cannot join it, but the record below documents what was studied.

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