A Phase 4 interventional study of Domperidon and Placebo in Emotions, sponsored by German Institute of Human Nutrition. Status unknown at 1 site in Germany. Open to participants aged 18 Years to 40 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2023-12-14.
Sponsored by German Institute of Human Nutrition · Phase 4, Interventional, and Basic science
The study will examine the influence of domperidon (20mg) on brain and hebavioral responses to emotional stimuli (videos) using fMRI
German Institute of Human Nutrition is the lead sponsor of 34 studies on the registry; 9 are open to participants now.
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Exclusion criteria
Participants recieve 10mg of Domperidon, 45 minutes before the start of the experiment
Drug: Domperidon
Participants recieve a placebo pill, 45 minutes before the start of the experiment
Drug: Placebo
oral
oral tablet
Brain responses to emotions
fMRI brain responses to emotional videos comparing placebo vs domperidon condition. Specifically: dampened brain response to disgust and high arousing videos in domperidon condition
Time frame: 1-3 hour after drug administratrion
Body (stomach, heart, skin conductance) response to emotions
Physiological responses to emotional videos comparing placebo vs domperidon condition. Specifically: Reduction in Tachyhastria for disgust and high arousing videos in domperidone condition
Time frame: 1-3 hour after drug administratrion
Behavioral responses to emotions
Changes in subjective reports to emotional videos comparing placebo vs domperidon condition. Specifically: Reduction in disgust and arousal ratings to disgust and high arousing videos
Time frame: 1-3 hour after drug administratrion
Plan to share: Undecided
No publications or documents are linked to this record.
Started Aug 2023 (actual). Primary completion is estimated for Mar 2024, 7 months after the start.
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This study is status unknown, as verified in Dec 2023. You cannot join it, but the record below documents what was studied.
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Studies of the drug tested here: Domperidone
German Institute of Human Nutrition