An observational study in COVID-19, SARS CoV 2 Infection and COVID-19 Pandemic, sponsored by Institut de Recherche pour le Developpement. Completed at 1 site in Benin. Per ClinicalTrials.gov, last updated 2023-12-21.
Sponsored by Institut de Recherche pour le Developpement · Observational
The aim of this observational study was to develop, with the intended users, an epidemic surveillance and response system that will be effective, sensitive, coordinated and appropriate.
The STREESCO project aims to
Within the framework of the health systems set up by the Benin health authorities, the project aims to develop, with the intended users, an epidemic surveillance and response system that will be effective, sensitive, coordinated and adapted to a context where resources are limited. Following the start of data collection on 01 March 2021, new reforms to the response strategy against CoVID-19 in Benin have led the investigators to opt for a new strategy in order to meet the objectives of the study. The epidemiological surveillance system will be adapted to the reforms, and data collected and processed prospectively on the dynamics of the epidemic will be collected in CoVID-19 screening centres and in public and private health centres. This is the scientific data needed to issue an early warning signal and enable the healthcare system to respond appropriately. The information system will be based on (i) epidemiological surveys in the field, (ii) virological, serological and antigenic tests, (iii) indicators that will enable action to be monitored, adaptation to the epidemic to be assessed and the response capacity of health structures to be controlled. Analysis (biostatistics, geo-epidemiology) of the data collected will provide useful knowledge for a better understanding of the dynamics of the epidemic. Finally, the project will encourage collaboration between African and European researchers and strengthen the capacity of African institutions to set up an epidemic surveillance system.
7,990 studies on the registry are indexed under COVID-19; 466 are open to participants now.
This study's enrollment of 7,000 is above the median of 268 across 3,208 observational studies indexed under COVID-19.
Browse COVID-19 studies →Institut de Recherche pour le Developpement is the lead sponsor of 49 studies on the registry; 4 are open to participants now.
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This surveillance was carried out in 03 strategic sites: in Cotonou, the economic capital, in Allada, a town on the border of the cordon sanitaire set up in March 2020, and in Natitingou, a town in northern Benin outside the cordon sanitaire. It was based in the health units involved in the response to COVID-19 at the 03 strategic sites. Initially, we included volunteers for COVID-19 screening, contact cases of positive subjects, and health workers present in the centres. Secondly, The study population consisted of pregnant women in the third trimester (≥ 28 weeks) of pregnancy seen for antenatal care (ANC) in the study maternity units of the 03 strategic sites were surveyed in order to describe their serological status with respect to SARS-CoV-2 infection.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Proportion of subjects infected with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) by strategic sites (suspected cases, contact cases)
Total number of subjects with a positive COVID-19 test divided by the total number of volunteers tested in the study.
Time frame: 9 months
Average number of contact cases per person infected with SARS-CoV-2 across all the study sites was as follows
Identify the number of contact cases per subject testing positive for SARS-CoV-2 infection at each of the strategic sites.
Time frame: 9 months
Factors associated with SARS-CoV-2 infection in volunteers screened at 03 strategic sites
Multivariate logistic regression model on sociodemographic, anthropometric, clinical and environmental characteristics of volunteer subjects screened for SARS-CoV-2 infection
Time frame: 9 months
Clusters of cases in the area of each strategic site (radius, period, relative risk)
Analysis of the spatial distribution of positive cases of SARS-CoV-2 infection on each of the strategic sites
Time frame: 9 months
Intra-district incidence rate on the 03 strategic sites
Number of positive cases for SARS-CoV-2 infection divided by the total number of the population multiplied by 1000.
Time frame: 9 months
Environmental factors associated with incidence rates and hotspots
Binomial mixed generalized additive model (GAMM)
Time frame: 9 months
Basic reproduction number for each strategic site and overall
Bayesian approach to quantify transmissibility over time during the epidemic at each site and overall.
Time frame: 9 months
Proportion of health workers infected with SARS-CoV-2 by strategic sites
Total number of health workers with a positive COVID-19 test divided by the total number of health workers tested in the study.
Time frame: 9 months
Factors associated with SARS-CoV-2 infection in health workers at 03 strategic sites
Multivariate logistic regression model on sociodemographic, anthropometric, clinical and environmental characteristics, prevention and control measures among health workers for SARS-CoV-2 infection.
Time frame: 9 months
Seroprevalence of SARS-CoV-2 infection among pregnant women in the 3rd trimester in maternity wards of strategic study sites
Number of pregnant women with a positive Rapid Diagnostic Test (RDT) divided by the total number of pregnant women tested during the study.
Time frame: 3 months
Factors associated with SARS-CoV-2 sero-infection in pregnant women in the 3rd trimester at 03 strategic sites
Multivariate logistic regression model on sociodemographic, anthropometric, clinical, linked to the course of pregnancy and vaccination status characteristics in pregnant women in the 3rd trimester at 03 strategic sites
Time frame: 3 months
Plan to share: No
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This study is completed, as verified in Dec 2023. You cannot join it, but the record below documents what was studied.
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Institut de Recherche pour le Developpement