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CompletedNCT06170034Updated Jan 30, 2025

Post-emergency Management of Patients with Transient Ischemic Attack

An observational study in Transient Ischemic Attack, sponsored by Centre Hospitalier Henri Duffaut - Avignon. Completed at 1 site in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-01-30.

Sponsored by Centre Hospitalier Henri Duffaut - Avignon · Observational

Study type
Observational
Model
Other
Time perspective
Prospective
Enrollment
49
Ages
18 Years and older
Sex
All
01

Study summary

A transient ischemic attack (TIA) is a momentary neurological dysfunction due to a brief cessation of blood flow to a region of the brain, resulting in typical signs of stroke (hemiplegia, aphasia, dysarthria), but whose clinical symptoms typically last less than an hour, with no visible lesion on imaging. This diagnosis remains difficult and is essentially based on the clinical judgment of the physician.

Because a TIA can be a "pre-alarm" for stroke in 20-30% of cases, it needs to be treated appropriately and as early as possible in the emergency department. Stroke rates after untreated TIA are 5% within 48 hours, 10% within one month and 20% within one year. This risk is calculated using the ABCD² score which is based on the patient's risk factors and the clinical manifestations of TIA. Patients with a score ≥ 3 should be hospitalized as soon as possible for a complete medical evaluation. However, this score has not been scientifically validated, and several specialists agree that all TIAs should be evaluated immediately. Preventing stroke is a major public health issue because it is a serious, disabling and sometimes fatal disease. Given the seriousness of the progression from TIA to stroke, the French National Authority for Health has issued a series of management recommendations. However, in practice, these guidelines remain complicated to follow and patients management may vary and be more or less effective.

Therefore, the aim of this study is to highlight the differences in how inpatients and outpatients are managed. Following these observations, solutions will be sought to make the care and management of these patients more efficient and more in line with recommendations.

02

Conditions studied

  • Transient Ischemic Attack

Keywords

  • Emergency
  • Cerebral RMI
  • Guidelines compliance
03

In context

Ischemic Attack, Transient

329 studies on the registry are indexed under Ischemic Attack, Transient; 71 are open to participants now.

This study's enrollment of 49 is below the median of 343 across 140 observational studies indexed under Ischemic Attack, Transient.

Browse Ischemic Attack, Transient studies →

Lead sponsor

Centre Hospitalier Henri Duffaut - Avignon is the lead sponsor of 10 studies on the registry; 5 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Patients with a diagnosis of TIA in the emergency department

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Patient over 18 years old.
  • Consultation in the emergency department.
  • Suspected diagnosed by emergency physician.
  • Duration of TIA symptoms \<1 hour.

Exclusion criteria

Exclusion Criteria:

  • Validation MRI performed prior to suspected .
  • Patient hospitalized for a condition other than TIA, including stroke.
  • Patient referred to another hospital for further examination.
  • Pregnant women.
  • Patient unable to understand and answer a questionnaire.
  • Patient under legal protection.
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

TIA (transient ischaemic attack)

A “mini-stroke”: temporary stroke-like symptoms caused by reduced blood flow to part of the brain, spinal cord or eye, without signs of a new stroke on a scan.

Stroke symptoms need emergency care at once, even if they go away.

05

Study design

Observational model
Other
Time perspective
Prospective
Enrollment
49 participants (actual)
Patient registry
No

Groups and cohorts

  • TIA patients

    Behavioral: Satisfaction questionnaire · Other: Medical care questionnaire

Interventions

  • BehavioralSatisfaction questionnaire

    Satisfaction questionnaire to assess how TIA patients feels about their medical care.

  • OtherMedical care questionnaire

    Recording appointments and results of examinations and consultations in TIA management

06

What researchers measure

Primary outcomes

  1. Assess time between arrival in the emergency department for suspected TIA patients and MRI.

    Time frame: Baseline

Secondary outcomes

  1. Time between arrival in the emergency department and MRI by departments.

    Time frame: Baseline

  2. Time between arrival in the emergency department and MRI by ABCD² score.

    Time frame: Baseline

  3. Percentage of patients with complete TIA management by departments.

    Time frame: Baseline

  4. Hospitalization times according to care units

    Time frame: Baseline

  5. Hospitalization times according to complete TIA management

    Time frame: Baseline

  6. Percentage of patients with secondary event, according to complete TIA management

    Time frame: Baseline

  7. Number of outpatients without complete TIA management one month after TIA.

    Time frame: At 1 month follow-up

  8. Patient satisfaction with a short questionnaire

    Time frame: At 1 month follow-up

07

Study locations

1 site
  • Centre Hospitalier d'Avignon
    Avignon, France
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 30, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT06170034
Lead sponsor
Centre Hospitalier Henri Duffaut - Avignon
Responsible party
Sponsor
First posted
Dec 14, 2023
Start date
Nov 16, 2023
Primary completion
May 16, 2024
Completion
Jun 16, 2024
Last update
Jan 30, 2025

Study contacts

Yohan Fouilhe, Medical Intern
principal investigator · Centre Hospitalier d'Avignon, Service des urgences

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Jan 2025. You cannot join it, but the record below documents what was studied.

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