ClinicalTrials.gg
Sign In
RecruitingNCT06163300Updated Jan 30, 2024

MRI Analysis and Degenerative Spine

An observational study in Spine Disease, sponsored by Universidade Nova de Lisboa. Recruiting at 1 site in Portugal. Open to participants aged 50 Years to 85 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2024-01-30.

Sponsored by Universidade Nova de Lisboa · Observational

From the registry’s dates

  • Primary completion was expected by Sep 2024, 2 years 2 months ago, but the record still lists the study as recruiting.
  • Started Jan 2024; still recruiting 2 years 10 months later.
Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
200
Ages
50 Years to 85 Years
Sex
All
01

Study summary

Analysis of MRI advanced techniques in degenerative spinal disease.

The main questions it aims to answer are:

  • Can we assess microstructural integrity of compressed nerve roots in degenerative spinal disease
  • What are the image biomarkers affected by disease
  • How they evolve with disease progression and treatment
02

Conditions studied

  • Spine Disease

Browse trials for

03

In context

Spinal Diseases

174 studies on the registry are indexed under Spinal Diseases; 39 are open to participants now.

This study's planned enrollment of 200 is above the median of 117 across 64 observational studies indexed under Spinal Diseases.

Browse Spinal Diseases studies →

Lead sponsor

Universidade Nova de Lisboa is the lead sponsor of 43 studies on the registry; 12 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
50 Years to 85 Years
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

Patients with suspected diagnosis of the spinal disease in study and that meet the eligibility criteria.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Age between 50 and 85 years
  • Diagnosis of spinal disease by clinical and imagiological criteria
  • More than 3 months duration of disease
  • Ability to give consent
  • Fluent portuguese speaker

Exclusion criteria

Exclusion Criteria:

  • Previous spine surgery
  • Spinal instability
  • Neurological disease that might interfere with walking
  • Known orthopedic conditions that causes significant gait impairment
  • Dementia or development disorder with cognitive impairment
  • Inability to give consent
05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
200 participants (estimated)
Patient registry
No

Groups and cohorts

  • Control

    Healthy volunteers

    Diagnostic Test: MRI advanced techniques

  • Disease

    Patients affected by disease

    Diagnostic Test: MRI advanced techniques

Interventions

  • Diagnostic testMRI advanced techniques

    Participants will be submitted to MRI studies at diagnosis, during disease evolution and after treatment. Data collected will be analysed by two different neuroradiologists using advanced techniques.

06

What researchers measure

Primary outcomes

  1. ODI - Oswestry Disability Index

    Measured using the ODI scale (range 0 - 50)

    Time frame: 18 months

  2. Lumbar Pain Intensity

    Measured using the Numeric Pain Rating Scale (range: 0 - 10 )

    Time frame: 18 months

07

Study locations

1 of 1 sites recruiting
08

References and documents

Individual participant data

Plan to share: Undecided

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 30, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT06163300
Lead sponsor
Universidade Nova de Lisboa
Responsible party
Sponsor
First posted
Dec 8, 2023
Start date
Jan 1, 2024
Primary completion
Sep 2024 (estimated)
Completion
Sep 2026 (estimated)
Last update
Jan 30, 2024

Study contacts

Nuno A.R. Cristino, M.D.
Contact
nuno.cristino.ext@nms.unl.pt
+351919484946

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Interested in this study?

Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.

Contact study team

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Other studies in this condition

Spinal Diseases →

Other studies from this sponsor

Universidade Nova de Lisboa

Start the discussion