An interventional study of Avocado Group in Brain Aging, sponsored by University of Kansas Medical Center. Recruiting at 1 site in United States. Open to participants aged 65 Years to 85 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2024-08-22.
Sponsored by University of Kansas Medical Center · Not applicable, Interventional, and Prevention
The goal of this clinical trial is to determine if adding avocados to the diet of impacts cognition in 70 older adults, age 65-85, without dementia. We will test for change in functional MRI, cognitive performance, and brain blood flow. Intervention group participants will be asked to consume 1 avocado per day for 12 weeks. Participants in the control group will be asked to continue their normal intake for 12 weeks. Throughout the study, participants will be asked to perform cognitive tests, MRI, blood tests, and questionnaires.
University of Kansas Medical Center is the lead sponsor of 483 studies on the registry; 113 are open to participants now.
Of its 38 completed or terminated interventional studies of FDA-regulated products, 24 (63%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Participants will consume 1 avocado per day and receive education to maintain usual caloric intake for 12 weeks and participate in 4 study visits.
Other: Avocado Group
Participants will continue their normal dietary pattern for 12 weeks and participate in 4 study visits.
Participants will consume provided avocados daily and track consumption for the duration of the study. Participants will be adding avocados to their diet and will receive education on maintaining usual diet.
Change in brain activity
MRI will be used to measure changes in brain activity during resting state, a working memory task, and executive function task.
Time frame: Baseline and 12 weeks
Changes in cerebral blood flow
MRI will be used to measure change in cerebral blood flow.
Time frame: Baseline and 12 weeks
Changes in memory and executive function
NIH Toolbox will be used to measure change in cognition throughout the study.
Time frame: Baseline and 12 weeks
Plan to share: No
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University of Kansas Medical Center