An interventional study of Bilateral resistance exercise and Whey protein in Muscle Metabolism, sponsored by University of Exeter. Completed at 1 site in United Kingdom. Open to participants aged 18 Years to 40 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2023-11-13.
Sponsored by University of Exeter · Not applicable, Interventional, and Basic science
Dietary protein ingestion is required to maximise the anabolic response during the recovery from resistance exercise. Whey protein is considered the optimal dietary strategy to maximise post-exercise muscle protein synthesis, but animal-protein production and consumption is associated with growing environmental and ethical concerns. Plant-based protein sources are considered of lesser anabolic quality than isonitrogenous boluses of animal-derived protein attributed to, at least in part, deficiencies in key essential amino acid. Blending different protein sources may overcome amino acid deficiencies and potentiate the post-exercise anabolic response. In the present study the investigators assessed the post-exercise muscle protein synthetic response following the ingestion of a novel plant-based protein isolate when compared with an isonitrogenous bolus of whey protein in healthy young, resistance trained women and men.
University of Exeter is the lead sponsor of 138 studies on the registry; 25 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Following a bout of bilateral resistance exercise, participants will ingest 32 g protein from whey protein isolate
Behavioral: Bilateral resistance exercise · Dietary Supplement: Whey protein
Following a bout of bilateral resistance exercise, participants will ingest 32 g protein from a novel plant-blend protein isolate
Behavioral: Bilateral resistance exercise · Dietary Supplement: Plant-blend protein
A bout of bilateral resistance exercise consisting of barbell back squat, leg leg press and leg extension
Following execution of bilateral resistance exercise, participants will ingest 32 g protein from whey protein isolate
Following execution of bilateral resistance exercise, participants will ingest 32 g protein from plant-blend protein isolate
Post-exercise myofibrillar protein synthesis following protein ingestion
The fractional synthetic rate of myofibrillar proteins
Time frame: 4 hours
Post-exercise myofibrillar protein synthesis during the early postprandial period
The fractional synthetic rate of myofibrillar proteins
Time frame: 2 hours
Post-exercise myofibrillar protein synthesis during the late postprandial period
The fractional synthetic rate of myofibrillar proteins
Time frame: 2 hours
Plasma amino acid response
Post-exercise and postprandial change in plasma amino acid concentrations and availability
Time frame: 4 hours
Serum insulin response
Post-exercise and postprandial change in serum insulin concentrations
Time frame: 4 hours
This study is completed, as verified in Nov 2023. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
University of Exeter