An observational study in Ss-octa, Lid Margin Blood Flow Density and MGD, sponsored by Wenzhou Medical University. Not yet recruiting. Open to participants aged 20 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2023-10-19.
Sponsored by Wenzhou Medical University · Observational
To explore an optimized scan technique for the detection of lid margin vasculature
To investigate whether the SS-OCTA tool has the potential to characterize the lid margin vascularity in MGD patients. The repeatability and validity of OCTA in assessing eyelid margin blood flow density was evaluated。
Wenzhou Medical University is the lead sponsor of 94 studies on the registry; 8 are open to participants now.
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MGD or normal patients who could cooperate with dry eye evaluation and SSOCTA examination in the dry eye Clinic of the Eye Hospital of Wenzhou Medical University were enrolled.
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The MGD patients were aged >_20 years and were diagnosed according to Chinese MGD diagnostic criteria,11 including dry eye symptoms, and at least one of the following signs: (1) poor meibum expressibility or quality; (2) at least one of eyelid margin abnormalities (lid margin irregularity, plugging of the gland orifice, vascular engorgement/telangiectasia, and anterior replacement of the mucocutaneous junction. Normal subjects were defined as adults without any dry eye symptoms and lid margin abnormality.
Exclusion Criteria:
(1) subjects with ocular diseases or conditions known to affect the anatomy of the anterior segment, such as acute ocular inflammation, a history of eyelid surgery, contact lens wear within two weeks, and/or eyelid trauma; (2) subjects with of history of systemic or topical medications that might cause ocular congestion; (3) subjects with severe systemic illness or pregnancy; and (4) subjects who were difficult to cooperate with examination, resulting the obtained images were not sufficiently clear for automatic analysis.
Mild group, the scores of both clinicians were ≤ grade 1
Moderate group, one doctor scored grade 2, and the other doctor scored 1\~2;
Moderate group, one doctor scored grade 2, and the other doctor scored 1\~2;
LMBFD
Lid margin blood flow density
Time frame: Immediately after ssocta
No study locations are listed for this record.
Plan to share: No
No publications or documents are linked to this record.
This study is not yet recruiting, as verified in Oct 2023. You cannot join it, but the record below documents what was studied.
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Wenzhou Medical University