An interventional study of Physical Exercise Intervention in Physical Inactivity, sponsored by University of Basel. Completed at 1 site in Switzerland. Open to participants aged 60 Years to 80 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-06-25.
Sponsored by University of Basel · Not applicable, Interventional, and Prevention
Physical exercise is well known to improve human health. Current guidelines provide recommendations on the frequency, intensity, type and duration of exercise. However, they do not provide recommendations for the time of day, exercise should be performed. This is surprising considering that the influence of timing of behaviors such as sleep or nutrition as well as the impact of the circadian timing system on health are well documented. Further, there is evidence for diurnal variation in maximum performance which enables individuals to exercise with different intensities at different times of day, which in the long term might affect physical adaptations to exercise. Thus, this research study investigates if exercise timing impacts human health.
332 studies on the registry are indexed under Sedentary Behavior; 155 are open to participants now.
This study's enrollment of 152 is above the median of 70 across 287 interventional studies indexed under Sedentary Behavior.
Browse Sedentary Behavior studies →University of Basel is the lead sponsor of 61 studies on the registry; 9 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Single life-style coaching session
Physical exercise intervention taking place at one time of the day
Other: Physical Exercise Intervention
Physical exercise intervention taking place at another time of day
Other: Physical Exercise Intervention
Two strength training session per week and one endurance training session per week
Maximum strength
Mean value of the maximum isometric strength assessed at four different times of the day with an isometric mid-thigh pull on a force plate.
Time frame: Pre-Intervention (i.e. 1 to 28 days before the first training session of the exercise intervention) and Post-Intervention (i.e. 1 to 28 days after the last training session of the exercise intervention)
Glucose control
2-h postprandial area under the curve for glucose after an oral glucose tolerance test
Time frame: Pre-Intervention (i.e. 1 to 28 days before the first training session of the exercise intervention) and Post-Intervention (i.e. 1 to 28 days after the last training session of the exercise intervention)
Body composition
total body fat mass assessed with DXA
Time frame: Pre-Intervention (i.e. 1 to 28 days before the first training session of the exercise intervention) and Post-Intervention (i.e. 1 to 28 days after the last training session of the exercise intervention)
Cardiorespiratory fitness
VO2max assessed with cardiopulmonary exercise test
Time frame: Pre-Intervention (i.e. 1 to 28 days before the first training session of the exercise intervention) and Post-Intervention (i.e. 1 to 28 days after the last training session of the exercise intervention)
Plan to share: Yes — Anonymized data will be provided in a data repository in accordance to FAIR principles
No publications or documents are linked to this record.
This study is completed, as verified in Jun 2025. You cannot join it, but the record below documents what was studied.
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University of Basel