An observational study in Endometrial Cancer, sponsored by Latin American Cooperative Oncology Group. Completed at 10 sites in Brazil. Open to female participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-08-27.
Sponsored by Latin American Cooperative Oncology Group · Observational
An evaluation of the molecular and epidemiological aspects of endometrial cancer in Brazil is necessary to understand the high frequency of advanced disease. A better understanding of the current situation will generate essential data for the future development of national or international cooperative programs that aim to improve outcomes in these patients and generate additional knowledge for much-needed clinical trials in this population.
This is a retrospective observational cohort study. In this study, we will include patients diagnosed with endometrium cancer from January 2016 to December 2019 in participating sites and collect data on demographics, clinicopathological characteristics, treatment patterns, and outcomes. Data will be collected from medical records in selected centers that comprise different regions of Brazil.
The patient data sources will be the medical records of the patients. Patients will continue to receive treatment and clinical evaluations for endometrial cancer according to what is determined by their medical team, according to the usual standards of treatment and clinical practice of each center. To minimize patient selection bias, physicians should invite all consecutive eligible patients.
This study also provides for the collection and archiving of tumor tissue material. The samples will be tested to characterize the molecular subtype of endometrial cancer and will be sequentially stored in a biorepository to enable future translational studies, according to national regulations.
1,325 studies on the registry are indexed under Endometrial Neoplasms; 447 are open to participants now.
This study's enrollment of 276 is above the median of 179 across 321 observational studies indexed under Endometrial Neoplasms.
Browse Endometrial Neoplasms studies →Latin American Cooperative Oncology Group is the lead sponsor of 46 studies on the registry; 9 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Women diagnosed with endometrial cancer between January 2016 and December 2019 at participating research sites.
Exclusion Criteria:
Patients diagnosed with endometrial cancer between January 2016 and December 2019 at participating sites will be included.
Other: Observational study
This is an observational study; patients will not be exposed to clinical interventions different from those belonging to the standard of care.
Epidemiological Characteristics of the Brazilian Population with Endometrial Cancer
This measure encompasses key epidemiological factors of the Brazilian population diagnosed with endometrial cancer, including age distribution, racial and ethnic demographics, geographic regions, and relevant comorbidities. These details will provide insights into the demographic makeup of the study population.
Time frame: At the time of diagnosis.
Molecular Profile Analysis of Endometrial Cancer Cases
This measure focuses on analyzing the molecular profile of endometrial cancer cases in the Brazilian population. It includes information about specific genetic mutations, biomarkers, and molecular subtypes that are relevant to endometrial cancer. Understanding the molecular landscape can contribute to insights into disease progression and potential targeted therapies.
Time frame: Throughout the study period, an average of 36 month.
Treatment Patterns for Endometrial Cancer in Brazil
This measure examines the treatment patterns employed for endometrial cancer within the Brazilian population. It includes details about types of treatments received, such as surgery, chemotherapy, radiation therapy, and hormonal therapy. Additionally, it explores the utilization of targeted therapies or immunotherapies.
Time frame: From diagnosis to completion of treatment, between January 2016 and December 2019.
Endometrial Cancer Outcomes in the Brazilian Population
This measure assesses the outcomes of endometrial cancer cases in the Brazilian population. It includes survival rates, disease recurrence rates, response to treatment, and overall disease progression. By evaluating these outcomes, a comprehensive understanding of the disease's impact on the population can be achieved.
Time frame: From diagnosis to the end of the study follow-up period, an average of 36 months.
Plan to share: Undecided
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This study is completed, as verified in Aug 2026. You cannot join it, but the record below documents what was studied.
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Latin American Cooperative Oncology Group