CClinicalTrials.gg
CompletedNCT06011161BRCUpdated Oct 1, 2024Results posted

A Pilot of the Brief Relationship Checkup

An interventional study of Brief Relationship Checkup (BRC) in Relationship Distress, sponsored by Canandaigua VA Medical Center. Completed at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2024-10-01.

Sponsored by Canandaigua VA Medical Center · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
40
Allocation
Not applicable
Ages
18 Years and older
Sex
All
01

Study summary

The goal of this pilot trial is to study the Brief Relationship Checkup (BRC) program for Veterans with a combination of mental health and relationship concerns.

BRC has been studied in Air Force primary care, but has never been tested in the Department of Veterans Affairs. To prepare for a larger study of BRC, the investigators asked the following questions:

  1. Can the research team deliver BRC to Veterans with mental health concerns? ("Feasibility")
  2. What is the best way to measure BRC's impact? ("Pilot Outcomes")
  3. Does BRC fit the needs of Veterans, and if not, what changes would fit participants' needs? ("Refinement")

Participants completed an initial interview, attended the BRC program, and completed a follow-up interview.

Read the detailed description

PURPOSE: Relationship distress is a common problem for Veterans with mental health concerns. Relationship treatments like couple therapy are effective, but studies in the Department of Veterans Affairs (VA) find that they are infrequently used and have high dropout rates. One possible solution is for VA to offer Relationship Checkups, a short program that helps couples commit to concrete steps to improve their relationship. A brief version of the program designed for Air Force primary care -- called the Brief Relationship Checkup (BRC) for the purpose of the study -- may be an especially good fit for VA primary care or outpatient mental health teams.

RESEARCH PLAN: This study is a single-arm pilot trial of BRC in 20 couples. that are in distressed committed relationship where at least one partner is a Veteran who screens positive on a primary care mental health screen for common suicide risk factors including suicide ideation, depression, PTSD, or alcohol misuse (the "Identified Patient"). Participants provided initial ratings of outcomes in separate baseline sessions, completed BRC, and then completed separate post-treatment interviews and questionnaires.

SPECIFIC AIMS:

AIM 1: Evaluate feasibility of conducting a BRC trial in Veterans with mental health concerns. This includes recruitment rate, completion rate, and provider adherence to protocol.

AIM 2: Pilot outcomes that can be used to evaluate pre-post change in future studies of BRC. This includes relationship functioning, suicide risk factors, and treatment utilization.

AIM 3: Inform continued refinement of BRC to be suitable to the needs of Veterans and their partners. This includes examining current acceptability and using open-ended interviews.

02

Conditions studied

  • Relationship Distress

Keywords

  • Couple therapy
  • Primary Care
03

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  1. BOTH PARTNERS must be age 18 or over
  2. BOTH PARTNERS must demonstrate sufficient knowledge of English and cognitive capacity to understand the study through comprehension of consent questions
  3. BOTH PARTNERS must self-identify as "in a committed relationship" with their partner for at least 6-months.
  4. AT LEAST ONE PARTNER must report at least mild relationship distress on a satisfaction screen.
  5. AT LEAST ONE PARTNER must have Veteran status
  6. THE VETERAN PARTNER must screen positive on at least on a VA Primary Care Mental Health Screen (i.e., Patient Health Questionnaire(PHQ)-2 for Depression, PHQ Item 9 for Suicide Risk; Alcohol Use Disorders Identification Test Consumption Questions for At-Risk Drinking; or Primary Care-PTSD-5 for Potential PTSD)

Exclusion criteria

Exclusion Criteria:

  1. EITHER PARTNER reports that they are engaged in ongoing couple or family therapy.
  2. EITHER PARTNER reports severe intimate partner violence in the last year.
  3. EITHER PARTNER reports experiencing suicidal intent or suicidal attempts in the last month.
  4. EITHER PARTNER experiences current psychosis.
  5. EITHER PARTNER experiences current mania.
04

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
40 participants (actual)

Study arms

  • Experimental
    Brief Relationship Checkup

    Couples in the experimental condition will participate in three joint sessions of the Brief Relationship Checkup (BRC; Cordova 2014; Cigrang et al., 2016). This program has been tested in Air Force Primary Care but we do not know if veterans with mental health concerns will be able to attend it (feasibility), complete it safely (tolerability), and enjoy it (acceptability).

    Behavioral: Brief Relationship Checkup (BRC)

Interventions

  • BehavioralBrief Relationship Checkup (BRC)

    The investigators are using the three 30-minute session protocol developed for Air Force Primary Care (Cigrang et al., 2016). Although it is simply referred to as the "Marriage Checkup" in that manuscript, the investigators use the name BRC to distinguish it from many other versions of Dr. James Cordova's Marriage Checkup (Cordova, 2014) adapted for different settings. Sessions in this version are briefer than other versions (30 mins vs. 60-90 mins) and this trial does not have any eligibility restrictions based on marital status.

    Also known as: Marriage Checkup, Relationship Checkup

05

What researchers measure

Primary outcomes

  1. Relationship Functioning

    Relationship Functioning will be measured using the Couples Satisfaction Index (CSI). The self-report scale has a minimum of 0 and a maximum of 161 with higher scores representing more satisfying relationships and scores \< 104.5 classified as "distressed." The CSI is widely used in couple therapy research and is used routinely in VA care to evaluate Veterans' progress in evidence-based couple therapies.

    Time frame: Pre-treatment

  2. Relationship Functioning

    Relationship Functioning will be measured using the Couples Satisfaction Index (CSI). The self-report scale has a minimum of 0 and a maximum of 161 with higher scores representing more satisfying relationships and scores \< 104.5 classified as "distressed." The CSI is widely used in couple therapy research and is used routinely in VA care to evaluate Veterans' progress in evidence-based couple therapies.

    Time frame: After Completing the BRC Program (1-3months after pre-treatment)

Secondary outcomes

  1. Emotional Intimacy/Mutual Responsiveness

    Emotional Intimacy will be measured using the Perceived Responsiveness \& Insensitivity Scale (PRI). The PRI is an optimized measure of "Perceived Partner Responsiveness," a model of emotional intimacy that is widely used in the field to understand whether partners see one another as understanding/validating. The PRI has a minimum of 0 and a maximum of 80, with higher scores indicating greater sense of validation/understanding from one's partner.

    Time frame: Pre-treatment

  2. Emotional Intimacy/Mutual Responsiveness

    Emotional Intimacy will be measured using the Perceived Responsiveness \& Insensitivity Scale (PRI). The PRI is an optimized measure of "Perceived Partner Responsiveness," a model of emotional intimacy that is widely used in the field to understand whether partners see one another as understanding/validating. The PRI has a minimum of 0 and a maximum of 80, with higher scores indicating greater sense of validation/understanding (i.e., greater emotional intimacy).

    Time frame: After Completing the BRC Program (1-3months after pre-treatment)

  3. Depressive Symptoms

    Depression will be measured using the 9-item Patient Health Questionnaire (PHQ-9). This self-report scale has a minimum of 0 and a maximum of 27 with higher scores representing greater number and frequency of depression symptoms and scores of 10 or higher representing moderate depression.

    Time frame: Pre-treatment

  4. Depressive Symptoms

    Depression will be measured using the 9-item Patient Health Questionnaire (PHQ-9). This self-report scale has a minimum of 0 and a maximum of 27 with higher scores representing greater number and frequency of depression symptoms and scores of 10 or higher representing moderate depression.

    Time frame: After Completing the BRC Program (1-3months after pre-treatment)

  5. Perceived Burdensomeness

    Perceived burdensomeness will be measured with the burden-specific subscale of the Interpersonal Needs Questionnaire (INQ). This self-report scale has a minimum of 6 and a maximum of 42 with higher scores representing a stronger belief that one is a burden on others. Scores of 12 or higher predict a higher risk for developing suicidal ideation.

    Time frame: Pre-treatment

  6. Perceived Burdensomeness

    Perceived burdensomeness will be measured with the burden-specific subscale of the Interpersonal Needs Questionnaire (INQ). This self-report scale has a minimum of 6 and a maximum of 42 with higher scores representing a stronger belief that one is a burden on others. Scores of 12 or higher predict a higher risk for developing suicidal ideation.

    Time frame: After Completing the BRC Program (1-3months after pre-treatment)

  7. Thwarted Belongingness

    Thwarted belongingness will be measured with the belonging-specific subscale of the Interpersonal Needs Questionnaire (INQ). This self-report scale has a minimum of 9 and a maximum of 63 with higher scores representing a stronger feeling of loneliness and isolation. Scores of 36 or higher predict a higher risk for developing suicidal ideation.

    Time frame: Pre-treatment

  8. Thwarted Belongingness

    Thwarted belongingness will be measured with the belonging-specific subscale of the Interpersonal Needs Questionnaire (INQ). This self-report scale has a minimum of 9 and a maximum of 63 with higher scores representing a stronger feeling of loneliness and isolation. Scores of 36 or higher predict a higher risk for developing suicidal ideation.

    Time frame: After Completing the BRC Program (1-3months after pre-treatment)

  9. Suicide Ideation Severity

    Suicide ideation over the study will be monitored using the "Last Month" version of the Columbia Suicide Severity Rating Scale (CSSRS). This semi-structured interview has interviewers rate suicide ideation on a scale of 0 to 5, with scores of 3-5 placing individuals at high risk for attempt. VA hospitals use the C-SSRS across all clinics.

    Time frame: Pre-treatment

  10. Suicide Ideation Severity

    Suicide ideation over the study will be monitored using the "Last Month" version of the Columbia Suicide Severity Rating Scale (CSSRS). This semi-structured interview has interviewers rate suicide ideation on a scale of 0 to 5, with scores of 3-5 placing individuals at high risk for attempt. VA hospitals use the C-SSRS across all clinics.

    Time frame: After Completing the BRC Program (1-3months after pre-treatment)

  11. Treatment Acceptability

    Treatment acceptability was assessed using the Client Satisfaction Questionnaire (CSQ, Larsen et al., 1979). Scores range from 1-4 with scores greater than 3 representing satisfaction with the treatment.

    Time frame: After Completing the BRC Program (1-3months after pre-treatment)

Other outcomes

  1. Number of Mental Health and Family Contacts

    Treatment engagement in mental health services will be assessed through a review of the electronic medical record. Staff will review appointments (e.g., individual, group, assessments) with a specific focus on general mental health services and couple/family support services (including Caregiver Support program and Intimate Partner Violence Assistance Program).

    Time frame: 90 day period before pre-treatment session

  2. Number of Mental Health and Family Contacts

    Treatment engagement in mental health services will be assessed through a review of the electronic medical record. Staff will review appointments (e.g., individual, group, assessments) with a specific focus on general mental health services and couple/family support services (including Caregiver Support program and Intimate Partner Violence Assistance Program).

    Time frame: 90 day period after final treatment session (earliest window 1-4mo after pre-treatment session and latest window 3-6mo)

06

Results

Posted Oct 1, 2024
Limitations and caveats
This study is a small pilot without a comparison group and half of the Screened Veterans were participating in individual therapy. Therefore, it is possible that some of these couples may have been expected to naturally improve over time, and it is unclear how much of the improvements seen in this ClinicalTrials.gov registration are due to the treatment itself.

Participant flow

Participant flow — Overall Study
MilestoneBrief Relationship Checkup
Started40
Completed33
Not completed7
Withdrew: Withdrawal by subject2
Withdrew: Lost to follow-up5

Outcome measures

PrimaryRelationship Functioning

Relationship Functioning will be measured using the Couples Satisfaction Index (CSI). The self-report scale has a minimum of 0 and a maximum of 161 with higher scores representing more satisfying relationships and scores \< 104.5 classified as "distressed." The CSI is widely used in couple therapy research and is used routinely in VA care to evaluate Veterans' progress in evidence-based couple therapies.

Time frame:
Pre-treatment
Reported as:
Least squares mean · score on a scale
Relationship Functioning
score on a scaleScreened VeteranSecond Partner
Relationship Functioning84.99 ± 6.6090.90 ± 6.60
PrimaryRelationship Functioning

Relationship Functioning will be measured using the Couples Satisfaction Index (CSI). The self-report scale has a minimum of 0 and a maximum of 161 with higher scores representing more satisfying relationships and scores \< 104.5 classified as "distressed." The CSI is widely used in couple therapy research and is used routinely in VA care to evaluate Veterans' progress in evidence-based couple therapies.

Time frame:
After Completing the BRC Program (1-3months after pre-treatment)
Reported as:
Least squares mean · score on a scale
Relationship Functioning
score on a scaleScreened VeteranSecond Partner
Relationship Functioning117.66 ± 6.97106.81 ± 6.88
SecondaryEmotional Intimacy/Mutual Responsiveness

Emotional Intimacy will be measured using the Perceived Responsiveness \& Insensitivity Scale (PRI). The PRI is an optimized measure of "Perceived Partner Responsiveness," a model of emotional intimacy that is widely used in the field to understand whether partners see one another as understanding/validating. The PRI has a minimum of 0 and a maximum of 80, with higher scores indicating greater sense of validation/understanding from one's partner.

Time frame:
Pre-treatment
Reported as:
Least squares mean · score on a scale
Emotional Intimacy/Mutual Responsiveness
score on a scaleScreened VeteranSecond Partner
Emotional Intimacy/Mutual Responsiveness41.64 ± 4.4944.80 ± 4.49
SecondaryEmotional Intimacy/Mutual Responsiveness

Emotional Intimacy will be measured using the Perceived Responsiveness \& Insensitivity Scale (PRI). The PRI is an optimized measure of "Perceived Partner Responsiveness," a model of emotional intimacy that is widely used in the field to understand whether partners see one another as understanding/validating. The PRI has a minimum of 0 and a maximum of 80, with higher scores indicating greater sense of validation/understanding (i.e., greater emotional intimacy).

Time frame:
After Completing the BRC Program (1-3months after pre-treatment)
Reported as:
Least squares mean · score on a scale
Emotional Intimacy/Mutual Responsiveness
score on a scaleScreened VeteranSecond Partner
Emotional Intimacy/Mutual Responsiveness58.87 ± 4.6550.67 ± 4.61
SecondaryDepressive Symptoms

Depression will be measured using the 9-item Patient Health Questionnaire (PHQ-9). This self-report scale has a minimum of 0 and a maximum of 27 with higher scores representing greater number and frequency of depression symptoms and scores of 10 or higher representing moderate depression.

Time frame:
Pre-treatment
Reported as:
Least squares mean · score on a scale
Depressive Symptoms
score on a scaleScreened VeteranSecond Partner
Depressive Symptoms11.00 ± 0.987.50 ± 0.98
SecondaryDepressive Symptoms

Depression will be measured using the 9-item Patient Health Questionnaire (PHQ-9). This self-report scale has a minimum of 0 and a maximum of 27 with higher scores representing greater number and frequency of depression symptoms and scores of 10 or higher representing moderate depression.

Time frame:
After Completing the BRC Program (1-3months after pre-treatment)
Reported as:
Least squares mean · score on a scale
Depressive Symptoms
score on a scaleScreened VeteranSecond Partner
Depressive Symptoms8.17 ± 1.084.24 ± 1.06
SecondaryPerceived Burdensomeness

Perceived burdensomeness will be measured with the burden-specific subscale of the Interpersonal Needs Questionnaire (INQ). This self-report scale has a minimum of 6 and a maximum of 42 with higher scores representing a stronger belief that one is a burden on others. Scores of 12 or higher predict a higher risk for developing suicidal ideation.

Time frame:
Pre-treatment
Reported as:
Least squares mean · score on a scale
Perceived Burdensomeness
score on a scaleScreened VeteranSecond Partner
Perceived Burdensomeness11.14 ± 1.057.84 ± 1.07
SecondaryPerceived Burdensomeness

Perceived burdensomeness will be measured with the burden-specific subscale of the Interpersonal Needs Questionnaire (INQ). This self-report scale has a minimum of 6 and a maximum of 42 with higher scores representing a stronger belief that one is a burden on others. Scores of 12 or higher predict a higher risk for developing suicidal ideation.

Time frame:
After Completing the BRC Program (1-3months after pre-treatment)
Reported as:
Least squares mean · score on a scale
Perceived Burdensomeness
score on a scaleScreened VeteranSecond Partner
Perceived Burdensomeness9.76 ± 1.097.06 ± 1.09
SecondaryThwarted Belongingness

Thwarted belongingness will be measured with the belonging-specific subscale of the Interpersonal Needs Questionnaire (INQ). This self-report scale has a minimum of 9 and a maximum of 63 with higher scores representing a stronger feeling of loneliness and isolation. Scores of 36 or higher predict a higher risk for developing suicidal ideation.

Time frame:
Pre-treatment
Reported as:
Least squares mean · score on a scale
Thwarted Belongingness
score on a scaleScreened VeteranSecond Partner
Thwarted Belongingness31.26 ± 2.4328.32 ± 2.47
SecondaryThwarted Belongingness

Thwarted belongingness will be measured with the belonging-specific subscale of the Interpersonal Needs Questionnaire (INQ). This self-report scale has a minimum of 9 and a maximum of 63 with higher scores representing a stronger feeling of loneliness and isolation. Scores of 36 or higher predict a higher risk for developing suicidal ideation.

Time frame:
After Completing the BRC Program (1-3months after pre-treatment)
Reported as:
Least squares mean · score on a scale
Thwarted Belongingness
score on a scaleScreened VeteranSecond Partner
Thwarted Belongingness23.75 ± 2.5523.50 ± 2.55
SecondarySuicide Ideation Severity

Suicide ideation over the study will be monitored using the "Last Month" version of the Columbia Suicide Severity Rating Scale (CSSRS). This semi-structured interview has interviewers rate suicide ideation on a scale of 0 to 5, with scores of 3-5 placing individuals at high risk for attempt. VA hospitals use the C-SSRS across all clinics.

Time frame:
Pre-treatment
Reported as:
Count of participants · Participants
Suicide Ideation Severity
ParticipantsScreened VeteranSecond Partner
No ideation (Score=0)1820
Passive Death Ideation (Score=1)10
Ideation with Plan (Score=3)10
SecondarySuicide Ideation Severity

Suicide ideation over the study will be monitored using the "Last Month" version of the Columbia Suicide Severity Rating Scale (CSSRS). This semi-structured interview has interviewers rate suicide ideation on a scale of 0 to 5, with scores of 3-5 placing individuals at high risk for attempt. VA hospitals use the C-SSRS across all clinics.

Time frame:
After Completing the BRC Program (1-3months after pre-treatment)
Reported as:
Count of participants · Participants
Suicide Ideation Severity
ParticipantsScreened VeteranSecond Partner
No Ideation (Score=0)1417
Passive Death Ideation (Score=1)20
Suicidal Ideation with Plan (Score=3)00
SecondaryTreatment Acceptability

Treatment acceptability was assessed using the Client Satisfaction Questionnaire (CSQ, Larsen et al., 1979). Scores range from 1-4 with scores greater than 3 representing satisfaction with the treatment.

Time frame:
After Completing the BRC Program (1-3months after pre-treatment)
Reported as:
Mean · score on a scale
Treatment Acceptability
score on a scaleScreened VeteranSecond Partner
Treatment Acceptability3.49 ± 0.503.43 ± 0.52
Other pre-specifiedNumber of Mental Health and Family Contacts

Treatment engagement in mental health services will be assessed through a review of the electronic medical record. Staff will review appointments (e.g., individual, group, assessments) with a specific focus on general mental health services and couple/family support services (including Caregiver Support program and Intimate Partner Violence Assistance Program).

Time frame:
90 day period before pre-treatment session
Reported as:
Mean · days of care
Number of Mental Health and Family Contacts
days of careScreened VeteranSecond Partner
Number of Mental Health and Family Contacts3.39 ± 3.110.33 ± 0.58
Other pre-specifiedNumber of Mental Health and Family Contacts

Treatment engagement in mental health services will be assessed through a review of the electronic medical record. Staff will review appointments (e.g., individual, group, assessments) with a specific focus on general mental health services and couple/family support services (including Caregiver Support program and Intimate Partner Violence Assistance Program).

Time frame:
90 day period after final treatment session (earliest window 1-4mo after pre-treatment session and latest window 3-6mo)
Reported as:
Mean · days of care
Number of Mental Health and Family Contacts
days of careScreened VeteranSecond Partner
Number of Mental Health and Family Contacts4.78 ± 4.332.67 ± 3.79

Adverse events

Collected over Study duration from first to last assessment (1-3 months).. Non-serious events are listed at a 0% frequency threshold.

Adverse event summary by group
GroupDeathsSeriousOther
Screened Veteran0/20 (0%)0/20 (0%)1/20 (5%)
Second Partner0/20 (0%)0/20 (0%)1/20 (5%)
Most frequent other events
Most frequent other events
EventScreened VeteranSecond Partner
Intimate Partner Violence EventSocial circumstances1/201/20
Non-Suicidal Self-InjuryPsychiatric disorders0/200/20
Suicidal BehaviorPsychiatric disorders0/200/20

Baseline characteristics

This is a study of couples. Although all couples went through the same treatment, we provide separate demographics for Screened Veterans and Supporting Partners.

Age, Continuous
Age, Continuous(years)Screened VeteranSupporting PartnerTotal
Mean42.60 ± 13.6841.45 ± 13.9542.03 ± 13.65
Sex: Female, Male
Sex: Female, Male(Participants)Screened VeteranSupporting PartnerTotal
Female31720
Male17320
Ethnicity (NIH/OMB)
Ethnicity (NIH/OMB)(Participants)Screened VeteranSupporting PartnerTotal
Hispanic or Latino404
Not Hispanic or Latino162036
Unknown or Not Reported000
Race (NIH/OMB)
Race (NIH/OMB)(Participants)Screened VeteranSupporting PartnerTotal
American Indian or Alaska Native000
Asian011
Native Hawaiian or Other Pacific Islander000
Black or African American358
White141428
More than one race000
Unknown or Not Reported303
Region of Enrollment
Region of Enrollment(participants)Screened VeteranSupporting PartnerTotal
United States202040
Veteran Status
Veteran Status(Participants)Screened VeteranSupporting PartnerTotal
Veteran20222
Non-Veteran01818
07

Study locations

1 site
  • Finger Lakes Healthcare System (Canandaigua)
    Canandaigua, New York 14424, United States
08

References and documents

Study documents

  • Protocol and statistical analysis plan · Sep 1, 2021
  • Informed consent form · Mar 27, 2020

Documents are hosted by the registry — open the source record to download them.

Individual participant data

Plan to share: Yes — We will create deidentified datasets containing only variables used in a publication. This will be limited to the quantitative variables underlying publication to minimize likelihood of reidentification. Deidentified datasets will be stored in repositories if required for publication. Otherwise, they will be available on request to individual researchers with appropriate credentials.

Supporting information: Study protocol, Icf, Analytic code

09

Registry details

Key details

Study ID
NCT06011161
Lead sponsor
Canandaigua VA Medical Center
Collaborators
US Department of Veterans Affairs
Responsible party
Dev J. Crasta (Principal Investigator, Canandaigua VA Medical Center) — Principal investigator
First posted
Aug 25, 2023
Start date
Jan 28, 2020
Primary completion
Jul 20, 2021
Completion
Jul 20, 2021
Results posted
Oct 1, 2024
Last update
Oct 1, 2024

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
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