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CompletedNCT05988892Updated Mar 23, 2026

A Study of Physical Activity in Cancer Survivors

An interventional study of Physical Activity in Cancer, Hematopoietic and Lymphatic System Neoplasm and Malignant Solid Neoplasm, sponsored by Mayo Clinic. Completed at 4 sites in United States. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-03-23.

Sponsored by Mayo Clinic · Not applicable, Interventional, and Health services research

Phase
Not applicable
Study type
Interventional
Enrollment
100
Allocation
Not applicable
Ages
18 Years and older
Sex
All
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Study summary

The purpose of this study is to determine if increasing physical activity (PA) will increase physical functioning, as measured by cardiovascular endurance, muscular strength, and balance in underserved adult cancer survivors > 60 years of age and/or those of any age residing at a rural address. Also, to determine if increasing PA will increase quality of life (QOL), as measured by physical functioning and fatigue, in underserved cancer survivors >60 years of age and/or those of any age residing at a rural address.

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Conditions studied

  • Cancer
  • Hematopoietic and Lymphatic System Neoplasm
  • Malignant Solid Neoplasm

Keywords

  • Rural
  • Physical Activity
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In context

Neoplasms

9,365 studies on the registry are indexed under Neoplasms; 2,489 are open to participants now.

This study's enrollment of 100 is above the median of 50 across 7,253 interventional studies indexed under Neoplasms.

Browse Neoplasms studies →

Lead sponsor

Mayo Clinic is the lead sponsor of 3,218 studies on the registry; 670 are open to participants now.

Of its 445 completed or terminated interventional studies of FDA-regulated products, 313 (70%) have results posted.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • Adult, cancer survivors (no active disease) at Mayo Clinic Health System (MCHS) in Northwest Wisconsin (NWWI), Southwest Wisconsin (SWWI), Southeast Minnesota (SEMN), or Southwest Minnesota (SWMN)
  • Any stage cancer
  • Age >= 18 years residing at a rural address (as defined by Rural America, census.gov Urban Areas 2020 metric)
  • Age ≥ 18 years residing at a rural address (as defined by Rural America, census.gov)
  • Completed active treatment of surgery, (neo)adjuvant chemotherapy, and/or (neo) adjuvant radiation. Patients receiving adjuvant endocrine therapy, targeted therapy, or immunotherapy therapies are eligible.
  • Ownership of a computer/tablet/smartphone with internet access.
  • Willingness to create a google account and maintain the account for use of the Fitbit
  • Willingness and ability to attend study visits.
  • Must be able to complete semi-tandem (10 seconds), side-by-side tandem [10 seconds and short physical performance batters(SPPB)] Score of 6 or greater to qualify for virtual exercise.
  • Must be ambulatory without the use of assisted device(s).

Exclusion criteria

Exclusion Criteria:

  • Receiving surgery, (neo)adjuvant chemotherapy, (neo) adjuvant radiation, palliative treatment
  • Are already performing >150 minutes/week of moderate activity or 75 min/week of vigorous physical activity
  • Cancer-free for greater than 5 years
  • Unable to complete weekly interventions/exercise due to traveling or unable to be active for more than 7 consecutive days.
  • Squamous cell or basal cell skin cancers (melanoma still eligible)
  • Stage 0/in situ vulvar/cervical cancers
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Study design

Phase
Not applicable
Primary purpose
Health services research
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
100 participants (actual)

Study arms

  • Experimental
    Community Oncology patients entering cancer survivorship

    Patients participate in a virtual cancer rehabilitation program with weekly virtual visits by a cancer exercise specialist who provides a personalized synchronous exercise plan and receive bi-weekly phone calls/emails over 12 weeks. Patents also wear a Fitbit on study.

    Behavioral: Physical Activity

Interventions

  • BehavioralPhysical Activity

    Use Exercise to increase physical activity (PA), as measured by cardiovascular endurance, muscular strength, and balance in underserved cancer survivors \>60 years of age and/or those of any age residing at a rural address and to increase quality of life (QOL), as measured by physical functioning and fatigue, in underserved cancer survivors \>60 years of age and/or those of any age residing at a rural address.

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What researchers measure

Primary outcomes

  1. Change in physical functioning using Short Physical Performance Battery

    Change in physical functioning based on improvement in endurance, strength, and balance assessed using Short Physical Performance Battery (SPPB) pre- and post-12-week exercise intervention.

    Time frame: Baseline; 12 weeks

  2. Change in Quality of Life (QOL) using Patient-Reported Outcomes Measurement Information System (PROMIS)

    QOL evaluated based on physical functioning and fatigue, assessed using Patient-Reported Outcomes Measurement Information System (PROMIS) pre- and post-12-week exercise intervention.

    Time frame: Baseline; 12 weeks

  3. Change in satisfaction using a 5-point Likert scale

    Satisfaction assessed using a 5-point Likert scale following 12-week exercise intervention and participant-reporting likelihood of recommending program.

    Time frame: Baseline; 12 weeks

  4. Rate of adherence to program based on participation in virtual exercise sessions

    Adherence evaluated based on participation in virtual exercise sessions during 12-week exercise intervention.

    Time frame: Baseline; 12 weeks

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Study locations

4 sites
  • Mayo Clinic Health System in Albert Lea
    Albert Lea, Minnesota 56007, United States
  • Mayo Clinic Health System-Mankato
    Mankato, Minnesota 56001, United States
  • Mayo Clinic Health System-Eau Claire Clinic
    Eau Claire, Wisconsin 54701, United States
  • Mayo Clinic Health System-Franciscan Healthcare
    La Crosse, Wisconsin 54601, United States
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References and documents

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 23, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT05988892
Lead sponsor
Mayo Clinic
Responsible party
Sponsor
First posted
Aug 14, 2023
Start date
Jun 29, 2023
Primary completion
Apr 23, 2025
Completion
Apr 23, 2025
Last update
Mar 23, 2026

Study contacts

Kaye T. Sturz, APRN, CNP
principal investigator · Mayo Clinic Health System in Eau Claire

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Oct 2025. You cannot join it, but the record below documents what was studied.

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