An observational study in Diabetes Mellitus, sponsored by University of Bern. Recruiting at 1 site in Switzerland. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-12-08.
Sponsored by University of Bern · Observational
Exhaled volatile organic compounds will be measured during daytime with the goal to identifying circadian variability. The study incudes three subgroups: people without diabetes, people with type 1 diabetes, and people with type 2 diabetes. A total of 60 people will be recruited for the study.
10,925 studies on the registry are indexed under Diabetes Mellitus; 1,318 are open to participants now.
This study's planned enrollment of 60 is below the median of 233 across 2,218 observational studies indexed under Diabetes Mellitus.
Browse Diabetes Mellitus studies →University of Bern is the lead sponsor of 207 studies on the registry; 47 are open to participants now.
Counted across the registry records on this site, refreshed daily.
60 participants with the following subgroups: Subgroup 1: People without diabetes Subgroup 2: People diagnosed with T1D Subgroup 3: People diagnosed with T2D
Subgroup 1:
Subgroup 2:
Subgroup 3
Exclusion criteria
Other: Standardized meal
Other: Standardized meal
Other: Standardized meal
The participants will receive a standardized meal for breakfast
VOC Patterns over time as gallery plots
Gallery plots (3D visualization of retention index, drift time, ion current) from selected VOC peaks over time.
Time frame: During the study procedure (approximately 8 hours)
VOC Patterns over time as boxplots
Box plots from selected VOC peaks over time.
Time frame: During the study procedure (approximately 8 hours)
Capillary blood glucose
Correlation between capillary blood glucose and VOCs
Time frame: During the study procedure (approximately 8 hours)
Correlation between VOCs in breath intestinal microbiota
Correlation between VOCs in breath and intestinal microbiota species abundance
Time frame: day 1
Correlation between VOCs in breath oral microbiota
Correlation between VOCs in breath and oral microbiota species abundance
Time frame: day 1
Correlation between VOCs and subgroups
Wilcoxon signed-rank test will be used to explore if the patterns in VOCs differ between subgroup: people without diabetes, people living with T1D, and people living with T2D
Time frame: day 1 or 8 hours
Plan to share: No
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University of Bern