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RecruitingNCT05978934Updated Aug 7, 2023

Determining How Indoor Lighting Affects the Brain Health of Older Adults

An interventional study of Static Lighting Condition (L1) and Dynamic Lighting Condition (L2) in Sleep, Physical Activity and Cognitive Function, sponsored by Well Living Lab, Inc.. Recruiting at 1 site in United States. Open to participants aged 60 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2023-08-07.

Sponsored by Well Living Lab, Inc. · Not applicable, Interventional, and Prevention

From the registry’s dates

  • Primary completion was expected by Dec 2023, 2 years 10 months ago, but the record still lists the study as recruiting.
  • Started May 2023; still recruiting 3 years 4 months later.
Phase
Not applicable
Study type
Interventional
Enrollment
70
Allocation
Randomized
Ages
60 Years and older
Sex
All
01

Study summary

The goal of this randomized, cross-over, single-site trial followed by an exploratory third intervention is to understand how indoor lighting affects different measures of brain health in older adults living in independent living residences. This is a community based study occurring in a local senior living facility. The main question this study aims to answer is:

  • How does the quality of ambient indoor lighting an older adult is exposed to affect measures of brain health, such as sleep quality, physical activity, cognitive function, and social engagement?

Participants will be exposed to three different indoor lighting conditions for 4 weeks each while performing the following tasks:

  • Wear a smartwatch throughout the study to measure sleep quality and physical activity
  • Wear a small, wearable light sensor to measure light exposure during waking hours
  • Perform cognitive assessments throughout the study to detect any changes between each of the lighting conditions
  • Complete self-report of surveys to assess independence, social engagement, sleep quality, and mood

Results from these tasks will be compared within and between subjects to assess whether the different lighting conditions affect these different measures of brain health.

02

Conditions studied

  • Sleep
  • Physical Activity
  • Cognitive Function
  • Social Isolation
03

In context

Lead sponsor

Well Living Lab, Inc. is the lead sponsor of 2 studies on the registry; 1 is open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
60 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  1. At least age 60;
  2. Able to wear wearable devices throughout the study;
  3. Willing to have their lighting in their kitchen and dining areas changed and controlled for the study;
  4. Willing to have environmental sensors placed in their residence;
  5. Willing to provide contact information about their primary care provider (PCP); and
  6. Able and has capacity to provide informed consent (score > 14.5 based on UBACC consent capacity form).

Exclusion criteria

Exclusion Criteria:

  1. Is legally blind
  2. Previously renovated their living units and no longer have the standard lighting installation offered by the Senior Living Facility;
  3. Currently spend or plan to spend most of their day outside of their residence during the study (i.e., would not experience the indoor lighting intervention for the majority of the study);
  4. Plan to travel to a different time zone during the study; or
  5. Plan to be away from their residence for more than a week during the study.
05

Study design

Phase
Not applicable
Primary purpose
Prevention
Allocation
Randomized
Intervention model
Crossover assignment
Masking
None (open label)
Enrollment
70 participants (estimated)

Study arms

  • Active comparator
    L1 then L2 followed by L3 lighting condition

    Participants will first experience a static lighting condition (L1) then a dynamic lighting condition (L2). After, participants will experience another dynamic lighting condition (L3) with increased morning brightness compared to L2.

    Behavioral: Static Lighting Condition (L1) · Behavioral: Dynamic Lighting Condition (L2) · Behavioral: Dynamic Lighting Condition (L3)

  • Active comparator
    L2 then L1 followed by L3 lighting condition

    Participants will first experience a dynamic lighting condition (L2) then a static lighting condition (L1). After, participants will experience another dynamic lighting condition (L3) with increased morning brightness compared to L2.

    Behavioral: Static Lighting Condition (L1) · Behavioral: Dynamic Lighting Condition (L2) · Behavioral: Dynamic Lighting Condition (L3)

Interventions

  • BehavioralStatic Lighting Condition (L1)

    This indoor lighting condition keeps a constant brightness and correlated color temperature.

  • BehavioralDynamic Lighting Condition (L2)

    This indoor lighting condition has increased brightness and more blue correlated color temperature in the morning hours followed by decreased brightness and less blue correlated color temperature in the afternoon and evening hours.

  • BehavioralDynamic Lighting Condition (L3)

    This exploratory indoor lighting condition matches the same pattern as L2 except the brightness in the morning hours is increased.

06

What researchers measure

Primary outcomes

  1. Total Sleep Time

    Total sleep time per night in minutes as measured daily by a wearable device.

    Time frame: Change in total sleep time per night over the course of each condition of the 16-week study.

  2. Wake After Sleep Onset

    Wake after sleep onset per night in minutes as measured daily by a wearable device.

    Time frame: Change in wake after sleep onset per night over the course of each condition of the 16-week study.

  3. Sleep State Duration

    Sleep state duration per night in minutes as measured daily by a wearable device.

    Time frame: Change in sleep state duration per night over the course of each condition of the 16-week study.

Secondary outcomes

  1. Sleep Quality

    Self-report measurement of perceived sleep quality made daily via the Groningen Sleep Quality Survey.

    Time frame: Change in self-reported sleep quality over the course of each condition of the 16-week study.

  2. Steps Taken

    Physical activity in steps per day as measured daily by a wearable device.

    Time frame: Change in physical activity in steps per day over the course of each condition of the 16-week study.

  3. Physical Activity

    Physical activity in minutes per day as measured daily by a wearable device.

    Time frame: Change in physical activity in minutes per day over the course of each condition of the 16-week study.

  4. Working Memory

    Task performance on a working memory assessment taken twice weekly.

    Time frame: Change in working memory performance over the course of each condition of the 16-week study.

  5. Task Switching

    Task performance on a task switching assessment taken twice weekly.

    Time frame: Change in task switching performance over the course of each condition of the 16-week study.

  6. Response Inhibition

    Task performance on a response inhibition assessment taken twice weekly.

    Time frame: Change in response inhibition performance over the course of each condition of the 16-week study.

  7. Sustained-Attention Reaction Time

    Task performance on a sustained-attention reaction time assessment taken twice weekly.

    Time frame: Change in sustain-attention reaction time performance over the course of each condition of the 16-week study.

  8. Self-Reported Loneliness

    Self-report measurement of loneliness assessed weekly via the UCLA Loneliness Scale.

    Time frame: Change in self-reported loneliness over the course of each condition of the 16-week study.

  9. Self-Reported Depression

    Self-report measurement of depression assessed weekly via the Positive and Negative Affect Scale.

    Time frame: Change in self-reported depression over the course of each condition of the 16-week study.

  10. Self-Reported Mood

    Self-report measurement of mood assessed weekly via the Depression, Anxiety, and Stress Scale.

    Time frame: Change in self-reported mood over the course of each condition of the 16-week study.

07

Study locations

1 of 1 sites recruiting
  • The Waters on Mayowood
    Rochester, Minnesota 55901, United States
    • Tianna Bagley · Contact · wonm@thewaters.com · 507-252-2910
    • Christina Chen, MD · Principal investigator
    • Kevin A Mazurek, PhD · Principal investigator
    • Robert Klein, PhD · Principal investigator
    Recruiting
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 7, 2023, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT05978934
Lead sponsor
Well Living Lab, Inc.
Collaborators
Mayo Clinic
Responsible party
Sponsor
First posted
Aug 7, 2023
Start date
May 15, 2023
Primary completion
Dec 2023 (estimated)
Completion
Dec 2023 (estimated)
Last update
Aug 7, 2023

Study contacts

Robert Klein, PhD
Contact
robert.klein@delos.com
507-258-7592
Eric Heins
Contact
eric.heins@delos.com
507-259-0611

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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