An interventional study of e-Bandages in Healthy, sponsored by Mayo Clinic. Active, not recruiting at 1 site in United States. Open to participants aged 18 Years to 99 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-01-26.
Sponsored by Mayo Clinic · Not applicable, Interventional, and Other
A novel hydrogen peroxide-generating electrochemical bandage for wound infection treatment and prevention, and wound healing has been developed. The purpose of this research is to gather information on the safety and to confirm lack of toxicity of small hydrogen peroxide-generating e-bandages on normal human skin.
Mayo Clinic is the lead sponsor of 3,218 studies on the registry; 670 are open to participants now.
Of its 445 completed or terminated interventional studies of FDA-regulated products, 313 (70%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Four subjects will wear the e-Bandage on their skin for 24 hours, with active polarization for 3 hours.
Device: e-Bandages
Four subjects will wear the e-Bandage on their skin for 24 hours, with active polarization for 6 hours.
Device: e-Bandages
Four subjects will wear the e-Bandage on their skin for 24 hours, with active polarization for 12 hours.
Device: e-Bandages
Four subjects will wear the e-Bandage on their skin for 24 hours, with active polarization for 24 hours.
Device: e-Bandages
Four subjects will wear the e-Bandage on their skin for 24 hours, with no active polarization.
Device: e-Bandages
A hydrogen-peroxide generating e-bandage for wound infection and treatment and prevention. Each e-bandage is composed of three electrodes - a working, a counter, and a reference electrode. Cotton fabric physically separates electrodes. Constant (regulated) generation of low-concentrations of hydrogen peroxide happens on the working electrode, which is in contact with the skin covered with a hydrogel layer.
e-Bandage Discomfort
Self-report discomfort with the e-Bandage, graded on a scale of 1-4, with 1 being no reaction, 2 mild reaction, 3 moderate reaction, 4 severe reaction.
Time frame: Approximately 3 - 24 hours
Skin irritation/dermatitis
Skin redness or swelling, graded on a scale of 1-4, with 1 being no reaction, 2 mild reaction, 3 moderate reaction, 4 severe reaction.
Time frame: Approximately 3 - 24 hours
Allergic Reaction
Local/systemic allergic reaction to the e-Bandage, graded on a scale of 1-4, with 1 being no reaction, 2 mild reaction, 3 moderate reaction, 4 severe reaction.
Time frame: Approximately 3 - 24 hours
Skin Discoloration
Skin discoloration from the e-Bandage, graded on a scale of 1-4, with 1 being no reaction, 2 mild reaction, 3 moderate reaction, 4 severe reaction.
Time frame: Approximately 3 - 24 hours
Plan to share: No
This study is active, not recruiting, as verified in Jan 2026. You cannot join it, but the record below documents what was studied.
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