An observational study in Healthy, sponsored by Precordior Ltd. Completed at 1 site in Finland. Open to participants aged 18 Years to 65 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-07-14.
Sponsored by Precordior Ltd · Observational
The goal of this study is to produce a solution to measure the cardiorespiratory fitness (CRF), which can be used by commercially available smartphones without extra equipment, add-ons and special know-how.
This observational study with follow-up is to test the feasibility of a new non-invasive cardiac measurement method (gyrocardiography, GCG) in detecting hemodynamic parameters to measure exercise capacity and cardiorespiratory fitness in healthy subjects.
The objective is to produce a solution which can be used to measure the exercise capacity and cardiorespiratory fitness (CRF) of the exercisers, keep-fit athletes and professional athletes using hemodynamic parameters such as:
Participants are either athletes or non-athletic persons. The athletes will perform spiroergometry and non-athletic persons ergometry to measure the CRF expressed as VO2max.
Following parameters will be measured during the (spiro)ergometry:
The GCG measurements for acquiring the hemodynamic parameters are performed before and after the (spiro)ergometry using smartphone. During a 1- minute GCG measurement, the smart phone is placed on the chest in the middle of the sternum.
Precordior Ltd is the lead sponsor of 4 studies on the registry; 1 is open to participants now.
Counted across the registry records on this site, refreshed daily.
Healthy subjects from the area of Turku. Half of the subjects (n=100) are allocated to athletic group (moderate to high Physical activity, PA, levels according to International Physical Activity Questionnaire, IPAQ) and other half (n=100) to non-athletic group (low levels of PA according to IPAQ).
Follow-up visit:
Exclusion Criteria:
Moderate to high PA levels according to IPAQ.
Diagnostic Test: Ergospirometry
Low levels of PA according to IPAQ.
Diagnostic Test: Ergometry
Maximal exercise test is performed on a cycle ergometer (Ergoline 800 s; VIASYS Healthcare, Germany). The test begins at a workload of 50 W, which is increased by 25 W (males) every 1 min or the test begins with 25 W which is increased by 25 W (females) every 1 min until exhaustion. The mean workload during the last 4 min of work is calculated and the VO2max is estimated according to the American College of Sports Medicine (American College of Sports Medicine. ACSM's guidelines for exercise testing and prescription. Sixth edition. Baltimore: Williams \& Wilkins 2000:304). Blood lactate concentration is measured immediately and 1 min after exhaustion from capillary samples (Biosen C-Line Glucose and Lactate analyzer, EKFdiagnostic GmbH, Germany). (Pahkala et al. 2013.)
VO2max is measured using a stationary bicycle ergometer (Ergoline 800 s; VIASYS Healthcare, Germany. For males, the test starts with 100 W which is increased by 25 W every 1 min until volitional exhaustion. For females, the test starts with 50 W which is increased by 25 W every 1 min until volitional exhaustion. Ventilation and gas exchange (Vyntus CPX, Vyaire Medical Gmbh, Leibnizstrasse, Hoechberg, Germany) are measured during the test. Subject's blood lactate concentration is measured from capillary samples immediately and 1 min after exhaustion (Biosen C-Line Glucose and Lactate analyzer, EKF-diagnostic GmbH, Germany). The heart rate of the participants is followed continuously (CardioSoft GE, CardioSoft V6.51; GE Medical Systems Information Technologies, USA). (Heiskanen et al. 2021.)
The maximum (max) rate (V) of oxygen (O₂) your body is able to use during exercise.
Time frame: 4 minutes
Gyrocardiography measurement
Lasts 1 minute and is performed at least once at rest before the (spiro)ergometry.
Time frame: 1 minute
Gyrocardiography measurement
Lasts 1 minute and is performed 3 minutes after the (spiro)ergometry.
Time frame: 3 minutes
Heart rate per minute and Heart rate variability
Lasts 1 minute and is performed at least once at rest before the (spiro)ergometry.
Time frame: 1 minute
Heart rate per minute and Heart rate variability
Lasts 1 minute and is performed 3 minutes after the (spiro)ergometry.
Time frame: 3 minutes
Systolic and diastolic phase (blood pressure RR)
Will be performed at least once at rest before the (spiro)ergometry.
Time frame: 1 minute
Respiration rate per minute
Lasts 1 minute and is performed at least once at rest before the (spiro)ergometry.
Time frame: 1 minute
Respiration rate per minute
Lasts 1 minute and is performed 3 minutes after the (spiro)ergometry.
Time frame: 3 minutes
Cardiac Strength profile
Lasts 1 minute and is performed at least once at rest before the (spiro)ergometry.
Time frame: 1 minute
Cardiac Strength profile
Lasts 1 minute and is performed 3 minutes after the (spiro)ergometry.
Time frame: 3 minutes
This study is completed, as verified in Jul 2025. You cannot join it, but the record below documents what was studied.
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