A Phase 4 interventional study of Propofol 10 MG/ML Injection and Sevoflurane Inhalation Liquid in General Anesthetic Drug Adverse Reaction, sponsored by Damanhour Teaching Hospital. Completed at 1 site in Egypt. Open to participants aged 21 Years and older. Per ClinicalTrials.gov, last updated 2025-02-05.
Sponsored by Damanhour Teaching Hospital · Phase 4, Interventional, and Other
Background: The choice of appropriate anesthetics is essential to protect brain function, decrease perioperative complications, and provide high-quality care, and better quality of life.
Objectives: To compare the efficacy and safety of propofol versus sevoflurane in patients undergoing elective, non-cardiac operations under general anesthesia.
Methods: This was a randomized (1:1), parallel, phase four clinical trial; carried out on 44 patients, who were candidates for elective, non-cardiac operations under general anesthesia at our hospital. Patients were randomly allocated into two equal groups in which anesthesia was maintained with propofol infusion in group P and sevoflurane inhalation in group S.
437 studies on the registry are indexed under Drug-Related Side Effects and Adverse Reactions; 76 are open to participants now.
This study's enrollment of 44 is below the median of 103 across 255 interventional studies indexed under Drug-Related Side Effects and Adverse Reactions.
Browse Drug-Related Side Effects and Adverse Reactions studies →Damanhour Teaching Hospital is the lead sponsor of 14 studies on the registry; 5 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Propofol group
Drug: Propofol 10 MG/ML Injection
Sevoflurane group
Drug: Sevoflurane Inhalation Liquid
Propofol infusion
Sevoflurane inhalation
Mean and Standard deviation of Neuron Specific Enolase enzyme (µg/L) in blood serum (mean±SD)
Before operation (T0), 1 hour after the end of operation (T1), 24 hours the end of operation (T2)
Time frame: 24 hours after the end of operation
This study is completed, as verified in Jan 2024. You cannot join it, but the record below documents what was studied.
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Drug-Related Side Effects and Adverse Reactions→
Damanhour Teaching Hospital