Acupuncture Therapy Combined With Breathing Training for Patients With Stroke Complicated

Browse trials for

• Lung Diseases 3,306
• Stroke 7,263

Keywords

• Acupuncture therapy
• Respiratory training
• Seroinflammatory factors
• Lung function

Study arms

• Experimental
  the intervention group

  TCM acupuncture therapy Conventional drug therapy Rehabilitation therapy Breathing training

  Device: TCM acupuncture therapy · Drug: Conventional drug therapy · Behavioral: Rehabilitation therapy · Behavioral: Breathing training

• Active comparator
  the control group

  Conventional drug therapy Rehabilitation therapy Breathing training

  Drug: Conventional drug therapy · Behavioral: Rehabilitation therapy · Behavioral: Breathing training

Interventions

• DeviceTCM acupuncture therapy

  TCM acupuncture therapy: Zusanli, Quchi, Hegu, Taichong, Feishu and Fenglong were selected as the main acupoints, and the auxiliary acupoints were selected according to the symptoms, including Fengchi, Dazhui, Lieque, Tiantu, Shenshu, Zhongfu, etc.

• DrugConventional drug therapy

  Antibiotics were selected based on drug sensitivity test results. Patients with body temperature \> 38.5℃ were treated with physical cooling and antipyretic drugs. In patients whose sputum was thick and difficult to cough up, nebulization and inhalation therapy was given, as well as effective coughing and patting the back to expel phlegm were guided.

• BehavioralRehabilitation therapy

  Comprehensive training for hemiplegic limbs included a joint range of motion training, bridging exercise, turnover training, balance training, gait training, hand function training and self-care ability training, 40 min/d, 6 times/w.

• BehavioralBreathing training

  Training was conducted daily in the morning, or after symptom relief in the case of fever or other discomforts, once a day, 30-40 min/time.

Primary outcomes

1. Serum inflammatory factors：C-reactive protein (CRP) level

   C-reactive protein (CRP) level(mg/L)

   Time frame: 2 Weeks

2. Serum inflammatory factors：Calcitonin (PCT) level

   Calcitonin (PCT) level(ng/mL)

   Time frame: 2 Weeks

3. Serum inflammatory factors：WBC

   WBC (x 109/L)

   Time frame: 2 Weeks

4. Improvement time for symptoms and signs of pulmonary infection：Time of fever relieving

   the time for body temperature to return to normal (d)

   Time frame: 2 Weeks

5. Improvement time for symptoms and signs of pulmonary infection：Time for the disappearance of cough

   the time for the disappearance of cough (d)

   Time frame: 2 Weeks

6. Improvement time for symptoms and signs of pulmonary infection：Time for the disappearance of expectoration

   the time for the disappearance of expectoration (d)

   Time frame: 2 Weeks

7. Improvement time for symptoms and signs of pulmonary infection：Time for the disappearance of moist rales

   the time for the disappearance of moist rales (d)

   Time frame: 2 Weeks

8. TCM syndrome score

   Before and after treatment, TCM syndrome scores were counted in the two groups. The main and secondary symptoms were classified into 4 levels, with scores of 0, 1, 2 and 3 based on the severity of the symptoms. The tongue coating and pulse pattern were scored into 2 levels, with no scored as 0 and yes as 1. The sum of various scores was calculated as the total score, with a score range of 0-36. The higher the score, the severer the condition.

   Time frame: 2 Weeks

9. Clinical pulmonary infection score (CPIS)

   Before and after treatment, the 2 groups were scored comprehensively based on the average range of 12-h body temperature, WBC range, amount and character of tracheal secretions, index of gas exchange, pulmonary infiltration shadow of X-ray chest film, and pathogenic bacteria in sputum culture. According to the severity, they were divided into 3 levels, with a score of 0, 1 and 2. The maximum score was 12. The higher the score, the severer the infection.

   Time frame: 2 Weeks

10. Pulmonary indexes:forced vital capacity (FVC)

    To measure the forced vital capacity (FVC)(L) before and after treatment

    Time frame: 2 Weeks

11. Pulmonary indexes:forced expiratory volume in the first second (FEV1)

    To measure the forced expiratory volume in the first second (FEV1)(L/S) before and after treatment

    Time frame: 2 Weeks

12. Pulmonary indexes: peak expiratory flow (PEF)

    To measure the peak expiratory flow (PEF)(L/S) before and after treatment

    Time frame: 2 Weeks

13. Efficacy evaluation:Number of patients with clinical efficacy（Cured，Effective，Remarkably effective，Invalid）

    Efficacy was evaluated according to the Criteria of Diagnosis and Therapeutic Effect of Diseases and Symptoms in Traditional Chinese Medicine . Cured: Clinical adverse symptoms such as cough, expectoration and chest tightness disappeared, inflammation was absorbed on X-ray or CT, and routine blood indexes were normal. Remarkably effective: Adverse symptoms such as cough, expectoration and chest tightness were improved significantly, and X-ray or CT and routine blood test results basically returned to normal. Effective: Clinical adverse symptoms such as cough, expectoration and chest tightness were relieved, and X-ray or CT and routine blood test results were improved partially. Invalid: Clinical adverse symptoms such as cough, expectoration and chest tightness had no changes or aggravated.

    Time frame: 2 Weeks