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Status unknownNCT05903677Updated Jun 15, 2023

The Relationship Between Preoperative Levels of Ionized Magnesium and Risk of Acute Kidney Injury After Cardiac Surgery

An observational study in Magnesium Disorder, sponsored by Assiut University. Status unknown. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2023-06-15.

Sponsored by Assiut University · Observational

The sponsor has not verified this record recently (last verified Jun 2023), so the status shown — last known as Not yet recruiting — may be out of date.
Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
50
Ages
18 Years and older
Sex
All
01

Study summary

Detection the relationship between preoperative ionized magnesium levels and the risk of acute kidney injury after cardiac surgery.

Read the detailed description

Acute kidney injury (AKI) is a major medical problem that is of particular concern after cardiac surgery. The reported prevalence of cardiac surgery-associated acute kidney injury (CSA-AKI) is up to 30% and is independently associated with an increase of morbidity and mortality .So this study is for measuring preoperative ionized magnesium levels of patients who will undergo cardiac surgeries then measuring postoperative serum creatinine, BUN and urine output to detect if they developed AKI or not and if there is a relationship between the post cardiac surgery AKI and preoperative ionized magnesium levels.

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Conditions studied

  • Magnesium Disorder
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In context

Lead sponsor

Assiut University is the lead sponsor of 5,050 studies on the registry; 2,174 are open to participants now.

Of its 14 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Sampling method
Non-probability sample

Study population

people more than or equal 18 years who undergo open heart surgery between July 2023 to July 2024 and not known to have kidney disease .

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  1. patients more than or equal 18 yrs.
  2. patients undergoing cardiac surgery between July 2023 and July 2024

Exclusion criteria

Exclusion Criteria:

  1. patients with known Kidney disease.
  2. patients less than 18 yrs
05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
50 participants (estimated)
Patient registry
No

Groups and cohorts

  • Adults undergoing cardiac surgery without preoperative renal affection

    Detect the preoperative magnesium levels in adults undergoing cardiac surgery without preoperative renal affection and follow up if they developed postoperative acute kidney injury or not.

    Other: magnesium levels

Interventions

  • Othermagnesium levels

    Detection of the relationship between cardiac surgery associated AKI and preoperative magnesium levels.

    Also known as: Serum creatinine and blood urea nitrogen (BUN)

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What researchers measure

Primary outcomes

  1. Post cardiac surgery AKI according to KDIGO criteria with low preoperative magnesium level

    Measuring preoperative magnesium level and postoperative kidney functions in form of serum creatinine in umol/L , BUN in mmol/L and urine output ml/h to detect the relationship between preoperative low magnesium level and risk of acute kidney injury after cardiac surgery.

    Time frame: Baseline

  2. Post cardiac surgery AKI according to KDIGO criteria with normal or high preoperative magnesium level

    Measuring preoperative magnesium level and postoperative serum creatinine, BUN and urine output to detect the relationship between preoperative magnesium level and risk of acute kidney injury after cardiac surgery.

    Time frame: basline

  3. Post cardiac surgery normal kidney functions with low preoperative magnesium level

    Measuring preoperative magnesium level and postoperative serum creatinine, BUN and urine output to detect the relationship between preoperative magnesium level and risk of acute kidney injury after cardiac surgery.

    Time frame: basline

07

Study locations

No study locations are listed for this record.

08

References and documents

Publications

  • Koh HB, Jung CY, Kim HW, Kwon JY, Kim NH, Kim HJ, Jhee JH, Han SH, Yoo TH, Kang SW, Park JT. Preoperative Ionized Magnesium Levels and Risk of Acute Kidney Injury After Cardiac Surgery. Am J Kidney Dis. 2022 Nov;80(5):629-637.e1. doi: 10.1053/j.ajkd.2022.03.004. Epub 2022 Apr 23. PubMed 35469966 ↗
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jun 15, 2023, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT05903677
Lead sponsor
Assiut University
Responsible party
Mostafa Ahmed Kaleed Abdelhalim (Resident doctor, Assiut University) — Principal investigator
First posted
Jun 15, 2023
Start date
Jul 2023 (estimated)
Primary completion
Jun 2024 (estimated)
Completion
Jul 2024 (estimated)
Last update
Jun 15, 2023

Study contacts

Mostafa Ahmed
Contact
mostafakaleed21@gmail.com
01113038074
Samir Kamal
Contact
samirkotb45@yahoo.com
01062949199

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Jun 2023. You cannot join it, but the record below documents what was studied.

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