ClinicalTrials.gg
Status unknownNCT05846828Updated Jul 19, 2023

Cognitive Functions in Breastfed Preschool Children

An observational study in Breast Feeding, sponsored by Assiut University. Status unknown. Open to participants aged 3 Years to 5 Years. Per ClinicalTrials.gov, last updated 2023-07-19.

Sponsored by Assiut University · Observational

The sponsor has not verified this record recently (last verified Jul 2023), so the status shown — last known as Not yet recruiting — may be out of date.
Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
150
Ages
3 Years to 5 Years
Sex
All
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Study summary

The current work aims to assess of the cognitive development in breastefed children and compare it with artificially fed children as well as the duration of breastfeeding.

Read the detailed description

Breastfeeding provides nutritional and immunological benefits to infants and also prevents infections . Breastfeeding also has clear short-term benefits for child survival through reduction of morbidity and mortality from infectious diseases. Breastfeeding also has longterm benefits .Breastfeeding improves cognitive development and emotional interactions between the mother and infant .A previous meta-analysis of 20 studies that compared breastfeeding with formula-feeding reported that breastfeeding is associated with significantly improved cognitive development from infancy to adolescence .The results of a meta-analysis of these studies showed that breastfeeding was associated with an increase of 3•5 points (95% CI 1•9-5•0) on intelligence tests at childhood and adolescence. This beneficial effect of breastfeeding could be due to the presence of long-chain polyunsaturated fatty acids, such as arachidonic acid and docosahexaenoic acid in breast milk . Breastfed infants have higher concentrations of these fatty acids that are positively associated with brain development .

Child cognitive development is influenced by genetic and environmental factors . The child has a genetically determined potential for cognitive development. However environmental factors, such as adequate nutrition and the parents' ability to create a good and stimulating home environment may also have a positive influence on the child's cognitive development .Several studies have shown a positive correlation between breast feeding and cognitive development in children . In this study we measure the mental development of children by the use of Stanford binet intelligence test. It is a cognitive and intelligence test that is used diagnose developmental and intellectual deficiencies in young children .

Other risk factors affecting children's mental development should be taken in consideration like the mothers' age, educational level (lower than high school, high school diploma, college degree, university degree, and higher than a university degree), family income, job status (employed/unemployed), sex of infant, gestational age, and infant birth weight.

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Conditions studied

  • Breast Feeding

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Keywords

  • cognitive functions
  • IQ
  • Stanford binet test
03

In context

Breast Feeding

289 studies on the registry are indexed under Breast Feeding; 119 are open to participants now.

This study's planned enrollment of 150 is below the median of 167 across 55 observational studies indexed under Breast Feeding.

Browse Breast Feeding studies →

Lead sponsor

Assiut University is the lead sponsor of 5,050 studies on the registry; 2,174 are open to participants now.

Of its 14 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
3 Years to 5 Years
Sexes eligible
All
Sampling method
Non-probability sample

Study population

preschool children aged from 3 to 5 years

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Children more than 3 years and till age of 5 years that present to Assiut University Hospital with acute diseases.

Exclusion criteria

Exclusion Criteria:

  1. Children known to have chronic disease.
  2. Chidren with History of birth anoxia, birth trauma, kernictrus, epilepsy, metabolic diseases.
  3. Positive family history of mental retardation.
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Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
150 participants (estimated)
Patient registry
No

Interventions

  • OtherStanford Binet IQ test

    The Fourth Edition Stanford-Binet test which is based upon a four-factor model of intelligence, and its 15 subtests are partitioned into : 1. Verbal ability. 2. Abstract/Visual ability. 3. Quantaitive potential. 4. Short-Term Memory Scales

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What researchers measure

Primary outcomes

  1. assess the cognitive development in breastefed children by the use of Stanford binet intelligence test and compare it with artificially fed children as well as the duration of breastfeeding.

    In this study we measure the mental development of breast fed and artificailly fed preschool children by the use of Stanford binet intelligence test to prove that breastfed children have higher IQ than artificially fed chidren

    Time frame: Baseline

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Study locations

No study locations are listed for this record.

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References and documents

Publications

  • Golding J, Rogers IS, Emmett PM. Association between breast feeding, child development and behaviour. Early Hum Dev. 1997 Oct 29;49 Suppl:S175-84. doi: 10.1016/s0378-3782(97)00062-5. PubMed 9363425 ↗
  • Fergusson DM, Beautrais AL, Silva PA. Breast-feeding and cognitive development in the first seven years of life. Soc Sci Med. 1982;16(19):1705-8. doi: 10.1016/0277-9536(82)90096-x. PubMed 7178917 ↗
  • Lee H, Park H, Ha E, Hong YC, Ha M, Park H, Kim BN, Lee B, Lee SJ, Lee KY, Kim JH, Jeong KS, Kim Y. Effect of Breastfeeding Duration on Cognitive Development in Infants: 3-Year Follow-up Study. J Korean Med Sci. 2016 Apr;31(4):579-84. doi: 10.3346/jkms.2016.31.4.579. Epub 2016 Feb 22. PubMed 27051242 ↗
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 19, 2023, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT05846828
Lead sponsor
Assiut University
Responsible party
Romany Eissa Atya Eissa (Principal Investigator, Assiut University) — Principal investigator
First posted
May 6, 2023
Start date
Sep 1, 2023 (estimated)
Primary completion
Apr 1, 2024 (estimated)
Completion
Feb 1, 2025 (estimated)
Last update
Jul 19, 2023

Study contacts

Romany Eissa Atya
Contact
romany.eissa@yahoo.com
01221695657
Emad EL-Deen Mahmoud Hammad, prof
principal investigator · Assiut University
Amr Mohamed Kotb, lecturer
principal investigator · Assiut University

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Jul 2023. You cannot join it, but the record below documents what was studied.

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