An observational study in Sarcopenic Obesity and Body Composition, sponsored by Fujian Medical University. Completed at 1 site in China. Open to participants aged 16 Years to 65 Years. Per ClinicalTrials.gov, last updated 2023-04-24.
Sponsored by Fujian Medical University · Observational
The purpose of this study is to assess the impact of sarcopenic obesity (SO) on weight loss outcomes and improvement of quality of life after laparoscopic sleeve gastrectomy.
Sarcopenic obesity is a state in which a lack of muscle mass and strength coexists with an increase in fat mass, and it may affect the health outcome of people with obesity after laparoscopic sleeve gastrectomy (LSG).No studies have reported differences in weight loss outcomes between patients with SO and those with non-sarcopenic obesity (NSO) after LSG. Therefore, this study aimed to systematically evaluate the differences in weight loss and quality of life (QOL) evaluation between patients with SO and NSO after LSG and provide high-level evidence-based medical evidence for the impact of SO on weight loss in the obese population and refinement of follow-up strategies.
6,296 studies on the registry are indexed under Obesity; 1,692 are open to participants now.
This study's enrollment of 245 is above the median of 135 across 1,283 observational studies indexed under Obesity.
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This retrospective monocentric study included 260 obese patients who underwent LSG between January 2015 and July 2022 at the Department of Gastric Surgery, Fujian Medical University Union Hospital. All patients underwent a thorough multidisciplinary evaluation (an endocrinologist, dietician, and bariatric surgeon), and a psychiatric evaluation was obtained if considered necessary. All patients completed routine preoperative investigations, including upper gastrointestinal endoscopy, chest radiography, abdominal computed tomography (CT), abdominal ultrasound examination, and nutritional assessment. Preoperative QOL was measured using the Moorhead-Ardelt questionnaire at the same visit.
All patients in this study were operated on by the same surgical team of surgeons with more than 60 LSG experiences.Postoperative treatment was performed based on the patient's condition.
Exclusion Criteria:
Patients who underwent LSG with FM/FFM\>0.80 calculated from the cross-sectional CT image of L3 vertebra.
Procedure: Laparoscopic sleeve gastrectomy
Patients who underwent LSG with FM/FFM\<0.80 calculated from the cross-sectional CT image of L3 vertebra.
Procedure: Laparoscopic sleeve gastrectomy
Laparoscopic sleeve gastrectomy was performed in all patients with or without SO.
%EWL
Percentage excess weight loss is calculated as (initial weight - 6-month weight)/(initial weight - ideal weight) × 100%.
Time frame: 6 month after surgery
%EWL
Percentage excess weight loss is calculated as (initial weight - 1-month weight)/(initial weight - ideal weight) × 100%.
Time frame: 1 month after surgery
%EWL
Percentage excess weight loss is calculated as (initial weight - 3-month weight)/(initial weight - ideal weight) × 100%.
Time frame: 3 month after surgery
%EWL
Percentage excess weight loss is calculated as (initial weight - 9-month weight)/(initial weight - ideal weight) × 100%.
Time frame: 9 month after surgery
%EWL
Percentage excess weight loss is calculated as (initial weight - 12-month weight)/(initial weight - ideal weight) × 100%.
Time frame: 12 month after surgery
%TWL
Percentage total weight loss is calculated as (initial weight - 6-month weight)/(initial weight) × 100%
Time frame: 6 month after surgery
%TWL
Percentage total weight loss is calculated as (initial weight - 12-month weight)/(initial weight) × 100%
Time frame: 12 month after surgery
EBMI
Excess BMI is calculated as(follow-up BMI - ideal BMI)
Time frame: 6 month after surgery
%WL
Percentage weight loss is calculated as (follow-up weight/initial weight) × 100%
Time frame: 6 month after surgery
MA II score
Moorhead-Ardelt QOL questionnaire is a six-item self-report questionnaire that assesses the patient's subjective impression of QOL,The total score ranges from -3 to +3 and defines five outcome groups: very poor, poor, fair, good, and very good. Good and very good outcomes were considered satisfactory.
Time frame: 6 month after surgery
BAROS score
The Bariatric Analysis and Reporting Outcome System(BAROS)combines the Moorhead-Ardelt QOL questionnaire with other data relevant to bariatric surgery, including the %EWL, improvement in comorbid conditions, and complications.A BAROS score ≤1 was considered a failure; \>1-3, fair; \>3-5, good; \>5-7, very good; and \>7, excellent.
Time frame: 6 month after surgery
This study is completed, as verified in Apr 2023. You cannot join it, but the record below documents what was studied.
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Fujian Medical University