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Status unknownNCT05800314Updated Apr 5, 2023

Effectiveness of Different Scoring Systems

An observational study in Healthy, sponsored by Assiut University. Status unknown. Per ClinicalTrials.gov, last updated 2023-04-05.

Sponsored by Assiut University · Observational

The sponsor has not verified this record recently (last verified Mar 2023), so the status shown — last known as Not yet recruiting — may be out of date.
Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
90
Sex
All
01

Study summary

  1. Assessment of the effectiveness of a validated poisoning specific scoring system (new poisoning mortality [PMS]) and other commonly used scoring systems for all acutely ill patient (Simple clinical score [SCS] and Rapid Emergency Medicine Score [REMS]) at Assiut university hospitals.
  2. Comparison between these scoring systems in terms of sensitivity and specificity in both children and adults.
  3. Design a toxicological sheet for Assiut poison control center that include this poisoning scoring system so it could help in assessing prognosis of acute poisoned cas
Read the detailed description

Acute poisoning is a global health problem. Prevention of mortality in both intentional and accidental poisonings is essential(Cheung et al., 2018) Regarding prevalence in Egypt, 38470 pediatric patients presentedd to Ain Shams University -Poisoning Toxicology Center(ASU-PTC) 2009-2013 (Sonya et al., 2016) .Also, 937 adult poisoned patients were admitted to Tanta Emergency University hospital in 2012 (Enas, 2012).

Mortality prediction in acute poisoning cases has been explored by applying various clinical scoring systems used in critical care (Alizadeh et al, 2014; Banderas-Bravo et al., 2017) .

There are different non-specific scoring systems that depend physiological variables only such as:

  1. The acute physiology and chronic health evaluation (APACHE) score
  2. Simplified Acute physiology score (SAPS) They are commonly applied tools in the intensive care unit; they are used for predicting the outcomes in poisoning cases. But they became of limited utility because they are time consuming. (Bilgin et al., 2005).

There are other non-specific scoring system but non time consuming such as

  1. Rapid Emergency Medicine Score (REMS) was a powerful predictor of in hospital mortality in patients attending the ED
  2. Simple Clinical Score (SCS) a quickly and accurately identifying patients at both a low and high risk of death. (J Kellett,et al ,2006) New Poisoning Mortality Score (PMS):is specific scoring system that depends on demographic variables, poisoning related variables and vital signs, so accurately predicted the probability of death for patients with acute poisoning. This could contribute to the clinical decision making for patients with acute poisoning at the ED (Han et al., 2021). Results indicated that 724 poisoning cases were admitted to Children's Hospital during the year 2012 in Assuit governorate, Prediction of prognosis in patients with acute poisoning has a clinical significance i.e., it helps in timely and appropriate treatment. However, toxicology research lacks a well-accepted method for assessing the severity of poisoning (Cheung et al., 2018). There is a lack in using and including this scoring systems in daily assessing of patients. Thus, the objective of this study is to assess the efficacy of a poisoning specific scoring system (PMS) and other nonspecific, physiologic, and rapid scoring systems (REMS and SCS). This could assist in treatment and therapeutic decision making at early stages for patients with acute poisoning.
02

Conditions studied

  • Healthy
03

In context

Lead sponsor

Assiut University is the lead sponsor of 4,901 studies on the registry; 2,098 are open to participants now.

Of its 13 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Sampling method
Non-probability sample

Study population

Prospective cross- sectional study.

Inclusion criteria

  • 1-All symptomatic cases with acute toxicity admitted to emergency units of Assiut university hospital and Assiut University Children hospital. Diagnosis based on history taking, clinical examination of the patients, toxicological investigations if available, and exclusion of relevant differential diagnoses.

2- Willing and able to comply with the study procedures and provide a written informed consent to participate in the study

Exclusion criteria

Exclusion Criteria:

  • Patients with a history of renal, hepatic, CNS, and cardiac diseases and cance
  • Patients who will be transferred from the initial ED to another hospital. Patients who have incomplete data on poisoning-related variables
  • Pregnant women.- Patient presented with a delay more than 48
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Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
90 participants (estimated)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. need for intubation, need for ICU and hospital

    The patients need for intubation, ICU,hospital stay

    Time frame: Baseline

Secondary outcomes

  1. Mortality was assessed during the hospital stay of the patients till discharge.

    Measure the mortality for acute poisoning

    Time frame: Baseline

07

Study locations

No study locations are listed for this record.

08

References and documents

Individual participant data

Plan to share: Undecided

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Apr 5, 2023, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT05800314
Lead sponsor
Assiut University
Responsible party
Raghda Mostafa Shaban Ali (Effectiveness of Different Scoring Systems in Prediction of Prognosis in Acute Intoxicated Cases in Assiut University Hospitals, Assiut University) — Principal investigator
First posted
Apr 5, 2023
Start date
Nov 2023 (estimated)
Primary completion
Nov 2024 (estimated)
Completion
Dec 2024 (estimated)
Last update
Apr 5, 2023

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Mar 2023. You cannot join it, but the record below documents what was studied.

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